MicroRNA-145 ModulatesN6-Methyladenosine Levels by Targeting the 3′-Untranslated mRNA Region of theN6-Methyladenosine Binding YTH Domain Family 2 Protein

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

Overexpression of miR-145–5p Inhibits Proliferation of Prostate Cancer Cells and Reduces SOX2 Expression

(2015) Mustafa Ozen et al.   CANCER INVESTIGATION

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

MicroRNA-145 and MicroRNA-133a Inhibited Proliferation, Migration, and Invasion, While Promoted Apoptosis in Hepatocellular Carcinoma Cells Via Targeting FSCN1

(2015) Guohui Wang et al.   DIGESTIVE DISEASES AND SCIENCES

FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice

(2015) Jingqing Chen et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Poly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer

(2015) Tanya Todorova et al.   TRENDS IN MOLECULAR MEDICINE

MiR-145 suppresses cell proliferation and motility by inhibiting ROCK1 in hepatocellular carcinoma

(2015) Wei Ding et al.   TUMOR BIOLOGY

EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma

(2015) Haiou Liu et al.   Nature Communications

miR-145 inhibits tumor growth and metastasis by targeting metadherin in high-grade serous ovarian carcinoma

(2015) Ruifen Dong et al.   Oncotarget

The Pivotal Regulatory Landscape of RNA Modifications

(2014) Sheng Li et al.   Annual Review of Genomics and Human Genetics

MicroRNA-145 suppresses hepatocellular carcinoma by targeting IRS1 and its downstream Akt signaling

(2014) Yelin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of the N6-methyladenosine RNA mark in gene regulation and its implications on development and disease

(2014) U. Chandola et al.   Briefings in Functional Genomics

FTO: linking m6A demethylation to adipogenesis

(2014) Moshe Shay Ben-Haim et al.   CELL RESEARCH

FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis

(2014) Xu Zhao et al.   CELL RESEARCH

Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase

(2014) Xiao-Li Ping et al.   CELL RESEARCH

miR-145 functions as tumor suppressor and targets two oncogenes, ANGPT2 and NEDD9, in renal cell carcinoma

(2014) Ruijing Lu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

lincRNA-RoR and miR-145 Regulate Invasion in Triple-Negative Breast Cancer via Targeting ARF6

(2014) Gabriel Eades et al.   MOLECULAR CANCER RESEARCH

MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

(2013) Huijuan Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells

(2013) Xiaona You et al.   CARCINOGENESIS

m6A mRNA Methylation: A New Circadian Pacesetter

(2013) Michael H. Hastings   CELL

Hepatitis B virus X protein protects hepatoma and hepatic cells from complement-dependent cytotoxicity by up-regulation of CD46

(2013) Shuai Zhang et al.   FEBS LETTERS

The Nuclear Import of Oncoprotein Hepatitis B X-interacting Protein Depends on Interacting with c-Fos and Phosphorylation of Both Proteins in Breast Cancer Cells

(2013) Yingyi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of miR-145 in cardiac myofibroblast differentiation

(2013) Yao-Sheng Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Role of miRNAs in Regulating Gene Expression Networks

(2013) Allan M. Gurtan et al.   JOURNAL OF MOLECULAR BIOLOGY

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

Novel RNA regulatory mechanisms revealed in the epitranscriptome

(2013) Yogesh Saletore et al.   RNA Biology

N6-methyl-adenosine modification in messenger and long non-coding RNA

(2013) Tao Pan   TRENDS IN BIOCHEMICAL SCIENCES

Mapping and significance of the mRNA methylome

(2013) Tennille Sibbritt et al.   Wiley Interdisciplinary Reviews-RNA

MiR-145 regulates PAK4 via the MAPK pathway and exhibits an antitumor effect in human colon cells

(2012) Zhigang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-145 modulates multiple components of the insulin-like growth factor pathway in hepatocellular carcinoma

(2012) Priscilla T.-Y. Law et al.   CARCINOGENESIS

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

A Role for miR-145 in Pulmonary Arterial Hypertension

(2012) Paola Caruso et al.   CIRCULATION RESEARCH

MicroRNA biogenesis: regulating the regulators

(2012) Emily F. Finnegan et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hepatitis B virus X protein modulates oncogene yes-associated protein by CREB to promote growth of hepatoma cells

(2012) Tao Zhang et al.   HEPATOLOGY

The Oncoprotein HBXIP Uses Two Pathways to Up-regulate S100A4 in Promotion of Growth and Migration of Breast Cancer Cells

(2012) Shuangping Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of miR-145 as a Key Regulator of the Pigmentary Process

(2012) Peter Dynoodt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

N6-methyl-adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function

(2012) Yamei Niu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Hepatitis B virus X protein activates CD59 involving DNA binding and let-7i in protection of hepatoma and hepatic cells from complement attack

(2011) Changliang Shan et al.   CARCINOGENESIS

Alternative miRNA Biogenesis Pathways and the Interpretation of Core miRNA Pathway Mutants

(2011) Jr-Shiuan Yang et al.   MOLECULAR CELL

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2

(2010) Changliang Shan et al.   CELL RESEARCH

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE