Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2
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Title
Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2
Authors
Keywords
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Journal
JOURNAL OF CELL SCIENCE
Volume 130, Issue 21, Pages 3676-3684
Publisher
The Company of Biologists
Online
2017-09-08
DOI
10.1242/jcs.203703
References
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Related references
Note: Only part of the references are listed.- Microtubule minus-end regulation at spindle poles by an ASPM–katanin complex
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- ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules
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- Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate
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- A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer
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- Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
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- NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures
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- An Asp–CaM complex is required for centrosome–pole cohesion and centrosome inheritance in neural stem cells
- (2015) Todd Schoborg et al. JOURNAL OF CELL BIOLOGY
- Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle
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- Reversible centriole depletion with an inhibitor of Polo-like kinase 4
- (2015) Y. L. Wong et al. SCIENCE
- Dissecting the Function and Assembly of Acentriolar Microtubule Organizing Centers in Drosophila Cells In Vivo
- (2015) Janina Baumbach et al. PLoS Genetics
- Cortical neurogenesis in the absence of centrioles
- (2014) Ryan Insolera et al. NATURE NEUROSCIENCE
- Disruption of Aspm causes microcephaly with abnormal neuronal differentiation
- (2013) Akira Fujimori et al. BRAIN & DEVELOPMENT
- Analysis ofASPMin an ethnically diverse cohort of 400 patient samples: perspectives of the molecular diagnostic laboratory
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- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Cdk5rap2 exposes the centrosomal root of microcephaly syndromes
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- Human ASPM participates in spindle organisation, spindle orientation and cytokinesis
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- CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response
- (2010) Alexis R. Barr et al. JOURNAL OF CELL BIOLOGY
- CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex
- (2010) Yuk-Kwan Choi et al. JOURNAL OF CELL BIOLOGY
- Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
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- (2009) Alain D. Silk et al. JOURNAL OF CELL BIOLOGY
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- (2009) Kohei Nishimura et al. NATURE METHODS
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- CDK5RAP2 Is a Pericentriolar Protein That Functions in Centrosomal Attachment of the γ-Tubulin Ring Complex
- (2007) Ka-Wing Fong et al. MOLECULAR BIOLOGY OF THE CELL
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