ICAM-1 targeting, intracellular trafficking, and functional activity of polymer nanocarriers coated with a fibrinogen-derived peptide for lysosomal enzyme replacement

Targeting cell adhesion molecules with nanoparticles using in vivo and flow-based in vitro models of atherosclerosis

(2017) Khosrow Khodabandehlou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Chitosan-Alginate Microcapsules Provide Gastric Protection and Intestinal Release of ICAM-1-Targeting Nanocarriers, Enabling GI Targeting In Vivo

(2016) Rasa Ghaffarian et al.   ADVANCED FUNCTIONAL MATERIALS

How Carrier Size and Valency Modulate Receptor-Mediated Signaling: Understanding the Link between Binding and Endocytosis of ICAM-1-Targeted Carriers

(2016) Daniel Serrano et al.   BIOMACROMOLECULES

A Comparative Study on the Alterations of Endocytic Pathways in Multiple Lysosomal Storage Disorders

(2016) Jeff Rappaport et al.   MOLECULAR PHARMACEUTICS

Lysosomal Storage Diseases: From Pathophysiology to Therapy

(2015) Giancarlo Parenti et al.   Annual Review of Medicine

Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1

(2015) Jingyan Han et al.   JOURNAL OF CONTROLLED RELEASE

A DNA Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals

(2014) Silvia Muro   ADVANCED FUNCTIONAL MATERIALS

Clathrin-Mediated Endocytosis Is Impaired in Type A–B Niemann–Pick Disease Model Cells and Can Be Restored by ICAM-1-Mediated Enzyme Replacement

(2014) Jeff Rappaport et al.   MOLECULAR PHARMACEUTICS

Delivering Nanoparticles to Lungs while Avoiding Liver and Spleen through Adsorption on Red Blood Cells

(2013) Aaron C. Anselmo et al.   ACS Nano

Enhancing Biodistribution of Therapeutic Enzymes In Vivo by Modulating Surface Coating and Concentration of ICAM-1-Targeted Nanocarriers

(2013) Janet Hsu et al.   Journal of Biomedical Nanotechnology

Vascular Immunotargeting to Endothelial Determinant ICAM-1 Enables Optimal Partnering of Recombinant scFv-Thrombomodulin Fusion with Endogenous Cofactor

(2013) Colin F. Greineder et al.   PLoS One

Emerging therapies and therapeutic concepts for lysosomal storage diseases

(2013) Thomas Kirkegaard   Expert Opinion on Orphan Drugs

Intercellular Adhesion Molecule 1 Engagement Modulates Sphingomyelinase and Ceramide, Supporting Uptake of Drug Carriers by the Vascular Endothelium

(2012) Daniel Serrano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders

(2012) Silvia Muro   Drug Delivery and Translational Research

Endothelial Targeting of Antibody-Decorated Polymeric Filomicelles

(2011) Vladimir V. Shuvaev et al.   ACS Nano

Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders

(2011) Janet Hsu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Self-assembled nanoplatform for targeted delivery of chemotherapy agents via affinity-regulated molecular interactions

(2010) Spencer Park et al.   BIOMATERIALS

Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease

(2010) Janet Hsu et al.   JOURNAL OF CONTROLLED RELEASE

Lysosomal Storage Disease: Revealing Lysosomal Function and Physiology

(2010) Emma J. Parkinson-Lawrence et al.   PHYSIOLOGY

ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells

(2009) Chuda Chittasupho et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Differential intra-endothelial delivery of polymer nanocarriers targeted to distinct PECAM-1 epitopes

(2008) C GARNACHO et al.   JOURNAL OF CONTROLLED RELEASE

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

(2008) C. Garnacho et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

PLGA Nanoparticle−Peptide Conjugate Effectively Targets Intercellular Cell-Adhesion Molecule-1

(2007) Na Zhang et al.   BIOCONJUGATE CHEMISTRY