Triptolide prevents extracellular matrix accumulation in experimental diabetic kidney disease by targeting microRNA-137/Notch1 pathway

MicroRNA-137 suppresses tongue squamous carcinoma cell proliferation, migration and invasion

(2016) Lanying Sun et al.   CELL PROLIFERATION

Triptolide Induces Cell Killing in Multidrug-Resistant Tumor Cells via CDK7/RPB1 Rather than XPB or p44

(2016) Jun-Mei Yi et al.   MOLECULAR CANCER THERAPEUTICS

Effect of acid-sensing ion channel 1a on the process of liver fibrosis under hyperglycemia

(2015) Huan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A MicroRNA Signature in Gestational Diabetes Mellitus Associated with Risk of Macrosomia

(2015) Jiandong Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Notch1 and Notch2 in Podocytes Play Differential Roles During Diabetic Nephropathy Development

(2015) Mariya T. Sweetwyne et al.   DIABETES

Anti-inflammatory effects of triptolide on IgA nephropathy in rats

(2015) Liyu He et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Inhibition of Cancer Angiogenesis Using Triptolide Nanoparticles

(2015) Cheng Wang et al.   Journal of Biomedical Nanotechnology

Phosphonooxymethyl Prodrug of Triptolide: Synthesis, Physicochemical Characterization, and Efficacy in Human Colon Adenocarcinoma and Ovarian Cancer Xenografts

(2015) Satish Patil et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study

(2015) Shanshan Liu et al.   BMC Nephrology

A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets

(2015) Ruli Gao et al.   Oncotarget

miR-137 Controls Proliferation and Differentiation of Human Adipose Tissue Stromal Cells

(2014) Keun Koo Shin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MiR-135a promotes renal fibrosis in diabetic nephropathy by regulating TRPC1

(2014) Feng He et al.   DIABETOLOGIA

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development

(2013) S. C. Boyle et al.   DEVELOPMENT

Regulation of Breast Cancer and Bone Metastasis by MicroRNAs

(2013) S. Vimalraj et al.   DISEASE MARKERS

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A

(2013) Kristina Althoff et al.   INTERNATIONAL JOURNAL OF CANCER

Triptolide reverses hypoxia-induced epithelial-mesenchymal transition and stem-like features in pancreatic cancer by NF-κB downregulation

(2013) Li Liu et al.   INTERNATIONAL JOURNAL OF CANCER

Treatment of diabetic nephropathy with Tripterygium wilfordii Hook F extract: a prospective, randomized, controlled clinical trial

(2013) Yongchun Ge et al.   Journal of Translational Medicine

NF-κB inhibition significantly upregulates the norepinephrine transporter system, causes apoptosis in pheochromocytoma cell lines and prevents metastasis in an animal model

(2012) Karel Pacak et al.   INTERNATIONAL JOURNAL OF CANCER

Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappa B signaling pathway in vitro

(2012) Xiao-Nan Wang et al.   Chinese Journal of Cancer

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes

(2011) Karly C. Sourris et al.   FREE RADICAL BIOLOGY AND MEDICINE

Suppression of microRNA-29 Expression by TGF- 1 Promotes Collagen Expression and Renal Fibrosis

(2011) B. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Modulation of Notch-1 Signaling Alleviates Vascular Endothelial Growth Factor–Mediated Diabetic Nephropathy

(2010) Chun-Liang Lin et al.   DIABETES

Meta-Analysis of Tripterygium Wilfordii Hook F in the Immunosuppressive Treatment of IgA Nephropathy

(2010) Yi-Zhi Chen et al.   INTERNAL MEDICINE

Triptolide reduces proteinuria in experimental membranous nephropathy and protects against C5b-9-induced podocyte injury in vitro

(2010) Zhao-Hong Chen et al.   KIDNEY INTERNATIONAL

Triptolide Reduces Cystogenesis in a Model of ADPKD

(2008) S. J. Leuenroth et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteinuria in diabetic kidney disease: A mechanistic viewpoint

(2008) J.A. Jefferson et al.   KIDNEY INTERNATIONAL