Hippo Pathway: An Emerging Regulator of Craniofacial and Dental Development

The Hippo pathway in cellular reprogramming and regeneration of different organs

(2016) Iván M Moya et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

The role of Hippo signaling in tooth development

(2016) Chun-Hui Li et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

(2016) Ge Tao et al.   NATURE

αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development

(2016) Chun-Ying Li et al.   Nature Communications

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

The Hippo Pathway in Heart Development, Regeneration, and Diseases

(2015) Q. Zhou et al.   CIRCULATION RESEARCH

Yap and Taz play a crucial role in neural crest-derived craniofacial development

(2015) Jun Wang et al.   DEVELOPMENT

Hippo signaling is required for Notch-dependent smooth muscle differentiation of neural crest

(2015) L. J. Manderfield et al.   DEVELOPMENT

R331W Missense Mutation of Oncogene YAP1 Is a Germline Risk Allele for Lung Adenocarcinoma With Medical Actionability

(2015) Hsuan-Yu Chen et al.   JOURNAL OF CLINICAL ONCOLOGY

YAP Regulates the Expression ofHoxa1andHoxc13in Mouse and Human Oral and Skin Epithelial Tissues

(2015) Ming Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice

(2015) Ying Tian et al.   Science Translational Medicine

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

Heterozygous Loss-of-Function Mutations in YAP1 Cause Both Isolated and Syndromic Optic Fissure Closure Defects

(2014) Kathleen A. Williamson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model

(2014) Zhiqiang Lin et al.   CIRCULATION RESEARCH

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

(2014) X. Varelas   DEVELOPMENT

Notch and Hippo Converge on Cdx2 to Specify the Trophectoderm Lineage in the Mouse Blastocyst

(2014) Teresa Rayon et al.   DEVELOPMENTAL CELL

YAP Overexpression Affects Tooth Morphogenesis and Enamel Knot Patterning

(2014) M. Liu et al.   JOURNAL OF DENTAL RESEARCH

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation

(2014) Zhiqiang Lin et al.   Stem Cell Research

A neonatal blueprint for cardiac regeneration

(2014) Enzo R. Porrello et al.   Stem Cell Research

Spatial Organization of Hippo Signaling at the Plasma Membrane Mediated by the Tumor Suppressor Merlin/NF2

(2013) Feng Yin et al.   CELL

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development

(2013) Evan R Barry et al.   CURRENT OPINION IN CELL BIOLOGY

Hippo signaling impedes adult heart regeneration

(2013) T. Heallen et al.   DEVELOPMENT

What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease

(2013) Joshua T. Morgan et al.   EXPERIMENTAL EYE RESEARCH

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

(2013) Darjus Felix Tschaharganeh et al.   GASTROENTEROLOGY

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crossroads of Wnt and Hippo in epithelial tissues

(2013) Ilenia Bernascone et al.   TRENDS IN CELL BIOLOGY

LATS2 Suppresses Oncogenic Wnt Signaling by Disrupting β-Catenin/BCL9 Interaction

(2013) Jiong Li et al.   Cell Reports

Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling

(2012) Fa-Xing Yu et al.   CELL

Role of TAZ as Mediator of Wnt Signaling

(2012) Luca Azzolin et al.   CELL

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)

(2012) J.-S. Mo et al.   GENES & DEVELOPMENT

Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury

(2012) Dominic P. Del Re et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy

(2012) A. von Gise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila

(2011) B. G. Fernandez et al.   DEVELOPMENT

Hippo pathway regulation by cell morphology and stress fibers

(2011) K.-I. Wada et al.   DEVELOPMENT

Modulating F-actin organization induces organ growth by affecting the Hippo pathway

(2011) Leticia Sansores-Garcia et al.   EMBO JOURNAL

A kinase shRNA screen links LATS2 and the pRB tumor suppressor

(2011) K. Tschop et al.   GENES & DEVELOPMENT

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size

(2011) M. Xin et al.   Science Signaling

Coordinating developmental signaling: novel roles for the Hippo pathway

(2011) Xaralabos Varelas et al.   TRENDS IN CELL BIOLOGY

LATS tumor suppressor: A new governor of cellular homeostasis

(2010) Stacy Visser et al.   CELL CYCLE

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor

(2010) Liwen Li et al.   GENE EXPRESSION PATTERNS

Structural and functional analysis of the YAP-binding domain of human TEAD2

(2010) W. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

A New Kid on the TGFβ Block: TAZ Controls Smad Nucleocytoplasmic Shuttling

(2008) Katharine H. Wrighton et al.   DEVELOPMENTAL CELL

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

(2008) Xaralabos Varelas et al.   NATURE CELL BIOLOGY