MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A

Breaking the LSD1/KDM1A Addiction: Therapeutic Targeting of the Epigenetic Modifier in AML

(2012) Alyson A. Lokken et al.   CANCER CELL

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

(2012) Marilena V. Iorio et al.   EMBO Molecular Medicine

LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression

(2012) Jan J Molenaar et al.   NATURE GENETICS

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia

(2012) Tino Schenk et al.   NATURE MEDICINE

Inhibition of Neuroblastoma Tumor Growth by Targeted Delivery of MicroRNA-34a Using Anti-Disialoganglioside GD2 Coated Nanoparticles

(2012) Amanda Tivnan et al.   PLoS One

MicroRNA-34a is a potent tumor suppressor molecule in vivo in neuroblastoma

(2011) Amanda Tivnan et al.   BMC CANCER

MicroRNA-542-5p as a novel tumor suppressor in neuroblastoma

(2011) Isabella Bray et al.   CANCER LETTERS

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

(2011) GuoQiang Sun et al.   Nature Communications

Epigenetic Silencing of miR-137 Is an Early Event in Colorectal Carcinogenesis

(2010) F. Balaguer et al.   CANCER RESEARCH

Neuroblastoma: Biology, Prognosis, and Treatment

(2010) Julie R. Park et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

(2010) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

(2010) Pieter Mestdagh et al.   MOLECULAR CELL

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

(2010) Johannes H. Schulte et al.   NUCLEIC ACIDS RESEARCH

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

H3K4 dimethylation in hepatocellular carcinoma is rare compared with other hepatobiliary and gastrointestinal carcinomas and correlates with expression of the methylase Ash2 and the demethylase LSD1

(2009) Christian Magerl et al.   HUMAN PATHOLOGY

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

MicroRNAs in the pathogenesis of neuroblastoma

(2008) Johannes H. Schulte et al.   CANCER LETTERS

MicroRNA-137 Targets Microphthalmia-Associated Transcription Factor in Melanoma Cell Lines

(2008) L. T. Bemis et al.   CANCER RESEARCH

Exploration of Tumor-Suppressive MicroRNAs Silenced by DNA Hypermethylation in Oral Cancer

(2008) K.-i. Kozaki et al.   CANCER RESEARCH

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

MYCN regulates oncogenic MicroRNAs in neuroblastoma

(2007) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of KIT and PDGFR is associated with a good prognosis in neuroblastoma

(2007) Akira Shimada et al.   PEDIATRIC BLOOD & CANCER