Hypothalamic effects of neonatal diet: reversible and only partially leptin dependent

Early life disruption to the ghrelin system with over-eating is resolved in adulthood in male rats

(2017) Luba Sominsky et al.   NEUROPHARMACOLOGY

Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice

(2016) Eun Ran Kim et al.   BEHAVIOURAL BRAIN RESEARCH

AgRP Neuron-Specific Deletion of Glucocorticoid Receptor Leads to Increased Energy Expenditure and Decreased Body Weight in Female Mice on a High-Fat Diet

(2016) Miyuki Shibata et al.   ENDOCRINOLOGY

miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions

(2016) Susu Mao et al.   Journal of Neuroinflammation

Neonatal overfeeding induces early decline of the ovarian reserve: Implications for the role of leptin

(2016) Luba Sominsky et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward

(2016) Rahul Pandit et al.   NEUROPSYCHOPHARMACOLOGY

Blockage of neonatal leptin signaling induces changes in the hypothalamus associated with delayed pubertal onset and modifications in neuropeptide expression during adulthood in male rats

(2016) Virginia Mela et al.   PEPTIDES

Blockage of the Neonatal Leptin Surge Affects the Gene Expression of Growth Factors, Glial Proteins, and Neuropeptides Involved in the Control of Metabolism and Reproduction in Peripubertal Male and Female Rats

(2015) Virginia Mela et al.   ENDOCRINOLOGY

Neurons for hunger and thirst transmit a negative-valence teaching signal

(2015) J. Nicholas Betley et al.   NATURE

A neural basis for melanocortin-4 receptor–regulated appetite

(2015) Alastair S Garfield et al.   NATURE NEUROSCIENCE

Neonatal overfeeding attenuates acute central pro-inflammatory effects of short-term high fat diet

(2015) Guohui Cai et al.   Frontiers in Neuroscience

Neonatal overnutrition causes early alterations in the central response to peripheral ghrelin

(2015) Gustav Collden et al.   Molecular Metabolism

Aminoprocalcitonin-mediated suppression of feeding involves the hypothalamic melanocortin system

(2013) Eva Tavares et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ischemic brain injury: A consortium analysis of key factors involved in mesenchymal stem cell-mediated inflammatory reduction

(2013) Colin P. McGuckin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Distinct glutamatergic and GABAergic subsets of hypothalamic pro-opiomelanocortin neurons revealed by in situ hybridization in male rats and mice

(2013) Gábor Wittmann et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Early leptin blockade predisposes fat-fed rats to overweight and modifies hypothalamic microRNAs

(2013) Charlotte Benoit et al.   JOURNAL OF ENDOCRINOLOGY

Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively

(2013) C. Zhan et al.   JOURNAL OF NEUROSCIENCE

Oral Leptin Treatment in Suckling Rats Ameliorates Detrimental Effects in Hypothalamic Structure and Function Caused by Maternal Caloric Restriction during Gestation

(2013) Jadwiga Konieczna et al.   PLoS One

Leptin-sensitive neurons in the arcuate nuclei contribute to endogenous feeding rhythms

(2012) Ai-Jun Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cdh1 Is Essential for Endometrial Differentiation, Gland Development, and Adult Function in the Mouse Uterus1

(2012) Sarah N. Reardon et al.   BIOLOGY OF REPRODUCTION

Refeeding-Activated Glutamatergic Neurons in the Hypothalamic Paraventricular Nucleus (PVN) Mediate Effects of Melanocortin Signaling in the Nucleus Tractus Solitarius (NTS)

(2012) Praful S. Singru et al.   ENDOCRINOLOGY

Distinct Roles for Specific Leptin Receptor Signals in the Development of Hypothalamic Feeding Circuits

(2012) S. G. Bouret et al.   JOURNAL OF NEUROSCIENCE

Effects of Neonatal Overfeeding on Juvenile and Adult Feeding and Energy Expenditure in the Rat

(2012) Aneta Stefanidis et al.   PLoS One

The influence of orexins on the firing rate and pattern of rat intergeniculate leaflet neurons - electrophysiological and immunohistological studies

(2011) Dobromila Pekala et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Postnatal Overfeeding Leads to Obesity and Exacerbated Febrile Responses to Lipopolysaccharide Throughout Life

(2011) M. A. Clarke et al.   JOURNAL OF NEUROENDOCRINOLOGY

Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring

(2011) Ana Paula García et al.   PLoS One

PDK1-Foxo1 in Agouti-Related Peptide Neurons Regulates Energy Homeostasis by Modulating Food Intake and Energy Expenditure

(2011) Yongheng Cao et al.   PLoS One

Postnatal leptin is necessary for maturation of numerous organs in newborn rats

(2011) Linda Attig et al.   Organogenesis

Early Overnutrition Results in Early-Onset Arcuate Leptin Resistance and Increased Sensitivity to High-Fat Diet

(2010) Maria M. Glavas et al.   ENDOCRINOLOGY

Development and Characterization of High Affinity Leptins and Leptin Antagonists

(2010) Michal Shpilman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Central and Peripheral Administration of Secretin Inhibits Food Intake in Mice through the Activation of the Melanocortin System

(2010) Carrie Yuen Yee Cheng et al.   NEUROPSYCHOPHARMACOLOGY

Developmental changes in hypothalamic leptin receptor: relationship with the postnatal leptin surge and energy balance neuropeptides in the postnatal rat

(2009) E. C. Cottrell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Moderate caloric restriction during gestation results in lower arcuate nucleus NPY- and αMSH-neurons and impairs hypothalamic response to fed/fasting conditions in weaned rats

(2009) A. P. García et al.   DIABETES OBESITY & METABOLISM

Early Life Origins of Obesity: Role of Hypothalamic Programming

(2009) Sebastien G Bouret   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neonatal overfeeding alters adult anxiety and stress responsiveness

(2009) Sarah J. Spencer et al.   PSYCHONEUROENDOCRINOLOGY

Leptin-dependent STAT3 phosphorylation in postnatal mouse hypothalamus

(2008) Andrea Frontini et al.   BRAIN RESEARCH

Peripheral injection of ghrelin induces Fos expression in the dorsomedial hypothalamic nucleus in rats

(2008) Peter Kobelt et al.   BRAIN RESEARCH

Early postnatal leptin blockage leads to a long-term leptin resistance and susceptibility to diet-induced obesity in rats

(2008) L Attig et al.   INTERNATIONAL JOURNAL OF OBESITY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Administration of IL-1β to the 4th ventricle causes anorexia that is blocked by agouti-related peptide and that coincides with activation of tyrosine-hydroxylase neurons in the nucleus of the solitary tract

(2008) Mark D. DeBoer et al.   PEPTIDES

Mechanisms of Leptin Action and Leptin Resistance

(2007) Martin G. Myers et al.   Annual Review of Physiology

Maternal Perinatal Undernutrition Drastically Reduces Postnatal Leptin Surge and Affects the Development of Arcuate Nucleus Proopiomelanocortin Neurons in Neonatal Male Rat Pups

(2007) Fabien Delahaye et al.   ENDOCRINOLOGY