30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Nongenomic effects via the mineralocorticoid receptor

Caveolin-1/-3: therapeutic targets for myocardial ischemia/reperfusion injury

(2016) Yang Yang et al.   BASIC RESEARCH IN CARDIOLOGY

Aldosterone Production and Signaling Dysregulation in Obesity

(2016) Andrea Vecchiola et al.   CURRENT HYPERTENSION REPORTS

Acute effect of mineralocorticoid receptor antagonism on vascular function in healthy older adults

(2016) Moon-Hyon Hwang et al.   EXPERIMENTAL GERONTOLOGY

Aldosterone mediates metastatic spread of renal cancer via the G protein–coupled estrogen receptor (GPER)

(2016) Ross D. Feldman et al.   FASEB JOURNAL

Obligatory role for GPER in cardiovascular aging and disease

(2016) M. R. Meyer et al.   Science Signaling

Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases

(2016) Alessandro Cannavo et al.   Nature Communications

Caveolin 1 Modulates Aldosterone‐Mediated Pathways of Glucose and Lipid Homeostasis

(2016) Rene Baudrand et al.   Journal of the American Heart Association

Obligatory role for GPER in cardiovascular aging and disease

(2016) M. R. Meyer et al.   Science Signaling

Aldosterone stimulates the cardiac sodium/bicarbonate cotransporter via activation of the g protein-coupled receptor gpr30

(2015) Verónica C. De Giusti et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

What have we learned about GPER function in physiology and disease from knockout mice?

(2015) Eric R. Prossnitz et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Role of Nongenomic Signaling Pathways Activated by Aldosterone During Cardiac Reperfusion Injury

(2015) Anthony W. Ashton et al.   MOLECULAR ENDOCRINOLOGY

Emerging roles of GPER in diabetes and atherosclerosis

(2015) Matthias Barton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Diabetes impairs the vascular effects of aldosterone mediated by G protein-coupled estrogen receptor activation

(2015) Nathanne S. Ferreira et al.   Frontiers in Pharmacology

Aldosterone's Rapid, Nongenomic Effects Are Mediated by Striatin: A Modulator of Aldosterone's Effect on Estrogen Action

(2014) Patricia Coutinho et al.   ENDOCRINOLOGY

Akt-mediated cardioprotective effects of aldosterone in type 2 diabetic mice

(2014) Loubina Fazal et al.   FASEB JOURNAL

Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption

(2014) Tengis S. Pavlov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spironolactone for Heart Failure with Preserved Ejection Fraction

(2014) Bertram Pitt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis

(2013) Jeremy W. Roy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Dexamethasone induces caveolin-1 in vascular endothelial cells: implications for attenuated responses to VEGF

(2013) Junsuke Igarashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aldosterone mediates its rapid effects in vascular endothelial cells through GPER activation

(2013) Robert Gros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension

(2013) Ioana R. Preston et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms

(2013) Dong Chen et al.   GENE

STRIPAK complexes: Structure, biological function, and involvement in human diseases

(2013) Juyeon Hwang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cross-talk between mineralocorticoid receptor/angiotensin II type 1 receptor and mitogen-activated protein kinase pathways underlies aldosterone-induced atrial fibrotic responses in HL-1 cardiomyocytes

(2013) Chin-Feng Tsai et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Atorvastatin Suppresses Aldosterone-induced Neonatal Rat Cardiac Fibroblast Proliferation by Inhibiting ERK1/2 in the Genomic Pathway

(2013) Qian Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Aldosterone increases cardiac vagal tone via G protein-coupled oestrogen receptor activation

(2013) G. Cristina Brailoiu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aldosterone-induced ENaC and basal Na+/K+-ATPase trafficking via protein kinase D1-phosphatidylinositol 4-kinaseIIIβ trans Golgi signalling in M1 cortical collecting duct cells

(2013) Ruth Dooley et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Anatomical location and redistribution of G protein-coupled estrogen receptor-1 during the estrus cycle in mouse kidney and specific binding to estrogens but not aldosterone

