Leptin-Promoted Human Extravillous Trophoblast Invasion Is MMP14 Dependent and Requires the Cross Talk Between Notch1 and PI3K/Akt Signaling1

Divergent and Synergistic Regulation of Matrix Metalloprotease Production by Cytokines in Combination with C-C Chemokines

(2017) V.J. Richardson   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Leptin-mediated regulation of MT1-MMP localization is KIF1B dependent and enhances gastric cancer cell invasion

(2013) Zhaogang Dong et al.   CARCINOGENESIS

Aberrant Synthesis, Metabolism, and Plasma Accumulation of Circulating Estrogens and Estrogen Metabolites in Preeclampsia Implications for Vascular Dysfunction

(2013) Sheikh O. Jobe et al.   HYPERTENSION

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin

(2012) Tu'uhevaha J. Kaitu'u-Lino et al.   AMERICAN JOURNAL OF PATHOLOGY

Leptin and HER-2 are associated with gastric cancer progression and prognosis of patients

(2012) Yiting Geng et al.   BIOMEDICINE & PHARMACOTHERAPY

HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCR -selected mouse thymocytes

(2012) G. W. Wong et al.   BLOOD

Fetal Insulin and IGF-II Contribute to Gestational Diabetes Mellitus (GDM)-Associated Up-Regulation of Membrane-Type Matrix Metalloproteinase 1 (MT1-MMP) in the Human Feto-Placental Endothelium

(2012) U. Hiden et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

(2012) Anne E Chambers et al.   Reproductive Biology and Endocrinology

A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia

(2011) N. M. Hunkapiller et al.   DEVELOPMENT

MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell development

(2011) Guoxiang Jin et al.   EMBO JOURNAL

Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells

(2011) B. B. Knight et al.   ENDOCRINE-RELATED CANCER

Regulation of MT1-MMP and MMP-2 by Leptin in Cardiac Fibroblasts Involves Rho/ROCK-Dependent Actin Cytoskeletal Reorganization and Leads to Enhanced Cell Migration

(2011) Kristin Schram et al.   ENDOCRINOLOGY

Notch1 mediates uterine stromal differentiation and is critical for complete decidualization in the mouse

(2011) Yalda Afshar et al.   FASEB JOURNAL

MT1-MMP regulates the turnover and endocytosis of extracellular matrix fibronectin

(2011) F. Shi et al.   JOURNAL OF CELL SCIENCE

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

(2011) Hind Medyouf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch, IL-1 and Leptin Crosstalk Outcome (NILCO) Is Critical for Leptin-Induced Proliferation, Migration and VEGF/VEGFR-2 Expression in Breast Cancer

(2011) Shanchun Guo et al.   PLoS One

MAPK and PI3K activities are required for leptin stimulation of protein synthesis in human trophoblastic cells

(2010) Antonio Pérez-Pérez et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane-type MMPs are indispensable for placental labyrinth formation and development

(2010) L. Szabova et al.   BLOOD

Notch1and the activated NOTCH1 intracellular domain are expressed in differentiated trophoblast cells

(2010) Didem Pelin Sarikaya et al.   CELL BIOLOGY INTERNATIONAL

Intracellular Pathogen Sensor NOD2 Programs Macrophages to Trigger Notch1 Activation

(2010) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

(2010) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of leptin on cytotrophoblast proliferation and invasion

(2010) Haiyi Liu et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Dysregulation of Leptin and Testosterone Production and Their Receptor Expression in the Human Placenta with Gestational Diabetes Mellitus

(2010) P.S. Uzelac et al.   PLACENTA

Interleukin-8 (CXCL8) stimulates trophoblast cell migration and invasion by increasing levels of matrix metalloproteinase (MMP)2 and MMP9 and integrins α5 and β1

(2010) Milica Jovanović et al.   REPRODUCTION

Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia

(2009) R. Poincloux et al.   JOURNAL OF CELL SCIENCE

MT1-MMP- and Cdc42-dependent signaling co-regulate cell invasion and tunnel formation in 3D collagen matrices

(2009) Kevin E. Fisher et al.   JOURNAL OF CELL SCIENCE

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia

(2009) Sara González-García et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch activation enhances IFNγ secretion by human peripheral blood and decidual NK cells

(2009) Irit Manaster et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Oncogenic NOTCH1 Control of MYC and PI3K: Challenges and Opportunities for Anti-NOTCH1 Therapy in T-Cell Acute Lymphoblastic Leukemias and Lymphomas

(2008) T. Palomero et al.   CLINICAL CANCER RESEARCH

Increased expression and cell surface localization of MT1-MMP plays a role in stimulation of MMP-2 activity by leptin in neonatal rat cardiac myofibroblasts

(2008) Kristin Schram et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Effect of Hormones on Matrix Metalloproteinases Gene Regulation in Human Aortic Smooth Muscle Cells

(2008) Oscar H. Grandas et al.   JOURNAL OF SURGICAL RESEARCH

The role of Notch signaling in human cervical cancer: implications for solid tumors

(2008) T T Maliekal et al.   ONCOGENE

Expression Patterns of Two Serine Protease HtrA1 Forms in Human Placentas Complicated by Preeclampsia with and without Intrauterine Growth Restriction

(2008) T. Lorenzi et al.   PLACENTA