SENP1/HIF-1α feedback loop modulates hypoxia-induced cell proliferation, invasion, and EMT in human osteosarcoma cells

SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop

(2017) Chun-Ping Cui et al.   GUT

Osteosarcoma: Cells-of-Origin, Cancer Stem Cells, and Targeted Therapies

(2016) Ander Abarrategi et al.   Stem Cells International

SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling

(2015) Jun Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SENP1 regulates cell migration and invasion in neuroblastoma

(2015) Yan Xiang-ming et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

The HIF-1α/CXCR4 pathway supports hypoxia-induced metastasis of human osteosarcoma cells

(2015) Guofeng Guan et al.   CANCER LETTERS

HIF-1 at the crossroads of hypoxia, inflammation, and cancer

(2015) Kuppusamy Balamurugan   INTERNATIONAL JOURNAL OF CANCER

Hypoxia-induced apoptosis is blocked by adrenomedullin via upregulation of Bcl-2 in human osteosarcoma cells

(2015) XUE-YUAN WU et al.   ONCOLOGY REPORTS

Inhibition of Hypoxia-inducible Factor-1 Alpha Radiosensitized MG-63 Human Osteosarcoma Cells in Vitro

(2015) Zhu Jin et al.   TUMORI

Inhibition of Hypoxia-inducible Factor-1 Alpha Radiosensitized MG-63 Human Osteosarcoma Cells in Vitro

(2015) Zhu Jin et al.   TUMORI JOURNAL

SENP1 desensitizes hypoxic ovarian cancer cells to cisplatin by up-regulating HIF-1α

(2015) Qilin Ao et al.   Scientific Reports

Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma

(2014) Mingjun Guo et al.   PLoS One

Gli-1 is crucial for hypoxia-induced epithelial-mesenchymal transition and invasion of breast cancer

(2014) Jianjun Lei et al.   TUMOR BIOLOGY

Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology

(2013) Gregg L. Semenza   Annual Review of Pathology-Mechanisms of Disease

Hypoxia and lymphangiogenesis in tumor microenvironment and metastasis

(2013) Rui-Cheng Ji   CANCER LETTERS

Inhibition of SENP1 induces radiosensitization in lung cancer cells

(2013) RUO-TIAN WANG et al.   Experimental and Therapeutic Medicine

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Expression and stability of hypoxia inducible factor 1α in osteosarcoma

(2012) Amal El Naggar et al.   PEDIATRIC BLOOD & CANCER

Hypoxia, stem cells and bone tumor

(2011) Wen Zeng et al.   CANCER LETTERS

Induction of SENP1 in Endothelial Cells Contributes to Hypoxia-driven VEGF Expression and Angiogenesis

(2010) Ying Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

(2010) Douglas S. Micalizzi et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

Roles of p53, Myc and HIF-1 in Regulating Glycolysis — the Seventh Hallmark of Cancer

(2008) S. J. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES