Oxygen activation by mononuclear nonheme iron dioxygenases involved in the degradation of aromatics

Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants

(2017) Subhasree Kal et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Oxidation of alkane and alkene moieties with biologically inspired nonheme iron catalysts and hydrogen peroxide: from free radicals to stereoselective transformations

(2017) Giorgio Olivo et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Engineering a Chemical Switch into the Light-driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification

(2016) Daniel Harder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Spectroscopic analyses of 2-oxoglutarate-dependent oxygenases: TauD as a case study

(2016) Denis A. Proshlyakov et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

A short history of heme dioxygenases: rise, fall and rise again

(2016) Emma L. Raven   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

A chemical biology route to site-specific authentic protein modifications

(2016) A. Yang et al.   SCIENCE

The “Gln-Type” Thiol Dioxygenase from Azotobacter vinelandii Is a 3-Mercaptopropionic Acid Dioxygenase

(2015) Brad S. Pierce et al.   BIOCHEMISTRY

Rate-Determining Attack on Substrate Precedes Rieske Cluster Oxidation during Cis-Dihydroxylation by Benzoate Dioxygenase

(2015) Brent S. Rivard et al.   BIOCHEMISTRY

The Cysteine Dioxygenase Homologue fromPseudomonas aeruginosaIs a 3-Mercaptopropionate Dioxygenase

(2015) Egor P. Tchesnokov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Iron Reservoir to the Catalytic Metal

(2015) Fange Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase

(2014) Cory J. Knoot et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme-dependent dioxygenases in tryptophan oxidation

(2013) Jiafeng Geng et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mechanistic Implications of Persulfenate and Persulfide Binding in the Active Site of Cysteine Dioxygenase

(2013) Richard J. Souness et al.   BIOCHEMISTRY

Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH

(2013) Camden M. Driggers et al.   JOURNAL OF MOLECULAR BIOLOGY

Rate-Determining Water-Assisted O–O Bond Cleavage of an FeIII-OOH Intermediate in a Bio-inspired Nonheme Iron-Catalyzed Oxidation

(2013) Williamson N. Oloo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visualizing the substrate-, superoxo-, alkylperoxo-, and product-bound states at the nonheme Fe(II) site of homogentisate dioxygenase

(2013) J.-H. Jeoung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxygen activation by homoprotocatechuate 2,3-dioxygenase: a QM/MM study reveals the key intermediates in the activation cycle

(2013) Geng Dong et al.   Chemical Science

Ring-Cleaving Dioxygenases with a Cupin Fold

(2012) Susanne Fetzner   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Substrate-Mediated Oxygen Activation by Homoprotocatechuate 2,3-Dioxygenase: Intermediates Formed by a Tyrosine 257 Variant

(2012) Michael M. Mbughuni et al.   BIOCHEMISTRY

Structural Basis for the Role of Tyrosine 257 of Homoprotocatechuate 2,3-Dioxygenase in Substrate and Oxygen Activation

(2012) Elena G. Kovaleva et al.   BIOCHEMISTRY

EPR detection of Fe(V)=O active species in nonheme iron-catalyzed oxidations

(2012) Oleg Y. Lyakin et al.   CATALYSIS COMMUNICATIONS

The alkenyl migration mechanism catalyzed by extradiol dioxygenases: a hybrid DFT study

(2012) Tomasz Borowski et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Chemical Rescue of the Distal Histidine Mutants of Tryptophan 2,3-Dioxygenase

(2012) Jiafeng Geng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxygen activation in extradiol catecholate dioxygenases – a density functional study

(2012) Gemma J. Christian et al.   Chemical Science

The biology and chemistry of high-valent iron–oxo and iron–nitrido complexes

(2012) Johannes Hohenberger et al.   Nature Communications

Structural insight into the substrate- and dioxygen-binding manner in the catalytic cycle of rieske nonheme iron oxygenase system, carbazole 1,9a-dioxygenase

(2012) Yuji Ashikawa et al.   BMC STRUCTURAL BIOLOGY

Oxy Intermediates of Homoprotocatechuate 2,3-Dioxygenase: Facile Electron Transfer between Substrates

(2011) Michael M. Mbughuni et al.   BIOCHEMISTRY

Enzyme Reactivation by Hydrogen Peroxide in Heme-based Tryptophan Dioxygenase

(2011) Rong Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Theoretical Study on the Mechanism of the Oxygen Activation Process in Cysteine Dioxygenase Enzymes

(2011) Devesh Kumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Observation of Fe(V)=O using variable-temperature mass spectrometry and its enzyme-like C–H and C=C oxidation reactions

(2011) Irene Prat et al.   Nature Chemistry

Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme

(2010) M. M. Mbughuni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial degradation of lignin: how a bulky recalcitrant polymer is efficiently recycled in nature and how we can take advantage of this

(2009) Francisco J. Ruiz-Dueñas et al.   Microbial Biotechnology

Bacterial Degradation of Aromatic Compounds

(2009) Jong-Su Seo et al.   International Journal of Environmental Research and Public Health

A Putative Fe2+-Bound Persulfenate Intermediate in Cysteine Dioxygenase†‡

(2008) Chad R. Simmons et al.   BIOCHEMISTRY

Intermediate in the O−O Bond Cleavage Reaction of an Extradiol Dioxygenase†,‡

(2008) Elena G. Kovaleva et al.   BIOCHEMISTRY

Non-heme iron-dependent dioxygenases: unravelling catalytic mechanisms for complex enzymatic oxidations

(2008) Timothy DH Bugg et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Mechanism of extradiol aromatic ring-cleaving dioxygenases

(2008) John D Lipscomb   CURRENT OPINION IN STRUCTURAL BIOLOGY

From Oxygenase to Sleep

(2008) Osamu Hayaishi   JOURNAL OF BIOLOGICAL CHEMISTRY

3-Mercaptopropionate Dioxygenase, a Cysteine Dioxygenase Homologue, Catalyzes the Initial Step of 3-Mercaptopropionate Catabolism in the 3,3-Thiodipropionic Acid-degrading BacteriumVariovorax paradoxus

(2008) Nadine Bruland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence from Mechanistic Probes for Distinct Hydroperoxide Rearrangement Mechanisms in the Intradiol and Extradiol Catechol Dioxygenases

(2008) Meite Xin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near-IR MCD of the Nonheme Ferrous Active Site in Naphthalene 1,2-Dioxygenase:  Correlation to Crystallography and Structural Insight into the Mechanism of Rieske Dioxygenases

(2008) Takehiro Ohta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY