Untranslated regions of mRNA and their role in regulation of gene expression in protozoan parasites

Transcriptomic profiling of gene expression and RNA processing duringLeishmania majordifferentiation

(2015) Laura A. L. Dillon et al.   NUCLEIC ACIDS RESEARCH

The eIF3 complex ofLeishmania—subunit composition and mode of recruitment to different cap-binding complexes

(2015) Shimi Meleppattu et al.   NUCLEIC ACIDS RESEARCH

Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel Transcript Features

(2015) Abhinay Ramaprasad et al.   PLoS One

Strand-specific RNA-Seq reveals widespread and developmentally regulated transcription of natural antisense transcripts in Plasmodium falciparum

(2014) T Siegel et al.   BMC GENOMICS

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma brucei

(2014) Bryan C Jensen et al.   BMC GENOMICS

The emerging role of RNA-binding proteins in the life cycle ofTrypanosoma brucei

(2014) Nikolay G. Kolev et al.   CELLULAR MICROBIOLOGY

Diagnosis of Trypanosomatid Infections

(2014) Pablo González-Andrade et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

SLaP mapper: A webserver for identifying and quantifying spliced-leader addition and polyadenylation site usage in kinetoplastid genomes

(2014) Michael Fiebig et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A short RNA stem-loop is necessary and sufficient for repression of gene expression during early logarithmic phase in trypanosomes

(2014) S. M. Fernandez-Moya et al.   NUCLEIC ACIDS RESEARCH

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages

(2014) Juan-José Vasquez et al.   NUCLEIC ACIDS RESEARCH

Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

(2014) Aditi Singh et al.   NUCLEIC ACIDS RESEARCH

Two splicing factors carrying serine-arginine motifs, TSR1 and TSR1IP, regulate splicing, mRNA stability, and rRNA processing inTrypanosoma brucei

(2014) Sachin Kumar Gupta et al.   RNA Biology

Deciphering RNA regulatory elements in trypanosomatids: one piece at a time or genome-wide?

(2014) Vahid H. Gazestani et al.   TRENDS IN PARASITOLOGY

Genome-wide regulatory dynamics of translation in the Plasmodium falciparum asexual blood stages

(2014) Florence Caro et al.   eLife

Evidence for a negative feedback control mediated by the 3′ untranslated region assuring the low expression level of the RNA binding protein TcRBP19 in T. cruzi epimastigotes

(2013) Leticia Pérez-Díaz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-seq

(2013) Alberto Rastrojo et al.   BMC GENOMICS

The Unfolded Protein Response in the Protozoan Parasite Toxoplasma gondii Features Translational and Transcriptional Control

(2013) Bradley R. Joyce et al.   EUKARYOTIC CELL

A short bifunctional element operates to positively or negatively regulate ESAG9 expression in different developmental forms of Trypanosoma brucei

(2013) S. L. Monk et al.   JOURNAL OF CELL SCIENCE

Adenosine–uridine-rich element is one of the required cis-elements for epimastigote form stage-specific gene expression of the congolense epimastigote specific protein

(2013) Keisuke Suganuma et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Insights into the regulation of GPEET procyclin during differentiation from early to late procyclic forms of Trypanosoma brucei

(2013) Sebastian Knüsel et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

A molecular switch in the efficiency of translation reinitiation controls expression ofvar2csa, a gene implicated in pregnancy-associated malaria

(2013) Cristina Bancells et al.   MOLECULAR MICROBIOLOGY

The hnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life cycle stages of the parasite and regulates splicing and mRNA stability

(2013) Sachin Kumar Gupta et al.   NUCLEIC ACIDS RESEARCH

Nutritional stress affects an atypical cap-binding protein in Leishmania

(2013) Alexandra Zinoviev et al.   RNA Biology

Post-Transcriptional Regulation of the Trypanosome Heat Shock Response by a Zinc Finger Protein

(2013) Dorothea Droll et al.   PLoS Pathogens

Polysome profiling reveals translational control of gene expression in the human malaria parasite Plasmodium falciparum

(2013) Evelien M Bunnik et al.   GENOME BIOLOGY

Genome-wide analysis of 3′-untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes

(2013) Javier G. De Gaudenzi et al.   PeerJ

Translocation of Sickle Cell Erythrocyte MicroRNAs into Plasmodium falciparum Inhibits Parasite Translation and Contributes to Malaria Resistance

(2012) Gregory LaMonte et al.   Cell Host & Microbe

A Plasmodium Calcium-Dependent Protein Kinase Controls Zygote Development and Transmission by Translationally Activating Repressed mRNAs

(2012) Sarah Sebastian et al.   Cell Host & Microbe

Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements

(2012) Lucy W. Barrett et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Diversity of Eukaryotic Translational Initiation Factor eIF4E in Protists

(2012) Rosemary Jagus et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Evolutionary Conservation and Diversification of the Translation Initiation Apparatus in Trypanosomatids

(2012) Alexandra Zinoviev et al.   COMPARATIVE AND FUNCTIONAL GENOMICS

Functional Analysis of Sequence Motifs Involved in the Polyadenylation of Trichomonas vaginalis mRNAs

(2012) Vanessa Fuentes et al.   EUKARYOTIC CELL

A 43-Nucleotide U-rich Element in 3′-Untranslated Region of Large Number ofTrypanosoma cruziTranscripts Is Important for mRNA Abundance in Intracellular Amastigotes

(2012) Zhu-Hong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Toxoplasma gondii 5′ UTR with Encyclopedic TSS Information

(2012) J. Yamagishi et al.   JOURNAL OF PARASITOLOGY

Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica

(2012) Chung-Chau Hon et al.   NUCLEIC ACIDS RESEARCH

Identification of the regulatory elements controlling the transmission stage-specific gene expression of PAD1 in Trypanosoma brucei