(2013) Shi-Bin Cheng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Mineralocorticoid receptor interaction with SP1 generates a new response element for pathophysiologically relevant gene expression

(2013) Sandra Meinel et al.   NUCLEIC ACIDS RESEARCH

Angiotensin II-aldosterone interaction in human coronary microarteries involves GPR30, EGFR, and endothelial NO synthase

(2012) W. W. Batenburg et al.   CARDIOVASCULAR RESEARCH

Rapid Estrogen Receptor Signaling Is Essential for the Protective Effects of Estrogen Against Vascular Injury

(2012) Sophie J. Bernelot Moens et al.   CIRCULATION

Extrarenal effects of aldosterone

(2012) Aurelie Nguyen Dinh Cat et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Aldosterone Induces Kidney Fibroblast Proliferation via Activation of Growth Factor Receptors and PI3K/MAPK Signalling

(2012) L.L. Huang et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Activation of the Mineralocorticoid Receptor Increases Striatin Levels

(2011) L. H. Pojoga et al.   AMERICAN JOURNAL OF HYPERTENSION

Aldosterone-induced brain MAPK signaling and sympathetic excitation are angiotensin II type-1 receptor dependent

(2011) Zhi-Hua Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Aldosterone Induces Vascular Insulin Resistance by Increasing Insulin-Like Growth Factor-1 Receptor and Hybrid Receptor

(2011) Shamshad J. Sherajee et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: role of PDGFR

(2011) Glaucia E. Callera et al.   CARDIOVASCULAR RESEARCH

Aldosterone Stimulates the Cardiac Na + /H + Exchanger via Transactivation of the Epidermal Growth Factor Receptor

(2011) Verónica C. De Giusti et al.   HYPERTENSION

GPR30 Expression Is Required for the Mineralocorticoid Receptor–Independent Rapid Vascular Effects of Aldosterone

(2011) Robert Gros et al.   HYPERTENSION

Variants of the Caveolin-1 Gene: A Translational Investigation Linking Insulin Resistance and Hypertension

(2011) Luminita H. Pojoga et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor–dependent pathway

(2011) Shigeru Shibata et al.   JOURNAL OF CLINICAL INVESTIGATION

Dietary sodium intake regulates angiotensin II type 1, mineralocorticoid receptor, and associated signaling proteins in heart

(2011) Vincent Ricchiuti et al.   JOURNAL OF ENDOCRINOLOGY

Action of ANP on the nongenomic dose-dependent biphasic effect of aldosterone on NHE1 in proximal S3 segment

(2011) C. Braga-Sobrinho et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice

(2010) Luminita H. Pojoga et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Central interactions of aldosterone and angiotensin II in aldosterone- and angiotensin II-induced hypertension

(2010) Baojian Xue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Colocalization of mineralocorticoid and EGF receptor at the plasma membrane

(2010) Claudia Grossmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Aldosterone Enhances IGF-I-Mediated Signaling and Biological Function in Vascular Smooth Muscle Cells

(2010) Teresa Cascella et al.   ENDOCRINOLOGY

Caveolin-1 Ablation Reduces the Adverse Cardiovascular Effects ofN-ω-Nitro-l-Arginine Methyl Ester and Angiotensin II

(2010) Luminita H. Pojoga et al.   ENDOCRINOLOGY

Elevated Mineralocorticoid Receptor Activity in Aged Rat Vascular Smooth Muscle Cells Promotes a Proinflammatory Phenotype via Extracellular Signal-Regulated Kinase 1/2 Mitogen-Activated Protein Kinase and Epidermal Growth Factor Receptor-Dependent Pathways

(2010) Alexander W. Krug et al.   HYPERTENSION

C-Reactive Protein Makes Human Endothelium Stiff and Tight

(2010) Kristina Kusche-Vihrog et al.   HYPERTENSION

Aldosterone and Mineralocorticoid Receptor Antagonists Modulate Elastin and Collagen Deposition in Human Skin

