Leptin induces matrix metalloproteinase 7 expression to promote ovarian cancer cell invasion by activating ERK and JNK pathways

Modes of cancer cell invasion and the role of the microenvironment

(2015) Andrew G Clark et al.   CURRENT OPINION IN CELL BIOLOGY

Leptin signaling enhances cell invasion and promotes the metastasis of human pancreatic cancer via increasing MMP-13 production

(2015) Yingchao Fan et al.   Oncotarget

Leptin-Promoted Human Extravillous Trophoblast Invasion Is MMP14 Dependent and Requires the Cross Talk Between Notch1 and PI3K/Akt Signaling1

(2014) Huayang Wang et al.   BIOLOGY OF REPRODUCTION

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

(2014) T-I Hsu et al.   ONCOGENE

Leptin-induced adhesion and invasion in colorectal cancer cell lines

(2014) KYUNG-WON YOON et al.   ONCOLOGY REPORTS

Mechanisms linking obesity and cancer

(2013) Sharon M. Louie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Adipose tissue and adipocytes support tumorigenesis and metastasis

(2013) Kristin M. Nieman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion

(2013) Zhaogang Dong et al.   CARCINOGENESIS

Obesity-associated adipokines correlate with survival in epithelial ovarian cancer

(2013) Elena S. Diaz et al.   GYNECOLOGIC ONCOLOGY

Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways

(2013) CHIACHEN CHEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Leptin promotes the proliferation and migration of human breast cancer through the extracellular-signal regulated kinase pathway

(2013) HONG-JUN YUAN et al.   Molecular Medicine Reports

Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

(2013) Elin Hadler-Olsen et al.   TUMOR BIOLOGY

Inflammation and ovarian cancer

(2012) Antonio Macciò et al.   CYTOKINE

Minireview: Human Ovarian Cancer: Biology, Current Management, and Paths to Personalizing Therapy

(2012) Ignacio Romero et al.   ENDOCRINOLOGY

Triptolide inhibits ovarian cancer cell invasion by repression of matrix metalloproteinase 7 and 19 and upregulation of E-cadherin

(2012) Hongxi Zhao et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

In vitro cell migration and invasion assays

(2012) Nina Kramer et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways

(2011) Ming-Cheng Chang et al.   BIOCHEMICAL JOURNAL

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth

(2010) Jung-Hye Choi et al.   CARCINOGENESIS

Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation

(2010) Ruben R. Gonzalez-Perez et al.   CELLULAR SIGNALLING

Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells

(2009) Vanity McMurtry et al.   CLINICAL & EXPERIMENTAL METASTASIS

Overexpression of leptin receptor predicts an unfavorable outcome in Middle Eastern ovarian cancer

(2009) Shahab Uddin et al.   Molecular Cancer

c-Jun NH2-terminal kinase mediates leptin-stimulated androgen-independent prostate cancer cell proliferation via signal transducer and activator of transcription 3 and Akt

(2008) Toshiaki Miyazaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Leptin induces migration and invasion of glioma cells through MMP-13 production

(2008) Wei-Lan Yeh et al.   GLIA