Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors
Authors
Keywords
-
Journal
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Volume 32, Issue 1, Pages 1042-1052
Publisher
Informa UK Limited
Online
2017-08-04
DOI
10.1080/14756366.2017.1354857
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action
- (2016) Maria Luisa Villalba et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds
- (2016) Bünyamin Özgeriş et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII
- (2016) Elisabetta Barresi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds
- (2016) Adel S. El-Azab et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and anticholinesterase activity of coumarin-3-carboxamides bearing tryptamine moiety
- (2016) Samaneh Ghanei-Nasab et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies
- (2016) Benedetta Cornelio et al. JOURNAL OF MEDICINAL CHEMISTRY
- The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain
- (2016) Silvia Fossati et al. NEUROBIOLOGY OF DISEASE
- New natural product carbonic anhydrase inhibitors incorporating phenol moieties
- (2015) Anastasia Karioti et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Carbonic anhydrase inhibitors: Design, synthesis, kinetic, docking and molecular dynamics analysis of novel glycine and phenylalanine sulfonamide derivatives
- (2015) İsmail Fidan et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII
- (2015) Alessio Nocentini et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones
- (2015) Akın Akıncıoğlu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives
- (2015) Semra Işık et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, biological evaluation, and docking studies of novel thiourea derivatives of bisindolylmethane as carbonic anhydrase II inhibitor
- (2015) Syahrul Imran et al. BIOORGANIC CHEMISTRY
- Kinetic andin silicostudies of hydroxy-based inhibitors of carbonic anhydrase isoforms I and II
- (2015) Ramin Ekhteiari Salmas et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- In silicoinvestigation of PARP-1 catalytic domains inholoandapostates for the design of high-affinity PARP-1 inhibitors
- (2015) Ramin Ekhteiari Salmas et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Synthesis of Some Novel Norbornene-Fused Pyridazines as Potent Inhibitors of Carbonic Anhydrase and Acetylcholinesterase
- (2015) Ramazan Kocak et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins
- (2015) Marta Ferraroni et al. JOURNAL OF MEDICINAL CHEMISTRY
- 6-Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells
- (2015) Aiga Grandane et al. JOURNAL OF MEDICINAL CHEMISTRY
- Dendrimers incorporating benzenesulfonamide moieties strongly inhibit carbonic anhydrase isoforms I–XIV
- (2015) Fabrizio Carta et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use
- (2015) Jaromir Pastorek et al. SEMINARS IN CANCER BIOLOGY
- Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series
- (2015) Joanna Ombouma et al. ACS Medicinal Chemistry Letters
- A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors
- (2014) Nikolaus Krall et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- New aminobenzenesulfonamide–thiourea conjugates: Synthesis and carbonic anhydrase inhibition and docking studies
- (2014) Sumera Zaib et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design and synthesis of coumarin-3-acylamino derivatives to scavenge radicals and to protect DNA
- (2014) Yang Yang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups
- (2014) Murat Bozdag et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Class of 4-Sulfamoylphenyl-ω-aminoalkyl Ethers with Effective Carbonic Anhydrase Inhibitory Action and Antiglaucoma Effects
- (2014) Murat Bozdag et al. JOURNAL OF MEDICINAL CHEMISTRY
- Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model
- (2014) Tineke W. H. Meijer et al. PLoS One
- 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors
- (2013) Muhammet Tanc et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Inhibition of mammalian carbonic anhydrases I-XIV with grayanotoxin III: solution and in silico studies
- (2013) Serdar Durdagi et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX
- (2013) Aditi Sharma et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition
- (2012) Isao Nishimori et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases
- (2012) Kaspars Tars et al. JOURNAL OF MEDICINAL CHEMISTRY
- Carbonic anhydrase inhibitors and activators for novel therapeutic applications
- (2011) Claudiu T Supuran Future Medicinal Chemistry
- Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors
- (2011) Nadia Touisni et al. JOURNAL OF MEDICINAL CHEMISTRY
- Ureido-Substituted Benzenesulfonamides Potently Inhibit Carbonic Anhydrase IX and Show Antimetastatic Activity in a Model of Breast Cancer Metastasis
- (2011) Fabio Pacchiano et al. JOURNAL OF MEDICINAL CHEMISTRY
- Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations
- (2010) Jason Wagner et al. BIOORGANIC & MEDICINAL CHEMISTRY
- 7,8-Disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range
- (2010) Alfonso Maresca et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Drug Design Studies of the Novel Antitumor Targets Carbonic Anhydrase IX and XII
- (2010) O. Guler et al. CURRENT MEDICINAL CHEMISTRY
- Modulation of Carbonic Anhydrase 9 (CA9) in Human Brain Cancer
- (2010) Harun M. Said et al. CURRENT PHARMACEUTICAL DESIGN
- Synthesis and biological evaluation of a 99mTc-labelled sulfonamide conjugate for in vivo visualization of carbonic anhydrase IX expression in tumor hypoxia
- (2010) Vamsidhar Akurathi et al. NUCLEAR MEDICINE AND BIOLOGY
- Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties†‡
- (2009) Caroli Genis et al. BIOCHEMISTRY
- Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target
- (2009) Giuseppina De Simone et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins
- (2009) Alfonso Maresca et al. JOURNAL OF MEDICINAL CHEMISTRY
- Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors#
- (2009) Alfonso Maresca et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent Developments of Carbonic Anhydrase Inhibitors as Potential Anticancer Drugs
- (2008) Anne Thiry et al. JOURNAL OF MEDICINAL CHEMISTRY
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now