Heat shock proteins stimulate APOBEC-3–mediated cytidine deamination in the hepatitis B virus

Mechanisms of Hsp90 regulation

(2016) C. Prodromou   BIOCHEMICAL JOURNAL

Review: The HSP90 molecular chaperone-an enigmatic ATPase

(2016) Laurence H. Pearl   BIOPOLYMERS

The role of heat shock proteins in cancer

(2015) Georgios D. Lianos et al.   CANCER LETTERS

The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers

(2015) Brandon Leonard et al.   CANCER RESEARCH

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

(2015) Nidhi Sahni et al.   CELL

Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement

(2015) Sarah N. Fontaine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of the attenuated phenotype of human APOBEC3B DNA mutator enzyme

(2015) Vincent Caval et al.   NUCLEIC ACIDS RESEARCH

APOBEC3Bexpression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation

(2015) David W. Cescon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOBEC3 genes: retroviral restriction factors to cancer drivers

(2015) Stephen Henderson et al.   TRENDS IN MOLECULAR MEDICINE

APOBECs and virus restriction

(2015) Reuben S. Harris et al.   VIROLOGY

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

(2015) C. Swanton et al.   Cancer Discovery

Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

(2015) Artem G. Lada et al.   PLoS Genetics

Hsp90, the Concertmaster: Tuning Transcription

(2015) Nidhi Khurana et al.   Frontiers in Oncology

Human Papillomavirus E6 Triggers Upregulation of the Antiviral and Cancer Genomic DNA Deaminase APOBEC3B

(2014) Valdimara C. Vieira et al.   mBio

A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3′UTR enhances chromosomal DNA damage

(2014) Vincent Caval et al.   Nature Communications

Break-Induced Replication Is a Source of Mutation Clusters Underlying Kataegis

(2014) Cynthia J. Sakofsky et al.   Cell Reports

APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma

(2013) B. Leonard et al.   CANCER RESEARCH

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Evidence for APOBEC3B mutagenesis in multiple human cancers

(2013) Michael B Burns et al.   NATURE GENETICS

The Molecular Virology of Hepatitis B Virus

(2013) Corinna Bremer et al.   SEMINARS IN LIVER DISEASE

Genome-Wide Mutation Avalanches Induced in Diploid Yeast Cells by a Base Analog or an APOBEC Deaminase

(2013) Artem G. Lada et al.   PLoS Genetics

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

(2013) Benjamin JM Taylor et al.   eLife

Intrinsic immunity against retrotransposons by APOBEC cytidine deaminases

(2013) Atsushi Koito et al.   Frontiers in Microbiology

Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update

(2012) Daniel R. Ciocca et al.   ARCHIVES OF TOXICOLOGY

AID/APOBEC cytosine deaminase induces genome-wide kataegis

(2012) Artem G Lada et al.   Biology Direct

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Hypermutation of ApoB mRNA by Rat APOBEC-1 Overexpression Mimics APOBEC-3 Hypermutation

(2012) Zhigang Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells

(2012) Masanobu Shinohara et al.   Scientific Reports

Phosphorylation Directly Regulates the Intrinsic DNA Cytidine Deaminase Activity of Activation-induced Deaminase and APOBEC3G Protein

(2011) Zachary L. Demorest et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

(2011) J. F. Hultquist et al.   JOURNAL OF VIROLOGY

The Role of Amino-Terminal Sequences in Cellular Localization and Antiviral Activity of APOBEC3B

(2011) V. Pak et al.   JOURNAL OF VIROLOGY

Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90

(2010) Alexandre Orthwein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

APOBEC3G Contributes to HIV-1 Variation through Sublethal Mutagenesis

(2010) H. A. Sadler et al.   JOURNAL OF VIROLOGY

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

Hypermutation induced by APOBEC-1 overexpression can be eliminated

(2010) Z. Chen et al.   RNA

Robustness and Evolvability

(2010) Joanna Masel et al.   TRENDS IN GENETICS

Massive APOBEC3 Editing of Hepatitis B Viral DNA in Cirrhosis

(2010) Jean-Pierre Vartanian et al.   PLoS Pathogens

Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H

(2008) J. Kock et al.   JOURNAL OF GENERAL VIROLOGY