PTK6 Localized at the Plasma Membrane Promotes Cell Proliferation and MigratiOn Through Phosphorylation of Eps8

Biphasic effect of PTK7 on KDR activity in endothelial cells and angiogenesis

(2015) Won-Sik Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors

(2015) Maoyu Peng et al.   Oncotarget

Discovery of ( E )-5-(benzylideneamino)-1 H -benzo[ d ]imidazol-2(3 H )-one derivatives as inhibitors for PTK6

(2014) Hyun Jae Shim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Eps8 regulates cellular proliferation and migration of breast cancer

(2014) CHENG CHEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells

(2014) C. Schoenherr et al.   JOURNAL OF CELL SCIENCE

Identification of Human Complement Factor B as a Novel Biomarker Candidate for Pancreatic Ductal Adenocarcinoma

(2014) Min Jung Lee et al.   JOURNAL OF PROTEOME RESEARCH

Galangin and Kaempferol Suppress Phorbol-12-Myristate-13-Acetate-Induced Matrix Metalloproteinase-9 Expression in Human Fibrosarcoma HT-1080 Cells

(2014) Yu Jung Choi et al.   MOLECULES AND CELLS

PTK6 promotes degradation of c-Cbl through PTK6-mediated phosphorylation

(2013) Shin-Ae Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PTK6 Activation at the Membrane Regulates Epithelial-Mesenchymal Transition in Prostate Cancer

(2013) Y. Zheng et al.   CANCER RESEARCH

Oncogenic role of protein tyrosine kinase 7 in esophageal squamous cell carcinoma

(2013) Won-Sik Shin et al.   CANCER SCIENCE

Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer

(2013) Yu Zheng et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Novel oncoprotein EPS8: a new target for anticancer therapy

(2013) Yu-Hua Li et al.   Future Oncology

Novel Binding Partners and Differentially Regulated Phosphorylation Sites Clarify Eps8 as a Multi-Functional Adaptor

(2013) Debbie L. Cunningham et al.   PLoS One

The Cytosolic Domain of Protein-tyrosine Kinase 7 (PTK7), Generated from Sequential Cleavage by a Disintegrin and Metalloprotease 17 (ADAM17) and γ-Secretase, Enhances Cell Proliferation and Migration in Colon Cancer Cells

(2012) Hye-Won Na et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brk/PTK6 signaling in normal and cancer cell models

(2010) Julie H Ostrander et al.   CURRENT OPINION IN PHARMACOLOGY

PTK6 Inhibits Down-regulation of EGF Receptor through Phosphorylation of ARAP1

(2010) Shin-Ae Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival

(2010) Hanna Y. Irie et al.   PLoS One

Oncogenic Functions of PTK6 are Enhanced by Its Targeting to Plasma Membrane But Abolished by Its Targeting to Nucleus

(2009) H. Ie Kim et al.   JOURNAL OF BIOCHEMISTRY

Role for EPS8 in squamous carcinogenesis

(2008) Huixin Wang et al.   CARCINOGENESIS

Epidermal Growth Factor Receptor Pathway Substrate 8 Is Overexpressed in Human Pituitary Tumors: Role in Proliferation and Survival

(2008) Mei Xu et al.   ENDOCRINOLOGY

Brk is coamplified with ErbB2 to promote proliferation in breast cancer

(2008) B. Xiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA