Dexamethasone suppresses JMJD3 gene activation via a putative negative glucocorticoid response element and maintains integrity of tight junctions in brain microvascular endothelial cells

Jmjd3 mediates blood–spinal cord barrier disruption after spinal cord injury by regulating MMP-3 and MMP-9 expressions

(2016) Jee Y. Lee et al.   NEUROBIOLOGY OF DISEASE

Progesterone attenuates thrombin-induced endothelial barrier disruption in the brain endothelial cell line bEnd.3: The role of tight junction proteins and the endothelial protein C receptor

(2015) Jeong Hun Lee et al.   BRAIN RESEARCH

Dexamethasone Potentiates in Vitro Blood-Brain Barrier Recovery after Primary Blast Injury by Glucocorticoid Receptor-Mediated Upregulation of ZO-1 Tight Junction Protein

(2015) Christopher D Hue et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of TNF-α protects in vitro brain barrier from ischaemic damage

(2015) Zuraidah Abdullah et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

17β-Estradiol Ameliorates Tight Junction Disruption via Repression of MMP Transcription

(2015) Wonho Na et al.   MOLECULAR ENDOCRINOLOGY

GR SUMOylation and formation of an SUMO-SMRT/NCoR1-HDAC3 repressing complex is mandatory for GC-induced IR nGRE-mediated transrepression

(2015) Guoqiang Hua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid-induced tethered transrepression requires SUMOylation of GR and formation of a SUMO-SMRT/NCoR1-HDAC3 repressing complex

(2015) Guoqiang Hua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects

(2015) Reiner F. Haseloff et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Vitamin D Prevents Hypoxia/Reoxygenation-Induced Blood-Brain Barrier Disruption via Vitamin D Receptor-Mediated NF-kB Signaling Pathways

(2015) Soonmi Won et al.   PLoS One

Matrix Metalloproteinase-3 Promotes Early Blood–Spinal Cord Barrier Disruption and Hemorrhage and Impairs Long-Term Neurological Recovery after Spinal Cord Injury

(2014) Jee Youn Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Jmjd3-mediated epigenetic regulation of inflammatory cytokine gene expression in serum amyloid A-stimulated macrophages

(2014) Qian Yan et al.   CELLULAR SIGNALLING

The localization of histone H3K27me3 demethylase Jmjd3 is dynamically regulated

(2014) Yasunao F Kamikawa et al.   Epigenetics

Mechanisms of transcriptional activation of the mouse claudin-5 promoter by estrogen receptor alpha and beta

(2014) Malgorzata Burek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoids and endothelial cell barrier function

(2013) Ellaine Salvador et al.   CELL AND TISSUE RESEARCH

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

(2013) Piotr Przanowski et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Blood-brain barrier and traumatic brain injury

(2013) José Luís Alves   JOURNAL OF NEUROSCIENCE RESEARCH

Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis

(2013) Su Zhang et al.   MEDIATORS OF INFLAMMATION

Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements

(2013) Sivapriya Ramamoorthy et al.   MOLECULAR AND CELLULAR BIOLOGY

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications

(2013) E. Cristante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Acute Ischemic Stroke

(2013) Shaheen E. Lakhan et al.   Frontiers in Neurology

Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury

(2012) Jee Y. Lee et al.   JOURNAL OF NEUROCHEMISTRY

Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury

(2012) Kwanghyun Lee et al.   JOURNAL OF NEUROCHEMISTRY

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Matrix metalloproteinase-2 or -9 deletions protect against hemorrhagic transformation during early stage of cerebral ischemia and reperfusion

(2012) Y. Suofu et al.   NEUROSCIENCE

Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

(2011) Milan Surjit et al.   CELL

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

(2011) Muhammad Aslam et al.   CYTOKINE

Occludin: One Protein, Many Forms

(2011) P. M. Cummins   MOLECULAR AND CELLULAR BIOLOGY

Hydrocortisone Enhances the Function of the Blood-Nerve Barrier Through the Up-Regulation of Claudin-5

(2011) Yoko Kashiwamura et al.   NEUROCHEMICAL RESEARCH

RhoA and NF-κB are involved in lipopolysaccharide-induced brain microvascular cell line hyperpermeability

(2011) F. He et al.   NEUROSCIENCE

Blood–Brain Barrier Breakdown in Acute and Chronic Cerebrovascular Disease

(2011) Yi Yang et al.   STROKE

Glucocorticoid Insensitivity at the Hypoxic Blood–Brain Barrier Can Be Reversed by Inhibition of the Proteasome

(2011) Christoph Kleinschnitz et al.   STROKE

Tight Junction–associated MARVEL Proteins MarvelD3, Tricellulin, and Occludin Have Distinct but Overlapping Functions

(2010) David R. Raleigh et al.   MOLECULAR BIOLOGY OF THE CELL

Control of the Blood-Brain Barrier by Glucocorticoids and the Cells of the Neurovascular Unit

(2009) Susanne Kröll et al.   Annals of the New York Academy of Sciences

TIMP-3: A novel target for glucocorticoid signaling at the blood–brain barrier

(2009) Christoph Hartmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein

(2009) Y. Suzuki et al.   BLOOD

Caveolae-mediated Internalization of Occludin and Claudin-5 during CCL2-induced Tight Junction Remodeling in Brain Endothelial Cells

(2009) Svetlana M. Stamatovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element

(2008) Edward A. Felinski et al.   EXPERIMENTAL EYE RESEARCH

Glucocorticoids Increase VE-Cadherin Expression and Cause Cytoskeletal Rearrangements in Murine Brain Endothelial cEND Cells

(2008) Kinga G Blecharz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice

(2008) B. W. McColl et al.   JOURNAL OF NEUROSCIENCE

Differential effects of hydrocortisone and TNFα on tight junction proteins in anin vitromodel of the human blood-brain barrier

(2008) Carola Förster et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glucocorticoids regulate the human occludin gene through a single imperfect palindromic glucocorticoid response element

(2008) Nina Harke et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cloning and characterization of the murine claudin-5 promoter

(2008) Malgorzata Burek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Loss of Occludin Affects Tricellular Localization of Tricellulin

(2008) Junichi Ikenouchi et al.   MOLECULAR BIOLOGY OF THE CELL

Expression of Claudin-1, Claudin-3 and Claudin-5 in human blood–brain barrier mimicking cell line ECV304 is inducible by glioma-conditioned media

(2008) Winfried Neuhaus et al.   NEUROSCIENCE LETTERS