Evolutionary Conservation and Diversification of the Translation Initiation Apparatus in Trypanosomatids

Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection

(2011) Maritza Jaramillo et al.   Cell Host & Microbe

Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome

(2011) Shulamit Michaeli   Future Microbiology

A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways

(2011) Alexandra Zinoviev et al.   NUCLEIC ACIDS RESEARCH

Functional Characterization of Three Leishmania Poly(A) Binding Protein Homologues with Distinct Binding Properties to RNA and Protein Partners

(2010) Tamara D. da Costa Lima et al.   EUKARYOTIC CELL

Multiple levels of gene regulation mediate differentiation of the intracellular pathogen Leishmania

(2010) T. Lahav et al.   FASEB JOURNAL

The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties

(2010) Eden R. Freire et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The 5′-7-Methylguanosine Cap on Eukaryotic mRNAs Serves Both to Stimulate Canonical Translation Initiation and to Block an Alternative Pathway

(2010) Sarah F. Mitchell et al.   MOLECULAR CELL

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Hypermethylated cap 4 maximizesTrypanosoma bruceitranslation

(2009) Jesse R. Zamudio et al.   MOLECULAR MICROBIOLOGY

Differential contribution of the m7G-cap to the 5′ end-dependent translation initiation of mammalian mRNAs

(2009) Dmitri E. Andreev et al.   NUCLEIC ACIDS RESEARCH

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E–eIF4G interactions

(2009) Yael Yoffe et al.   NUCLEIC ACIDS RESEARCH

Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins

(2009) L. Madeira da Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preferential translation of Hsp83 in Leishmania requires a thermosensitive polypyrimidine-rich element in the 3' UTR and involves scanning of the 5' UTR

(2009) M. David et al.   RNA

Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2

(2009) Morris E Feldman et al.   PLOS BIOLOGY

Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2  phosphorylation at Thr169

(2008) S. Kramer et al.   JOURNAL OF CELL SCIENCE

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation

(2008) Valentina Gandin et al.   NATURE

Translation factors promote the formation of two states of the closed-loop mRNP

(2008) Nadia Amrani et al.   NATURE

Retooling Leishmania metabolism: from sand fly gut to human macrophage

(2007) Doron Rosenzweig et al.   FASEB JOURNAL