Labile ruthenium(ii) complexes with extended phenyl-substituted terpyridyl ligands: synthesis, aquation and anticancer evaluation

Group 9 Organometallic Compounds for Therapeutic and Bioanalytical Applications

(2014) Dik-Lung Ma et al.   ACCOUNTS OF CHEMICAL RESEARCH

Comparison Between Polypyridyl and Cyclometalated Ruthenium(II) Complexes: Anticancer Activities Against 2D and 3D Cancer Models

(2014) Huaiyi Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

[Ir(N^N^N)(C^N)L]+: A New Family of Luminophores Combining Tunability and Enhanced Photostability

(2014) Danielle N. Chirdon et al.   INORGANIC CHEMISTRY

Targeting Nucleus DNA with a Cyclometalated Dipyridophenazineruthenium(II) Complex

(2014) Huaiyi Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The path for metal complexes to a DNA target

(2013) Alexis C. Komor et al.   CHEMICAL COMMUNICATIONS

The Cell’s Nucleolus: an Emerging Target for Chemotherapeutic Intervention

(2013) Amanda J. Pickard et al.   ChemMedChem

Bioactive iridium and rhodium complexes as therapeutic agents

(2013) Chung-Hang Leung et al.   COORDINATION CHEMISTRY REVIEWS

Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα

(2013) Pingyu Zhang et al.   DALTON TRANSACTIONS

Dual topoisomerase I and II poisoning by chiral Ru(II) complexes containing 2-thiophenylimidazo[4,5-f][1,10]phenanthroline derivatives

(2013) Yu-Chuan Wang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The induction of mitochondria-mediated apoptosis in cancer cells by ruthenium(ii) asymmetric complexes

(2013) Chen Qian et al.   Metallomics

The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition

(2013) Brenda L. Bloodgood et al.   NATURE

Single-chromosome transcriptional profiling reveals chromosomal gene expression regulation

(2013) Marshall J Levesque et al.   NATURE METHODS

Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets

(2013) Hyeun Joong Yoon et al.   Nature Nanotechnology

A Metal-Based Inhibitor of Tumor Necrosis Factor-α

(2012) Chung-Hang Leung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity

(2012) Vania Vidimar et al.   BIOCHEMICAL PHARMACOLOGY

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Targeting and delivery of platinum-based anticancer drugs

(2012) Xiaoyong Wang et al.   CHEMICAL SOCIETY REVIEWS

Strained Ruthenium Complexes Are Potent Light-Activated Anticancer Agents

(2012) Brock S. Howerton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Osmium(vi) nitrido complexes bearing azole heterocycles: a new class of antitumor agents

(2012) Wen-Xiu Ni et al.   Chemical Science

Anticancer Metallotherapeutics in Preclinical Development

(2011) G. N. Kaluderovic et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis, DNA-binding and topoisomerase inhibitory activity of ruthenium(II) polypyridyl complexes

(2011) Ke-Jie Du et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Half-Sandwich Iridium Anticancer Complexes

(2011) Zhe Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Morphological and cytoskeletal changes of pancreatic cancer cells in three-dimensional spheroidal culture

(2011) Yoko Matsuda et al.   Medical Molecular Morphology

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

An anti-cancer trinuclear ruthenium(iii) complex with 2-thiosalicylate ligands attenuates Wnt-β-catenin signaling

(2011) Sharon Lai-Fung Chan et al.   Chemical Science

Droplet-based microfluidic system for multicellular tumor spheroid formation and anticancer drug testing

(2010) Linfen Yu et al.   LAB ON A CHIP

In Vitro Transcription Inhibition by Ruthenium(II) Polypyridyl Complexes with Electropositive Ancillary Ligands

(2009) Feng Gao et al.   INORGANIC CHEMISTRY

Cytotoxicity, Hydrophobicity, Uptake, and Distribution of Osmium(II) Anticancer Complexes in Ovarian Cancer Cells

(2009) Sabine H. van Rijt et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

Identification of Gastric Cancer Stem Cells Using the Cell Surface Marker CD44

(2009) Shigeo Takaishi et al.   STEM CELLS

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

Modelling tissues in 3D: the next future of pharmaco-toxicology and food research?

(2008) Giovanna Mazzoleni et al.   Genes and Nutrition

3-D Tumor Model forIn VitroEvaluation of Anticancer Drugs

(2008) Jayme L. Horning et al.   MOLECULAR PHARMACEUTICS

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA