Clinical opportunities and challenges in targeting tumour dormancy

RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration

(2012) Neveen Said et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Significance and Molecular Characteristics of Circulating Tumor Cells and Circulating Tumor Microemboli in Patients With Small-Cell Lung Cancer

(2012) Jian-Mei Hou et al.   JOURNAL OF CLINICAL ONCOLOGY

Residual dormant cancer stem-cell foci are responsible for tumor relapse after antiangiogenic metronomic therapy in hepatocellular carcinoma xenografts

(2012) Ines Martin-Padura et al.   LABORATORY INVESTIGATION

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

(2012) O. Straume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors

(2011) Xin Lu et al.   CANCER CELL

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

Development of Novel Therapeutics Targeting the Urokinase Plasminogen Activator Receptor (uPAR) and Their Translation Toward the Clinic

(2011) Andrew P. Mazar et al.   CURRENT PHARMACEUTICAL DESIGN

Genomic analysis of circulating cell-free DNA infers breast cancer dormancy

(2011) J. A. Shaw et al.   GENOME RESEARCH

Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone

(2011) Aya Kobayashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors

(2011) C. Cekic et al.   JOURNAL OF IMMUNOLOGY

Tumour macrophages as potential targets of bisphosphonates

(2011) Thea L Rogers et al.   Journal of Translational Medicine

A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment

(2011) Steven Christopher Smith et al.   LANCET ONCOLOGY

Controversies in clinical cancer dormancy

(2011) J. W. Uhr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of tumor hypoxia in MUC1-positive breast carcinomas

(2011) Juliana Silva Zanetti et al.   VIRCHOWS ARCHIV

Disruption of a Quorum Sensing mechanism triggers tumorigenesis: a simple discrete model corroborated by experiments in mammary cancer stem cells

(2010) Zvia Agur et al.   Biology Direct

Breast cancer cell dormancy in bone marrow: potential therapeutic targets within the marrow microenvironment

(2010) Pranela Rameshwar   Expert Review of Anticancer Therapy

Survivin and escaping in therapy-induced cellular senescence

(2010) Qin Wang et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer

(2010) Neveen Said et al.   JOURNAL OF CLINICAL INVESTIGATION

METRONOMIC CYCLOPHOSPHAMIDE IN ELDERLY PATIENTS WITH ADVANCED, CASTRATION-RESISTANT PROSTATE CANCER

(2010) Andrea Fontana et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Transmission of donor melanoma by organ transplantation

(2010) Dirk C Strauss et al.   LANCET ONCOLOGY

Metronomic chemotherapy: new rationale for new directions

(2010) Eddy Pasquier et al.   Nature Reviews Clinical Oncology

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Probing Prokaryotic Social Behaviors with Bacterial "Lobster Traps"

(2010) J. L. Connell et al.   mBio

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

Three-Dimensional Imaging and Quantification of Both Solitary Cells and Metastases in Whole Mouse Liver by Magnetic Resonance Imaging

(2009) J. L. Townson et al.   CANCER RESEARCH

Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype

(2009) N. Almog et al.   CANCER RESEARCH

Immune cells and angiogenesis

(2009) Domenico Ribatti et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

B7-H1 up-regulation on dendritic-like leukemia cells suppresses T cell immune function through modulation of IL-10/IL-12 production and generation of Treg cells

(2009) Wei Ge et al.   LEUKEMIA RESEARCH

Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs

(2009) B. S. Marasa et al.   Science Signaling

Tumor dormancy and immunoescape 

(2008) BRUNO QUESNEL   APMIS

The role of metastasis suppressor genes in metastatic dormancy 

(2008) CHRISTINE E. HORAK et al.   APMIS

Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

(2008) D. Barkan et al.   CANCER RESEARCH

c-Jun NH2-Terminal Kinase Activating Kinase 1/Mitogen-Activated Protein Kinase Kinase 4-Mediated Inhibition of SKOV3ip.1 Ovarian Cancer Metastasis Involves Growth Arrest and p21 Up-regulation

(2008) T. Lotan et al.   CANCER RESEARCH

Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis

(2008) Jonathan Hickson et al.   CLINICAL & EXPERIMENTAL METASTASIS

Immune-mediated dormancy: an equilibrium with cancer

(2008) Michele W. L. Teng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Anti-Epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-Like Breast Tumor Cells

(2008) Anieta M. Sieuwerts et al.   JNCI-Journal of the National Cancer Institute

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metastasis: a therapeutic target for cancer

(2008) Patricia S Steeg et al.   Nature clinical practice. Oncology