Lipid profiling of parkin -mutant human skin fibroblasts

Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein

(2016) Coralie Di Scala et al.   Scientific Reports

MALDI-TOF MS Lipid Profiles of Cytochrome c Oxidases: Cardiolipin Is Not an Essential Component of the Paracoccus denitrificans Oxidase

(2015) Rita Vitale et al.   BIOCHEMISTRY

Altered protein expression pattern in skin fibroblasts from parkin -mutant early-onset Parkinson's disease patients

(2015) Rosa Lippolis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Major Alterations of Phosphatidylcholine and Lysophosphotidylcholine Lipids in the Substantia Nigra Using an Early Stage Model of Parkinson’s Disease

(2015) Kyle Farmer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cardiolipin fingerprinting of leukocytes by MALDI-TOF/MS as a screening tool for Barth syndrome

(2015) Roberto Angelini et al.   JOURNAL OF LIPID RESEARCH

Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease

(2015) Seon-Heui Cha et al.   Molecular Neurodegeneration

No evidence for substrate accumulation in Parkinson brains withGBAmutations

(2015) Matthew E. Gegg et al.   MOVEMENT DISORDERS

Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease

(2014) Anna Ferretta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cytoskeletal Alterations and Biomechanical Properties of parkin-Mutant Human Primary Fibroblasts

(2014) Daniele Vergara et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

A fast method for the determination of the PC/LPC ratio in intact serum by MALDI-TOF MS: An easy-to-follow lipid biomarker of inflammation

(2014) Roberto Angelini et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Acceleration of α-Synuclein Aggregation by Exosomes

(2014) Marie Grey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy

(2014) R. M. Ivatt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis

(2014) David C. Schöndorf et al.   Nature Communications

Plasma Ceramide and Glucosylceramide Metabolism Is Altered in Sporadic Parkinson's Disease and Associated with Cognitive Impairment: A Pilot Study

(2013) Michelle M. Mielke et al.   PLoS One

Parkinsonism Due to Mutations in PINK1, Parkin, and DJ-1 and Oxidative Stress and Mitochondrial Pathways

(2013) M. R. Cookson   Cold Spring Harbor Perspectives in Medicine

Considerations Regarding the Etiology and Future Treatment of Autosomal Recessive Versus Idiopathic Parkinson Disease

(2012) Tohru Kitada et al.   Current Treatment Options in Neurology

PINK1- and Parkin-mediated mitophagy at a glance

(2012) Seok Min Jin et al.   JOURNAL OF CELL SCIENCE

Lipidomics of intact mitochondria by MALDI-TOF/MS

(2012) Roberto Angelini et al.   JOURNAL OF LIPID RESEARCH

The link between the GBA gene and parkinsonism

(2012) Ellen Sidransky et al.   LANCET NEUROLOGY

Primary Skin Fibroblasts as a Model of Parkinson's Disease

(2012) Georg Auburger et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial defect and PGC-1α dysfunction in parkin-associated familial Parkinson's disease

(2011) Consiglia Pacelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies

(2011) Joseph R. Mazzulli et al.   CELL

Cardiolipin content in mitochondria from cultured skin fibroblasts harboring mutations in the mitochondrial ATP6 gene

(2011) Mohammed El-Hafidi et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Parkin reinvents itself to regulate fatty acid metabolism by tagging CD36

(2011) Nada A. Abumrad et al.   JOURNAL OF CLINICAL INVESTIGATION

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

(2011) Kye-Young Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular pathways in sporadic PD

(2011) Enza Maria Valente et al.   PARKINSONISM & RELATED DISORDERS

Lipid Pathway Alterations in Parkinson's Disease Primary Visual Cortex

(2011) Danni Cheng et al.   PLoS One

Gangliosides' analysis by MALDI-ion mobility MS

(2010) Shelley N. Jackson et al.   ANALYST

Oxidative stress in skin fibroblasts cultures from patients with Parkinson's disease

(2010) Pilar del Hoyo et al.   BMC Neurology

Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

(2010) Joo-Yong Lee et al.   JOURNAL OF CELL BIOLOGY

MALDI-TOF/MS analysis of archaebacterial lipids in lyophilized membranes dry-mixed with 9-aminoacridine

(2010) Roberto Angelini et al.   JOURNAL OF LIPID RESEARCH

Sphingolipids: the nexus between Gaucher disease and insulin resistance

(2010) Maria Fuller   Lipids in Health and Disease

Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders

(2010) Marco Piccinini et al.   MOLECULAR NEUROBIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutant Parkin Impairs Mitochondrial Function and Morphology in Human Fibroblasts

(2010) Anne Grünewald et al.   PLoS One

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

(2009) Juliane Neumann et al.   BRAIN

Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

(2009) Oliver Rothfuss et al.   HUMAN MOLECULAR GENETICS

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

(2009) Hui Xiong et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial function and morphology are impaired inparkin-mutant fibroblasts

(2008) Heather Mortiboys et al.   ANNALS OF NEUROLOGY

Glucocerebrosidase Gene Mutations

(2008) Ignacio F. Mata et al.   ARCHIVES OF NEUROLOGY

The role of glycosphingolipid metabolism in the developing brain

(2008) Robert K. Yu et al.   JOURNAL OF LIPID RESEARCH