(2012) Paula MacGregor et al.   NUCLEIC ACIDS RESEARCH

Sequence analysis of the 3’-untranslated region of HSP70 (type I) genes in the genus Leishmania: its usefulness as a molecular marker for species identification

(2012) Jose M Requena et al.   Parasites & Vectors

mRNA Decay Proteins Are Targeted to poly(A)+ RNA and dsRNA-Containing Cytoplasmic Foci That Resemble P-Bodies in Entamoeba histolytica

(2012) Itzel López-Rosas et al.   PLoS One

Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation

(2011) Conan Chow et al.   CELLULAR MICROBIOLOGY

Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome

(2011) Shulamit Michaeli   Future Microbiology

The post-transcriptional trans-acting regulator, TbZFP3, co-ordinates transmission-stage enriched mRNAs in Trypanosoma brucei

(2011) Pegine B. Walrad et al.   NUCLEIC ACIDS RESEARCH

A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways

(2011) Alexandra Zinoviev et al.   NUCLEIC ACIDS RESEARCH

Dual targeting of isoleucyl-tRNA synthetase in Trypanosoma brucei is mediated through alternative trans-splicing

(2011) Jochen Rettig et al.   NUCLEIC ACIDS RESEARCH

Identification of the HSP70-II gene in Leishmania braziliensis HSP70 locus: genomic organization and UTRs characterization

(2011) César A Ramírez et al.   Parasites & Vectors

The composition of upstream open reading frames (uORF) in four genes from Trypanosoma cruzi typical strains

(2011) Lauren Hubert Jaeger et al.   PARASITOLOGY RESEARCH

Is There a Classical Nonsense-Mediated Decay Pathway in Trypanosomes?

(2011) Praveen Delhi et al.   PLoS One

Two covariance models for iron-responsive elements

(2011) Stewart G Stevens et al.   RNA Biology

Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania

(2010) T. Lahav et al.   FASEB JOURNAL

MicroRNAs of parasites: current status and future perspectives

(2010) Quan Liu et al.   PARASITOLOGY RESEARCH

A Metazoan/Plant-like Capping Enzyme and Cap Modified Nucleotides in the Unicellular Eukaryote Trichomonas vaginalis

(2010) Augusto Simoes-Barbosa et al.   PLoS Pathogens

Serum-Dependent Selective Expression of EhTMKB1-9, a Member of Entamoeba histolytica B1 Family of Transmembrane Kinases

(2010) Shiteshu Shrimal et al.   PLoS Pathogens

Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei

(2010) Daniel Nilsson et al.   PLoS Pathogens

Role of 5′- and 3′-untranslated regions of mRNAs in human diseases

(2009) Sangeeta Chatterjee et al.   BIOLOGY OF THE CELL

Key role of the 3' untranslated region in the cell cycle regulated expression of the Leishmania infantum histone H2A genes: minor synergistic effect of the 5' untranslated region

(2009) Daniel R Abanades et al.   BMC MOLECULAR BIOLOGY

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Identification of microRNA in the protist Trichomonas vaginalis

(2009) Wei-Chen Lin et al.   GENOMICS

Responsiveness of Trichomonas vaginalis to iron concentrations: Evidence for a post-transcriptional iron regulation by an IRE/IRP-like system

(2009) J.C. Torres-Romero et al.   INFECTION GENETICS AND EVOLUTION

PfeIK1, a eukaryotic initiation factor 2α kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation

(2009) Clare Fennell et al.   MALARIA JOURNAL

Hypermethylated cap 4 maximizesTrypanosoma bruceitranslation

(2009) Jesse R. Zamudio et al.   MOLECULAR MICROBIOLOGY

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions

(2009) Yael Yoffe et al.   NUCLEIC ACIDS RESEARCH

The composition of untranslated regions in Trypanosoma cruzi genes

(2009) Adeilton Brandão et al.   PARASITOLOGY INTERNATIONAL

Giardiavirus Internal Ribosome Entry Site Has an Apparently Unique Mechanism of Initiating Translation

(2009) Srinivas Garlapati et al.   PLoS One

Preferential translation of Hsp83 in Leishmania requires a thermosensitive polypyrimidine-rich element in the 3' UTR and involves scanning of the 5' UTR

(2009) M. David et al.   RNA

Differential Trypanosome Surface Coat Regulation by a CCCH Protein That Co-Associates with procyclin mRNA cis-Elements

(2009) Pegine Walrad et al.   PLoS Pathogens

An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria

(2009) Borko Amulic et al.   PLoS Pathogens

MicroRNA switches in Trypanosoma brucei

(2008) Bibekanand Mallick et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In silico analysis of EST and genomic sequences allowed the prediction of cis-regulatory elements for Entamoeba histolytica mRNA polyadenylation

(2008) Absalom Zamorano et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2  phosphorylation at Thr169

(2008) S. Kramer et al.   JOURNAL OF CELL SCIENCE

snoRNA, a Novel Precursor of microRNA in Giardia lamblia

(2008) Ashesh A. Saraiya et al.   PLoS Pathogens

A Genetically Hard-Wired Metabolic Transcriptome in Plasmodium falciparum Fails to Mount Protective Responses to Lethal Antifolates

(2008) Karthikeyan Ganesan et al.   PLoS Pathogens

Regulation of an amino acid transporter mRNA in Trypanosoma brucei

(2007) Ana Robles et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Coordinate regulation of a family of promastigote-enriched mRNAs by the 3′UTR PRE element in Leishmania mexicana

(2007) Timothy R. Holzer et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY