Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cells

Targeting the AKT/GSK3β/Cyclin D1/Cdk4 Survival Signaling Pathway for Eradication of Tumor Radioresistance Acquired by Fractionated Radiotherapy

(2011) Tsutomu Shimura et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Selection of radioresistant tumor cells and presence of ALDH1 activity in vitro

(2011) Julia Mihatsch et al.   RADIOTHERAPY AND ONCOLOGY

Cancer Stem Cell Radioresistance and Enrichment: Where Frontline Radiation Therapy May Fail in Lung and Esophageal Cancers

(2011) Giang Huong Nguyen et al.   Cancers

Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3

(2010) Li Ma et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells

(2010) S.-M. Che et al.   DISEASES OF THE ESOPHAGUS

Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3β-mediated cyclin D1 overexpression

(2010) T Shimura et al.   ONCOGENE

PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells

(2009) Anne-Marie Bleau et al.   Cell Stem Cell

CD133 as a Marker for Cancer Stem Cells: Progresses and Concerns

(2009) Yaojiong Wu et al.   STEM CELLS AND DEVELOPMENT

Targeting Stem Cells-Clinical Implications for Cancer Therapy

(2009) Lan Tu et al.   Current Stem Cell Research & Therapy

Regulation of Mammary Stem/Progenitor Cells by PTEN/Akt/β-Catenin Signaling

(2009) Hasan Korkaya et al.   PLOS BIOLOGY

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

(2008) D. Hambardzumyan et al.   GENES & DEVELOPMENT

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

(2008) A. Dubrovska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition

(2008) Christine E. Eyler et al.   STEM CELLS

Bloom's Syndrome Helicase and Mus81 are Required to Induce Transient Double-strand DNA Breaks in Response to DNA Replication Stress

(2007) Tsutomu Shimura et al.   JOURNAL OF MOLECULAR BIOLOGY