The viral context instructs the redundancy of costimulatory pathways in driving CD8+ T cell expansion

Plasticity in programming of effector and memory CD8+T-cell formation

(2015) Ramon Arens et al.   IMMUNOLOGICAL REVIEWS

T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses

(2014) Sigrid S. Skånland et al.   BIOCHEMICAL JOURNAL

Type I Interferon Protects Antiviral CD8+ T Cells from NK Cell Cytotoxicity

(2014) Haifeng C. Xu et al.   IMMUNITY

Type I Interferons Protect T Cells against NK Cell Attack Mediated by the Activating Receptor NCR1

(2014) Josh Crouse et al.   IMMUNITY

Control of Memory CD8+ T Cell Differentiation by CD80/CD86-CD28 Costimulation and Restoration by IL-2 during the Recall Response

(2014) S. Fuse et al.   JOURNAL OF IMMUNOLOGY

Endogenous 4-1BB Ligand Plays a Critical Role in Protection from Influenza-Induced Disease

(2014) G. H. Y. Lin et al.   JOURNAL OF IMMUNOLOGY

Deciphering the role of DC subsets in MCMV infection to better understand immune protection against viral infections

(2014) Yannick O. Alexandre et al.   Frontiers in Microbiology

Environmental Cues Dictate the Fate of Individual CD8+ T Cells Responding to Infection

(2013) Courtney R. Plumlee et al.   IMMUNITY

The contextual role of TNFR family members in CD8+T-cell control of viral infections

(2013) Michael E. Wortzman et al.   IMMUNOLOGICAL REVIEWS

The Context of Gene Expression Defines the Immunodominance Hierarchy of Cytomegalovirus Antigens

(2013) I. Dekhtiarenko et al.   JOURNAL OF IMMUNOLOGY

Priming of CD8+ T Cells against Cytomegalovirus-Encoded Antigens Is Dominated by Cross-Presentation

(2013) A. Busche et al.   JOURNAL OF IMMUNOLOGY

CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus Infection

(2013) S. P. M. Welten et al.   JOURNAL OF VIROLOGY

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

The distinct role of T cell costimulation in antiviral immunity

(2013) Suzanne PM Welten et al.   Current Opinion in Virology

Pathogen-Specific Inflammatory Milieux Tune the Antigen Sensitivity of CD8+ T Cells by Enhancing T Cell Receptor Signaling

(2012) Martin J. Richer et al.   IMMUNITY

The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity

(2012) Jonathan M. Coquet et al.   IMMUNITY

CD70 Deficiency Impairs Effector CD8 T Cell Generation and Viral Clearance but Is Dispensable for the Recall Response to Lymphocytic Choriomeningitis Virus

(2012) I. Munitic et al.   JOURNAL OF IMMUNOLOGY

Signal 3 Cytokines as Modulators of Primary Immune Responses during Infections: The Interplay of Type I IFN and IL-12 in CD8 T Cell Responses

(2012) Selina Jessica Keppler et al.   PLoS One

Memory T cell inflation: understanding cause and effect

(2012) Geraldine A. O’Hara et al.   TRENDS IN IMMUNOLOGY

Batf3 transcription factor-dependent DC subsets in murine CMV infection: Differential impact on T-cell priming and memory inflation

(2011) Nicole Torti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Type-I IFN drives the differentiation of short-lived effector CD8+T cells in vivo

(2011) Melanie Wiesel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Signal 3 requirement for memory CD8+T-cell activation is determined by the infectious pathogen

(2011) Selina J. Keppler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathogen-Induced Inflammatory Environment Controls Effector and Memory CD8 + T Cell Differentiation

(2011) Joshua J. Obar et al.   JOURNAL OF IMMUNOLOGY

Differential B7–CD28 Costimulatory Requirements for Stable and Inflationary Mouse Cytomegalovirus-Specific Memory CD8 T Cell Populations

(2011) Ramon Arens et al.   JOURNAL OF IMMUNOLOGY

Opposing Effects of CD70 Costimulation during Acute and Chronic Lymphocytic Choriomeningitis Virus Infection of Mice

(2011) P. Penaloza-MacMaster et al.   JOURNAL OF VIROLOGY

Multiple Layers of CD80/86-Dependent Costimulatory Activity Regulate Primary, Memory, and Secondary Lymphocytic Choriomeningitis Virus-Specific T Cell Immunity

(2011) J. Eberlein et al.   JOURNAL OF VIROLOGY

Direct activation of antigen-presenting cells is required for CD8+ T-cell priming and tumor vaccination

(2011) W. Kratky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of IFN-α as a signal-3 cytokine on human naïve and antigen-experienced CD8+ T cells

(2010) Sandra Hervas-Stubbs et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8+ T cells

(2010) Ian R. Humphreys et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice

(2010) Shahram Salek-Ardakani et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of CD80/CD86 in Generation and Maintenance of Functional Virus-Specific CD8+ T Cells in Mice Infected with Lymphocytic Choriomeningitis Virus

(2010) M. Grujic et al.   JOURNAL OF IMMUNOLOGY

B7-Mediated Costimulation of CD4 T Cells Constrains Cytomegalovirus Persistence

(2010) R. Arens et al.   JOURNAL OF VIROLOGY

An Enigmatic Tail of CD28 Signaling

(2010) J. S. Boomer et al.   Cold Spring Harbor Perspectives in Biology

Lymphotoxin-Mediated Crosstalk between B Cells and Splenic Stroma Promotes the Initial Type I Interferon Response to Cytomegalovirus

(2008) Kirsten Schneider et al.   Cell Host & Microbe

Constitutive Activation of the PrfA Regulon Enhances the Potency of Vaccines Based on Live-Attenuated and Killed but Metabolically Active Listeria monocytogenes Strains

(2008) P. Lauer et al.   INFECTION AND IMMUNITY