Article
Biotechnology & Applied Microbiology
V. S. Shadrin, A. V. Machulin, L. V. Dorofeeva, S. V. Chernyshov, G. V. Mikoulinskaia
Summary: The study investigated the antibacterial specificity and effect of endolysins from colibacteriophages RB43, RB49, and T5 on diverse bacteria at different growth stages, peptidoglycan structures, and antibiotic resistances. The research found that these endolysins have a wide spectrum of antibacterial action, selectively degrading bacterial cell walls and showing promise for potential biotechnological applications.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Engineering, Environmental
Ming Zhang, Beilei Yu, Tao Xu, Daoyong Zhang, Zhimin Qiang, Xiangliang Pan
Summary: This study investigates the use of flexibly-functionalized microbubbles to simultaneously capture and inactivate/oxidize antibiotic resistant bacteria (ARB) and cell-free antibiotic resistance genes (ARGs) in water. The results show that functionalized microbubbles can effectively remove ARB and ARGs, and have good performance in wastewater treatment.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Xiaoqing Meng, Hua Li, Su Yan, Zengping Ning, Quan Yuan, Chengshuai Liu, Lixiang Zhou, Guanyu Zheng
Summary: The present study found that pre-acidification greatly promoted the inactivation of a multi-drug resistant bacterium and the degradation of carried antibiotic resistance genes (ARGs) in wastewater. Pre-acidification led to cell lysis and the release of ARGs, which were then degraded by the generated radicals. This study highlights the importance of efficiently lysing ARB cells to promote the degradation of carried ARGs and reduce antibiotic resistance in wastewater.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Karol Ulatowski, Kamil Wierzchowski, Julia Fiuk, Pawel Sobieszuk
Summary: Nanobubbles can enhance the growth of microorganisms and higher organisms, but their effects vary depending on the gas used. This study found that nanobubbles positively impact the proliferation and metabolic activity of L929 cells, but inhibit the growth of HL-60 cells. These findings have potential implications for enhancing cell growth in animal or human cultures.
Editorial Material
Biochemistry & Molecular Biology
Yupeng Wang, Feng Shao
Summary: The study identified NINJ1 as a mediator of plasma membrane rupture following programmed cell death, challenging the previous notion that this event was passive.
Review
Fisheries
Wenxing Zhu, Yali Wei, Zengmei Li, Guoxiang Lin, Feifei Han, Lujiang Hao, Jiaqiang Wu, Xinli Liu, Yuyu Zhang
Summary: Research on fish bacterial vaccines is gaining attention, with bacterial ghosts as novel vaccine candidates attracting interest for their potential in enhancing immune responses.
Article
Biochemistry & Molecular Biology
Martynas Maciulevicius, Diana Navickaite, Sonam Chopra, Baltramiejus Jakstys, Saulius Satkauskas
Summary: Research has shown that different calcium concentrations affect cell membrane permeability and cell viability during sonoporation, with ultrasound-microbubble cavitation playing a significant role. The study also indicates that inertial cavitation activities are directly involved in calcium delivery via sonoporation, leading to rapid cell death.
Article
Chemistry, Analytical
Mian Yang, Jorvani Cruz Villarreal, Nethmi Ariyasinghe, Rory Kruithoff, Robert Ros, Alexandra Ros
Summary: Advancements in single-cell analysis technologies are crucial for characterizing cells, studying cell biology, drug design, and cancer diagnosis and treatment. Current approaches using fluorescent antibody-binding technology are limited by high background and cross-talk from fluorescent labels, highlighting the need for novel label-free methods.
ANALYTICAL CHEMISTRY
(2021)
Article
Plant Sciences
Madhuni Madhushika Wijesooriya, Kanaji Masakorala, Shirani Manel Kumari Widana Gamage
Summary: This study aimed to isolate and characterize cyanolytic bacterial strains antagonistic against filamentous cyanobacteria. The isolated Pseudomonas fluorescens strain BG-E showed high cyanolytic activity against Pseudanabaena sp. LW2 and Pseudanabaena lonchoides LW1, but it was unable to degrade MC-LR cyanotoxin.
JOURNAL OF PHYCOLOGY
(2023)
Article
Food Science & Technology
Guohua Xia, Ye Li, Huihui Tao, Long Zhang, Jin Zhang, Huan Yang, Abdullateef Taiye Mustapha, Cunshan Zhou
Summary: This study further explores the inactivation mechanism of catalytic infrared (CIR) technology against Pseudomonas aeruginosa in green Sichuan pepper, finding that it mainly acts on the cell membrane to simultaneously destroy the cell membrane, inhibit swimming motility, and cause membrane dysfunction.
Editorial Material
Chemistry, Multidisciplinary
Kristie Darrah, Alexander Deiters
Summary: The light-induced lysis of red blood cell carriers offers a delivery strategy for protein therapeutics with precise spatiotemporal control.
ACS CENTRAL SCIENCE
(2021)
Article
Chemistry, Analytical
Mei-yan Wu, Wen-wei Li, Graham Christie, Peter Setlow, Yong-qing Li
Summary: Using Raman tweezers and live-cell phase-contrast microscopy, this study characterized the lysis process of individual Bacillus subtilis cells carrying PBSX prophage during spores' germination, outgrowth, and vegetative growth. The findings showed that nucleic acid intensities in induced cultures decreased rapidly after prophage induction, with a delay before cell burst, and the latent time and burst time varied in cell populations under different culture conditions.
ANALYTICAL CHEMISTRY
(2021)
Article
Oncology
Lisa A. King, Elisa C. Toffoli, Myrthe Veth, Victoria Iglesias-Guimarais, Manon C. Slot, Derk Amsen, Rieneke van de Ven, Sarah Derks, Marieke F. Fransen, Jurriaan B. Tuynman, Thilo Riedl, Rob C. Roovers, Anton E. P. Adang, Jurjen M. Ruben, Paul W. H. I. Parren, Tanja D. de Gruijl, Hans J. van der Vliet
Summary: This study assessed the antitumor activity and safety of a bispecific antibody that activates Vy9V82 T cells. In vitro, in vivo, and ex vivo experiments were conducted, and safety was evaluated in nonhuman primates. The findings demonstrated the potential of the antibody to activate Vy9V82 T cells for antitumor activity and its acceptable safety profile, providing a solid basis for further testing in patients with EGFR-positive malignancies.
CANCER IMMUNOLOGY RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Mike Bismuth, Michal Eck, Tali Ilovitsh
Summary: Ultrasound insonation of microbubbles can form transient pores in cell membranes, which can be utilized to deliver non-permeable molecules to cells. By reducing the size of microbubbles to the nanometer range, the extravasation of nanobubbles into tumors can be enhanced, providing a noninvasive sonoporation platform. Coupling nanobubbles with low frequency ultrasound can achieve high amplitude oscillations, facilitating low energy sonoporation of cancer cells. This method offers potential for noninvasive cancer treatment and gene therapy applications.
Article
Multidisciplinary Sciences
Richard Bauer, Katharina Hoenes, Tobias Meurle, Martin Hessling, Barbara Spellerberg
Summary: This study compared the cytotoxicity of violet and blue light on different cell types with the inactivation effect on ESKAPE pathogens. It was found that visible light under certain conditions could significantly reduce viable bacteria without causing cytotoxicity to cells, supporting its potential use as an antimicrobial agent in clinical settings.
SCIENTIFIC REPORTS
(2021)
Article
Energy & Fuels
Pratik D. Desai, Michael Turley, Richard Robinson, William B. Zimmerman
Summary: With 2% of the world's total energy output used for ammonia production, the remediation and recovery problem is a daunting task. However, hot microbubble stripping has shown to be more effective in removing ammonia from dilute solutions, with higher separation efficiency and mass transfer coefficients than conventional methods.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2022)
Article
Engineering, Chemical
William B. Zimmerman
Summary: Zimmerman developed a theory on additional convection of latent heat by microbubbles, and explored systematic errors and uncertainties concerning the Mpemba effect. The study found that under certain conditions, the endogenous source of microbubbles is reasonable.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Agricultural Engineering
Tito Francisco Ianda, Ricardo de Araujo Kalid, Lucas Bonfim Rocha, Antonio Domingos Padula, William B. Zimmerman
Summary: This research examines the feasibility of microalgae biodiesel production in Guinea-Bissau through technoeconomic analysis. The simulations show that the cost of producing microalgae biodiesel is competitive and has potential for scaling up.
BIOMASS & BIOENERGY
(2022)
Article
Engineering, Chemical
Ali R. Mulakhudair, Mahmood K. H. Al-Mashhadani, Rungrote Kokoo
Summary: The study of design and simulation of a gaslift bioreactor highlights the importance of addressing oxygen limitation in dense cultures, resulting in a 40.5% increase in biomass production compared to conventional systems suffering from oxygen depletion.
CHEMICAL ENGINEERING & TECHNOLOGY
(2022)
Article
Mechanics
Richard Hodgkinson, Stephen T. Chaffin, William B. J. Zimmerman, Chris Holland, Jonathan R. Howse
Summary: The effect of extensional flow on the apparent shear viscosity of a viscoelastic polymer solution is studied in this work. By using a novel flow configuration, the researchers directly measure the effect and find that shear thinning is enhanced by parallel extensional flow and reduced by perpendicular extensional flow. The commonly used models show different levels of agreement with the experimental data, with the Giesekus model providing a better qualitative description.
JOURNAL OF RHEOLOGY
(2022)
Article
Engineering, Chemical
Fahed Javed, William B. Zimmerman, Tahir Fazal, Ainy Hafeez, Maria Mustafa, Naim Rashid, Fahad Rehman
Summary: A new heterogeneous catalyst was developed by modifying a metal-organic framework with biomaterials and integrating it with microbubble mediated mass transfer technology. The catalyst achieved high conversion and reaction rate, and showed good stability.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2023)
Article
Energy & Fuels
Talha Istkhar, Ainy Hafeez, Fahad Javed, Tahir Fazal, Faisal Ahmad, Arif Hussain, William B. J. Zimmerman, Fahad Rehman
Summary: The current study explores microbubble mediated reactive distillation to improve mass transfer, conversion, and reaction rate. Methyl acetate production was investigated as a case study, showing significantly higher conversion compared to previous studies. Response Surface Methodology (RSM) and Gated Recurrent Unit (GRU) models were used to analyze parameter correlations and predict responses, with GRU proving to be more robust and reliable than RSM.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2023)
Article
Microbiology
Ali R. Mulakhudair, Mariam Sabah Naser, Amal Akour, Almurtadha Mula Kh
Summary: As the COVID-19 pandemic severely affects the health systems of multiple countries, it has become necessary to evaluate disease severity and its correlation with clinical and biochemical markers. These predictors can assist in the diagnosis and treatment of COVID-19 and future respiratory infections. This cross-sectional study explored the association between inflammatory markers and chronic conditions with computed tomography (CT) severity score and D-dimer as a surrogate marker. The results indicated positive and significant correlations between inflammatory markers, age, and D-dimer, but inverse correlations with oxygen saturation (SPO2). The CT score showed a similar pattern, except for C-reactive protein. Vaccinations had a positive impact on CT severity score and Neutrophil to lymphocyte ratio. These findings affirm the importance of vaccination, particularly for patients with chronic diseases, as recommended by the WHO and other international organizations. The implications of these results are significant and provide insights for managing and evaluating COVID-19 patients in Iraqi healthcare facilities.
CURRENT MICROBIOLOGY
(2023)
Review
Chemistry, Physical
Pratik D. Desai, William B. Zimmerman
Summary: Microbubble dispersions are commonly used in industrial applications, and the wetting properties of microbubble generation devices have a significant influence on bubble size distribution. Recent studies have shown that wetting is an important factor in microbubble performance. It is recommended to assess the influence of wetting based on mechanisms/devices where wetting effects have been demonstrated.
CURRENT OPINION IN COLLOID & INTERFACE SCIENCE
(2023)
Article
Engineering, Chemical
Thomas D. Holmes, Bryony C. Moody, William B. J. Zimmerman
Summary: A plasma chemical reaction system can be accurately represented using a directed bipartite variable-relationship graph to analyze node influence and determine improved condition sequencing for a target outcome. A novel graph algorithm (OCARINA) was adapted for this graph and two conventional node-influence measures were also tested. The evaluation of the electron energy node influence using three different methods showed that OCARINA closely matched the simulation results for O-3 concentrations.
PLASMA CHEMISTRY AND PLASMA PROCESSING
(2023)
Article
Chemistry, Multidisciplinary
Dhia Ibrahim Jerro Al-Bedrani, Ali R. Mulakhudair, Jasim M. S. Al-Saadi
Summary: This study aimed to investigate the effect of adding sodium pyrophosphate (SSP salt) to milk used for yogurt production on pH and rheological properties, showing that pre-heat treatment addition had a greater impact.
EGYPTIAN JOURNAL OF CHEMISTRY
(2022)
Article
Engineering, Chemical
Fahed Javed, William B. Zimmerman, Tahir Fazal, Ainy Hafeez, Maria Mustafa, Naim Rashid, Fahad Rehman
Summary: A new heterogeneous catalyst, Bio-MOF complexed with an ionic liquid ([HMIM][HSO4]/Bio-MOF), has been synthesized and integrated with microbubble-mediated mass transfer technology to achieve a high conversion rate of biodiesel production. The catalyst demonstrates superior reactivity and stability.
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2022)
Article
Biotechnology & Applied Microbiology
Fahed Javed, Muhammad Rizwan, Maryam Asif, Shahzad Ali, Rabya Aslam, Muhammad Sarfraz Akram, William B. Zimmerman, Fahad Rehman
Summary: This study focuses on the conversion of waste resources into biodiesel using a bifunctional catalyst and microbubble-mediated mass transfer technology. The results demonstrate a high conversion rate and stability using the 7% Sr/ZrO2 catalyst. Additionally, the one-step process reduces energy consumption, improves cost-efficiency, and simplifies the production process.
BIOENGINEERING-BASEL
(2022)
Article
Engineering, Chemical
Atheer M. G. Al-Yaqoobi, William B. Zimmerman
Summary: Controlling the size of bubbles is crucial for enhancing transport performance in gas-liquid systems. This study investigates the role of surface wettability on bubble size using the Washburn method. The results show that liquids with small contact angles produce smaller bubbles compared to liquids with higher contact angles. The study demonstrates the viability of the Washburn method in characterizing wettability and suggests that carefully choosing a diffuser material with better wettability can significantly reduce bubble size.
CHEMICAL AND PROCESS ENGINEERING-INZYNIERIA CHEMICZNA I PROCESOWA
(2022)