Targeting of Streptococcus mutans Biofilms by a Novel Small Molecule Prevents Dental Caries and Preserves the Oral Microbiome

Effects of diadenylate cyclase deficiency on synthesis of extracellular polysaccharide matrix of Streptococcus mutans revisit

(2016) Xian Peng et al.   ENVIRONMENTAL MICROBIOLOGY

Streptococcus mutanscopper chaperone, CopZ, is critical for biofilm formation and competitiveness

(2016) S.S. Garcia et al.   Molecular Oral Microbiology

Short-term effects of povidone iodine and sodium fluoride therapy on plaque levels and microbiome diversity

(2016) C Reilly et al.   ORAL DISEASES

Microbiome interaction with sugar plays an important role in relapse of childhood caries

(2015) Jing Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Shape of the Dose-Response Relationship between Sugars and Caries in Adults

(2015) E. Bernabé et al.   JOURNAL OF DENTAL RESEARCH

Cyclic di-AMP mediates biofilm formation

(2015) Xian Peng et al.   MOLECULAR MICROBIOLOGY

The Effect of Fixed Orthodontic Appliances and Fluoride Mouthwash on the Oral Microbiome of Adolescents – A Randomized Controlled Clinical Trial

(2015) Jessica E. Koopman et al.   PLoS One

Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology

(2015) Lihong Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cross-fostering immediately after birth induces a permanent microbiota shift that is shaped by the nursing mother

(2015) Joseph G Daft et al.   Microbiome

Protein relative abundance patterns associated with sucrose-induced dysbiosis are conserved across taxonomically diverse oral microcosm biofilm models of dental caries

(2015) Joel D. Rudney et al.   Microbiome

A novel small molecule inhibitor of Candida albicans biofilm formation, filamentation and virulence with low potential for the development of resistance

(2015) Christopher G Pierce et al.   npj Biofilms and Microbiomes

Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions

(2013) Christina J Adler et al.   NATURE GENETICS

Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence ExpressionIn Vivo

(2012) Megan L. Falsetta et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

YidC1 and YidC2 are functionally distinct proteins involved in protein secretion, biofilm formation and cariogenicity of Streptococcus mutans

(2012) S. R. Palmer et al.   MICROBIOLOGY-SGM

Small molecule control of bacterial biofilms

(2012) Roberta J. Worthington et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Streptococcus mutans Protein Synthesis during Mixed-Species Biofilm Development by High-Throughput Quantitative Proteomics

(2012) Marlise I. Klein et al.   PLoS One

The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm

(2012) Jin Xiao et al.   PLoS Pathogens

A New Small Molecule Specifically Inhibits the Cariogenic Bacterium Streptococcus mutans in Multispecies Biofilms

(2011) Chang Liu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biology of Streptococcus mutans-Derived Glucosyltransferases: Role in Extracellular Matrix Formation of Cariogenic Biofilms

(2011) W.H. Bowen et al.   CARIES RESEARCH

Real-time quantitative polymerase chain reaction for enumeration of Streptococcus mutans from oral samples

(2011) Noel K. Childers et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Saliva microbiomes distinguish caries-active from healthy human populations

(2011) Fang Yang et al.   ISME Journal

Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents

(2010) S. A. Rogers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria

(2010) Cynthia A. Bunders et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Influence of Cranberry Proanthocyanidins on Formation of Biofilms by Streptococcus mutans on Saliva-Coated Apatitic Surface and on Dental Caries Development in vivo

(2010) H. Koo et al.   CARIES RESEARCH

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Effects of 7-Epiclusianone onStreptococcus mutansand Caries Development in Rats

(2010) Luciana Salles Branco-de-Almeida et al.   PLANTA MEDICA

Construction and Screening of a 2‐Aminoimidazole Library Identifies a Small Molecule Capable of Inhibiting and Dispersing Bacterial Biofilms across Order, Class, and Phylum

(2008) Steven A. Rogers et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Antibiofilm Activity of a Second-Generation Reverse-Amide Oroidin Library: A Structure-Activity Relationship Study

(2008) T. Eric Ballard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Characteristics of Biofilm Formation by Streptococcus mutans in the Presence of Saliva

(2008) S.-J. Ahn et al.   INFECTION AND IMMUNITY

Streptococcal Antagonism in Oral Biofilms: Streptococcus sanguinis and Streptococcus gordonii Interference with Streptococcus mutans

(2008) J. Kreth et al.   JOURNAL OF BACTERIOLOGY