Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen-mediated changes in cell cycle regulatory circuits

Suppression of Spry1 inhibits triple-negative breast cancer malignancy by decreasing EGF/EGFR mediated mesenchymal phenotype

(2016) Qing He et al.   Scientific Reports

Molecular mechanisms underlying RB protein function

(2013) Frederick A. Dick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Spry1 and Spry4 Differentially Regulate Human Aortic Smooth Muscle Cell Phenotype via Akt/FoxO/Myocardin Signaling

(2013) Xuehui Yang et al.   PLoS One

SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis

(2012) Meiling Gao et al.   EMBO Molecular Medicine

Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cells

(2012) T Shimura et al.   Oncogenesis

Spry1 Is Expressed in Hemangioblasts and Negatively Regulates Primitive Hematopoiesis and Endothelial Cell Function

(2011) Xuehui Yang et al.   PLoS One

Silencing of SPRY1 Triggers Complete Regression of Rhabdomyosarcoma Tumors Carrying a Mutated RAS Gene

(2010) G. Schaaf et al.   CANCER RESEARCH

ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence

(2009) Sebastien Cagnol et al.   FEBS Journal

Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia

(2008) Xuehui Yang et al.   DEVELOPMENTAL BIOLOGY

Akt Regulates the Survival of Vascular Smooth Muscle Cells via Inhibition of FoxO3a and GSK3

(2008) David Allard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE