Genome-Wide Mutation Avalanches Induced in Diploid Yeast Cells by a Base Analog or an APOBEC Deaminase

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

(2013) Alex K. Shalek et al.   NATURE

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis

(2013) Benjamin JM Taylor et al.   eLife

AID/APOBEC cytosine deaminase induces genome-wide kataegis

(2012) Artem G Lada et al.   Biology Direct

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Dna polymerases and their role in genomic stability

(2012) Kristin A. Eckert et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools

(2012) Irina S.-R. Waisertreiger et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions

(2012) Steven A. Roberts et al.   MOLECULAR CELL

Pivotal Role of Inosine Triphosphate Pyrophosphatase in Maintaining Genome Stability and the Prevention of Apoptosis in Human Cells

(2012) Miriam Rose Menezes et al.   PLoS One

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent

(2012) Kin Chan et al.   PLoS Genetics

Quake: quality-aware detection and correction of sequencing errors

(2012) David R Kelley et al.   GENOME BIOLOGY

Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast

(2011) A. G. Lada et al.   BIOCHEMISTRY-MOSCOW

Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications

(2011) José Otero et al.   BMC GENOMICS

The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates

(2011) Uttiya Basu et al.   CELL

Analysis of a Single-stranded DNA-scanning Process in Which Activation-induced Deoxycytidine Deaminase (AID) Deaminates C to U Haphazardly and Inefficiently to Ensure Mutational Diversity

(2011) Phuong Pham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A continuum model for tumour suppression

(2011) Alice H. Berger et al.   NATURE

Replication Protein A (RPA) Hampers the Processive Action of APOBEC3G Cytosine Deaminase on Single-Stranded DNA

(2011) Artem G. Lada et al.   PLoS One

Epigenetic reprogramming: is deamination key to active DNA demethylation?

(2011) Marta Teperek-Tkacz et al.   REPRODUCTION

Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast

(2011) Alan J. Herr et al.   PLoS Genetics

Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break

(2010) Vladimir Poltoratsky et al.   MOLECULAR IMMUNOLOGY

Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint

(2010) Dinesh Kumar et al.   NUCLEIC ACIDS RESEARCH

Increased Mutagenesis and Unique Mutation Signature Associated with Mitotic Gene Conversion

(2010) W. M. Hicks et al.   SCIENCE

Evolution of the mutation rate

(2010) Michael Lynch   TRENDS IN GENETICS

The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis

(2010) K. T. Nishant et al.   PLoS Genetics

DNA polymerases at the eukaryotic fork—20 years later

(2009) Youri I. Pavlov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Human mutation rate associated with DNA replication timing

(2009) John A Stamatoyannopoulos et al.   NATURE GENETICS

A cancer-associated DNA polymerase   variant modeled in yeast causes a catastrophic increase in genomic instability

(2009) D. L. Daee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide view of the spectrum of spontaneous mutations in yeast

(2008) M. Lynch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA