Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+T cells

Egr2 and 3 Inhibit T-bet–Mediated IFN-γ Production in T Cells

(2017) Randeep Singh et al.   JOURNAL OF IMMUNOLOGY

FOXO1 opposition of CD8+T cell effector programming confers early memory properties and phenotypic diversity

(2017) Arnaud Delpoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-150-Mediated Foxo1 Regulation Programs CD8 + T Cell Differentiation

(2017) Young Ho Ban et al.   Cell Reports

T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections

(2016) Daniel T. Utzschneider et al.   IMMUNITY

cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection

(2016) Chan-Wang J. Lio et al.   JOURNAL OF VIROLOGY

Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

(2016) Katherine C. Verbist et al.   NATURE

FOXO1 couples metabolic activity and growth state in the vascular endothelium

(2016) Kerstin Wilhelm et al.   NATURE

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation

(2016) Kristen N Pollizzi et al.   NATURE IMMUNOLOGY

A decade of transcription factor-mediated reprogramming to pluripotency

(2016) Kazutoshi Takahashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Immune-surveillance through exhausted effector T-cells

(2016) Dietmar Zehn et al.   Current Opinion in Virology

CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive Therapies

(2016) Corinne J. Smith et al.   Frontiers in Immunology

Long live FOXO: unraveling the role of FOXO proteins in aging and longevity

(2015) Rute Martins et al.   AGING CELL

Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes

(2015) Muttiah Barathan et al.   APOPTOSIS

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2

(2015) Yu Mi Oh et al.   Nature Communications

FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC

(2015) Peng Tan et al.   Scientific Reports

The viral context instructs the redundancy of costimulatory pathways in driving CD8+ T cell expansion

(2015) Suzanne PM Welten et al.   eLife

Generating diversity: transcriptional regulation of effector and memory CD8+T-cell differentiation

(2015) Rachel L. Rutishauser et al.   IMMUNOLOGICAL REVIEWS

The Transcription Factor FoxO1 Sustains Expression of the Inhibitory Receptor PD-1 and Survival of Antiviral CD8+ T Cells during Chronic Infection

(2014) Matthew M. Staron et al.   IMMUNITY

Detection of self-reactive CD8+T cells with an anergic phenotype in healthy individuals

(2014) Yuka Maeda et al.   SCIENCE

The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection

(2013) Myoungjoo V. Kim et al.   IMMUNITY

Differentiation of CD8 memory T cells depends on Foxo1

(2013) Rodrigo Hess Michelini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Age-Associated Increase of Low-Avidity Cytomegalovirus-Specific CD8+ T Cells That Re-Express CD45RA

(2013) S. J. Griffiths et al.   JOURNAL OF IMMUNOLOGY

Natural Killer Cell Dependent Within-Host Competition Arises during Multiple MCMV Infection: Consequences for Viral Transmission and Evolution

(2013) Andrea R. McWhorter et al.   PLoS Pathogens

Antagonism between FOXO and MYC Regulates Cellular Powerhouse

(2013) Barrie Peck et al.   Frontiers in Oncology

Foxp3-independent loss of regulatory CD4+T-cell suppressive capacities induced by self-deprivation

(2012) Arnaud Delpoux et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Transcription Factor Foxo1 Represses T-bet-Mediated Effector Functions and Promotes Memory CD8+ T Cell Differentiation

(2012) Rajesh R. Rao et al.   IMMUNITY

Viral latency drives ‘memory inflation’: a unifying hypothesis linking two hallmarks of cytomegalovirus infection

(2012) Christof K. Seckert et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

T cell exhaustion in protozoan disease

(2012) Jason P. Gigley et al.   TRENDS IN PARASITOLOGY

Bcl-2 Allows Effector and Memory CD8+ T Cells To Tolerate Higher Expression of Bim

(2011) S. Kurtulus et al.   JOURNAL OF IMMUNOLOGY

FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

(2011) Xin Zhang et al.   NATURE CELL BIOLOGY

The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets

(2011) Cliff Y Yang et al.   NATURE IMMUNOLOGY

Applications of post-translational modifications of FoxO family proteins in biological functions

(2011) Ying Zhao et al.   Journal of Molecular Cell Biology

Memory CD8+ T cell differentiation

(2010) Joshua J. Obar et al.   Annals of the New York Academy of Sciences

GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness

(2010) Chan C. Whiting et al.   FEBS Journal

Foxo Transcription Factors Control Regulatory T Cell Development and Function

(2010) Yann M. Kerdiles et al.   IMMUNITY

Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1

(2010) Xinyuan Zhou et al.   IMMUNITY

Generation of effector CD8+ T cells and their conversion to memory T cells

(2010) Weiguo Cui et al.   IMMUNOLOGICAL REVIEWS

Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

(2010) G. Jeannet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive Activation of Wnt Signaling Favors Generation of Memory CD8 T Cells

(2009) D.-M. Zhao et al.   JOURNAL OF IMMUNOLOGY

The FoxO code

(2008) D R Calnan et al.   ONCOGENE