A novel interplay between HOTAIR and DNA methylation in osteosarcoma cells indicates a new therapeutic strategy

Long noncoding RNA HOTAIR promotes metastasis of renal cell carcinoma by up-regulating histone H3K27 demethylase JMJD3

(2017) Ming Xia et al.   Oncotarget

The HOTAIR, PRNCR1 and POLR2E polymorphisms are associated with cancer risk: a meta-analysis

(2017) Haiyan Chu et al.   Oncotarget

Long Non-Coding RNA HOTAIR Regulates the Proliferation, Self-Renewal Capacity, Tumor Formation and Migration of the Cancer Stem-Like Cell (CSC) Subpopulation Enriched from Breast Cancer Cells

(2017) Jia Deng et al.   PLoS One

The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition

(2016) C Battistelli et al.   ONCOGENE

Role of HOTAIR in the diagnosis and prognosis of acute leukemia

(2016) Yuan-Yuan Zhang et al.   ONCOLOGY REPORTS

LncRNA HOTAIR promotes cisplatin resistance in gastric cancer by targeting miR-126 to activate the PI3K/AKT/MRP1 genes

(2016) Jin Yan et al.   TUMOR BIOLOGY

Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma

(2015) YANSHENG WU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Long noncoding RNA-HOTAIR affects chemoresistance by regulating HOXA1 methylation in small cell lung cancer cells

(2015) Shun Fang et al.   LABORATORY INVESTIGATION

The role of circulating miRNAs in multiple myeloma

(2015) Ji Zhang et al.   Science China-Life Sciences

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

(2015) Wei-Cheng Liang et al.   Oncotarget

HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer

(2015) Andrew E. Teschendorff et al.   Genome Medicine

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.

(2015) Sevin Turcan et al.   Oncotarget

Inactivation of the CDKN2A Tumor-Suppressor Gene by Deletion or Methylation Is Common at Diagnosis in Follicular Lymphoma and Associated with Poor Clinical Outcome

(2014) A. Alhejaily et al.   CLINICAL CANCER RESEARCH

DNMT1-MicroRNA126 Epigenetic Circuit Contributes to Esophageal Squamous Cell Carcinoma Growth via ADAM9-EGFR-AKT Signaling

(2014) R. Liu et al.   CLINICAL CANCER RESEARCH

Enhancement of radiosensitivity by 5-Aza-CdR through activation of G2/M checkpoint response and apoptosis in osteosarcoma cells

(2014) Yi Li et al.   TUMOR BIOLOGY

DNA Methylation and Cancer Development: Molecular Mechanism

(2013) Haleh Akhavan-Niaki et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Knockdown of Long Non-coding RNA HOTAIR Suppresses Tumor Invasion and Reverses Epithelial-mesenchymal Transition in Gastric Cancer

(2013) Zhi-Yuan Xu et al.   International Journal of Biological Sciences

KRASmutations andCDKN2Apromoter methylation show an interactive adverse effect on survival and predict recurrence of rectal cancer

(2013) Maija R. J. Kohonen-Corish et al.   INTERNATIONAL JOURNAL OF CANCER

The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs

(2013) Amanda N. Kallen et al.   MOLECULAR CELL

GFOLD: a generalized fold change for ranking differentially expressed genes from RNA-seq data

(2012) Jianxing Feng et al.   BIOINFORMATICS

Perifosine Induces Cell Apoptosis in Human Osteosarcoma Cells: New Implication for Osteosarcoma Therapy?

(2012) Chen Yao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia

(2012) Emmanuel J. Volanakis et al.   EXPERIMENTAL HEMATOLOGY

HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer

(2012) K Kim et al.   ONCOGENE

Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

(2011) Zhe Yang et al.   ANNALS OF SURGICAL ONCOLOGY

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

(2011) C Braconi et al.   ONCOGENE

Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

(2011) Jiang Lin et al.   PLoS One

MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1

(2010) Sha Zhao et al.   ARTHRITIS AND RHEUMATISM

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

(2010) Diego Pasini et al.   NATURE

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

DNMT3AMutations in Acute Myeloid Leukemia

(2010) Timothy J. Ley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel therapeutic strategy for osteosarcoma targeting osteoclast differentiation, bone-resorbing activity, and apoptosis pathway

(2008) T. Akiyama et al.   MOLECULAR CANCER THERAPEUTICS