(2010) Thomas F. Mitts et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Protein kinase D1 modulates aldosterone-induced ENaC activity in a renal cortical collecting duct cell line

(2010) Victoria McEneaney et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

AS160 Modulates Aldosterone-stimulated Epithelial Sodium Channel Forward Trafficking

(2010) Xiubin Liang et al.   MOLECULAR BIOLOGY OF THE CELL

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nitric oxide release follows endothelial nanomechanics and not vice versa

(2010) Johannes Fels et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel

(2010) Alexey V. Karpushev et al.   PLoS One

Aldosterone Promotes Fibronectin Synthesis in Rat Mesangial Cells via ERK1/2-Stimulated Na+-H+ Exchanger Isoform 1

(2009) Minmin Zhang et al.   AMERICAN JOURNAL OF NEPHROLOGY

Differential regulation of H+-ATPases in MDCK-C11 cells by aldosterone and vasopressin

(2009) Priscilla M.C. Dos Santos et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Glucocorticoids Activate Cardiac Mineralocorticoid Receptors During Experimental Myocardial Infarction

(2009) Anastasia S. Mihailidou et al.   HYPERTENSION

Aldosterone Increases Oxidant Stress to Impair Guanylyl Cyclase Activity by Cysteinyl Thiol Oxidation in Vascular Smooth Muscle Cells

(2009) Bradley A. Maron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aldosterone Stimulates Elastogenesis in Cardiac Fibroblasts via Mineralocorticoid Receptor-independent Action Involving the Consecutive Activation of Gα13, c-Src, the Insulin-like Growth Factor-I Receptor, and Phosphatidylinositol 3-Kinase/Akt

(2009) Severa Bunda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nitric Oxide-mediated Dilation of Arterioles to Intraluminal Administration of Aldosterone

(2009) Erwan Heylen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells

(2009) Rona Limor et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation

(2009) Victoria McEneaney et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

New aspects of rapid aldosterone signaling

(2009) C. Grossmann et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aldosterone regulation of intestinal Na absorption involves SGK-mediated changes in NHE3 and Na+ pump activity

(2008) Mark W. Musch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Aldosterone and Angiotensin II Synergistically Stimulate Migration in Vascular Smooth Muscle Cells Through c-Src-Regulated Redox-Sensitive RhoA Pathways

(2008) A.C. Montezano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vasoconstrictor effect of aldosterone via angiotensin II type 1 (AT1) receptor: possible role of AT1 receptor dimerization

(2008) M. Yamada et al.   CARDIOVASCULAR RESEARCH

Aldosterone Induces Cardiotrophin-1 Expression in HL-1 Adult Cardiomyocytes

(2008) Natalia López-Andrés et al.   ENDOCRINOLOGY

Aldosterone Enhances Ligand-Stimulated Nitric Oxide Production in Endothelial Cells

(2008) Akiko MUTOH et al.   HYPERTENSION RESEARCH

Aldosterone Nongenomically Produces NADPH Oxidase−Dependent Reactive Oxygen Species and Induces Myocyte Apoptosis

(2008) Hironori HAYASHI et al.   HYPERTENSION RESEARCH

EF Domains Are Sufficient for Nongenomic Mineralocorticoid Receptor Actions

(2008) Claudia Grossmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone

(2008) Catherine A. Lemarié et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Aldosterone Regulates Rapid Trafficking of Epithelial Sodium Channel Subunits in Renal Cortical Collecting Duct Cells via Protein Kinase D Activation

(2008) Victoria McEneaney et al.   MOLECULAR ENDOCRINOLOGY

Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

(2008) Shigeru Shibata et al.   NATURE MEDICINE

Aldosterone receptor sites on plasma membrane of human vascular endothelium detected by a mechanical nanosensor

(2008) L. Wildling et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Aldosterone Induces Superoxide Generation via Rac1 Activation in Endothelial Cells

(2007) Fumiko Iwashima et al.   ENDOCRINOLOGY