AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy

The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

(2016) Jeff Sevigny et al.   NATURE

Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease

(2016) Matthew R. Brier et al.   Science Translational Medicine

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

(2016) Seung-Hye Lee et al.   Cell Reports

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model

(2015) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

(2015) Hirohide Asai et al.   NATURE NEUROSCIENCE

Invited review: Prion-like transmission and spreading of tau pathology

(2015) Florence Clavaguera et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models

(2015) Sethu Sankaranarayanan et al.   PLoS One

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

(2014) Zeshan Ahmed et al.   ACTA NEUROPATHOLOGICA

Neuronal activity regulates extracellular tau in vivo

(2014) Kaoru Yamada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteopathic tau seeding predicts tauopathy in vivo

(2014) B. B. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Chain Fragment Variable Passive Immunotherapies for Neurodegenerative Diseases

(2013) Liang Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo

(2013) Kiran Yanamandra et al.   NEURON

Capsid Serotype and Timing of Injection Determines AAV Transduction in the Neonatal Mice Brain

(2013) Paramita Chakrabarty et al.   PLoS One

Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity

(2013) Cristina d’Abramo et al.   PLoS One

scFv Antibody: Principles and Clinical Application

(2012) Zuhaida Asra Ahmad et al.   Clinical & Developmental Immunology

Chronic Administration of an Aglycosylated Murine Antibody of Ponezumab Does Not Worsen Microhemorrhages in Aged Tg2576 Mice

(2012) Gary B. Freeman et al.   Current Alzheimer Research

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Microtubule-Stabilizing Agent, Epothilone D, Reduces Axonal Dysfunction, Neurotoxicity, Cognitive Deficits, and Alzheimer-Like Pathology in an Interventional Study with Aged Tau Transgenic Mice

(2012) B. Zhang et al.   JOURNAL OF NEUROSCIENCE

An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A  Binding Properties Promotes Neuroprotection and Glial Engulfment of A 

(2012) O. Adolfsson et al.   JOURNAL OF NEUROSCIENCE

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

(2012) Cristian A. Lasagna-Reeves et al.   Scientific Reports

Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models

(2011) Xiyun Chai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

(2011) Allal Boutajangout et al.   JOURNAL OF NEUROCHEMISTRY

The Natively Unfolded Character of Tau and Its Aggregation to Alzheimer-like Paired Helical Filaments†

(2008) Sadasivam Jeganathan et al.   BIOCHEMISTRY