Differential control of Toll-like receptor 4–induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases

Human regulatory B cells in health and disease: therapeutic potential

(2017) Claudia Mauri et al.   JOURNAL OF CLINICAL INVESTIGATION

B-1a Cells Protect Mice from Sepsis: Critical Role of CREB

(2017) Monowar Aziz et al.   JOURNAL OF IMMUNOLOGY

Role of Intrinsic Protein Disorder in the Function and Interactions of the Transcriptional Coactivators CREB-binding Protein (CBP) and p300

(2016) H. Jane Dyson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

(2016) Victoria A. McGuire et al.   Scientific Reports

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

Regulatory B10 cell development and function: Fig. 1.

(2015) Jacquelyn M. Lykken et al.   INTERNATIONAL IMMUNOLOGY

IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism

(2015) David E. Sanin et al.   JOURNAL OF IMMUNOLOGY

B10 Cells: A Functionally Defined Regulatory B Cell Subset

(2015) Thomas F. Tedder   JOURNAL OF IMMUNOLOGY

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

(2015) Rama Jain et al.   JOURNAL OF MEDICINAL CHEMISTRY

CREB phosphorylation at Ser133regulates transcription via distinct mechanisms downstream of cAMP and MAPK signalling

(2014) Shaista Naqvi et al.   BIOCHEMICAL JOURNAL

Transcriptional Regulation of IL-10 and Its Cell-Specific Role In Vivo

(2014) Kirsty F. MacKenzie et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Ca2+-related signaling events influence TLR9-induced IL-10 secretion in human B cells

(2014) Saskia Ziegler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The TLR and IL-1 signalling network at a glance

(2014) P. Cohen   JOURNAL OF CELL SCIENCE

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Novel Potent and Selective Inhibitors of p90 Ribosomal S6 Kinase Reveal the Heterogeneity of RSK Function in MAPK-Driven Cancers

(2014) Ida Aronchik et al.   MOLECULAR CANCER RESEARCH

IL-10 production by B cells is differentially regulated by immune-mediated and infectious stimuli and requires p38 activation

(2014) Francesca Mion et al.   MOLECULAR IMMUNOLOGY

Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells

(2014) Udaya S. Rangaswamy et al.   PLoS Pathogens

What goes up must come down: molecular basis of MAPKAP kinase 2/3-dependent regulation of the inflammatory response and its inhibition

(2013) Matthias Gaestel   BIOLOGICAL CHEMISTRY

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition

(2013) Feng Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors

(2013) Rand M. Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross Talk between the Akt and p38  Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

(2013) V. A. McGuire et al.   MOLECULAR AND CELLULAR BIOLOGY

Dectin-1 Regulates IL-10 Production via a MSK1/2 and CREB Dependent Pathway and Promotes the Induction of Regulatory Macrophage Markers

(2013) Suzanne E. Elcombe et al.   PLoS One

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

(2012) K. F. MacKenzie et al.   JOURNAL OF IMMUNOLOGY

p38  and p38  kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation

(2012) A. Risco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

(2012) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation and function of the RSK family of protein kinases

(2011) Yves Romeo et al.   BIOCHEMICAL JOURNAL

Characterization of the cellular action of the MSK inhibitor SB-747651A

(2011) Shaista Naqvi et al.   BIOCHEMICAL JOURNAL

The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production

(2011) Masanori Matsumoto et al.   IMMUNITY

B Cells Exposed to Enterobacterial Components Suppress Development of Experimental Colitis

(2011) Esben Gjerlff Wedebye Schmidt et al.   INFLAMMATORY BOWEL DISEASES

Distinct Functions of the Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinases MK2 and MK3

(2011) Christian Ehlting et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenosine Augments IL-10 Production by Microglial Cells through an A2B Adenosine Receptor-Mediated Process

(2011) B. Koscso et al.   JOURNAL OF IMMUNOLOGY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Regulatory B Cells (B10 Cells) and Regulatory T Cells Have Independent Roles in Controlling Experimental Autoimmune Encephalomyelitis Initiation and Late-Phase Immunopathogenesis

(2010) T. Matsushita et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

(2010) R. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Infant colitis—it's in the genes

(2010) Erik-Oliver Glocker et al.   LANCET

Discovery of a Small-Molecule Inhibitor of the KIX–KID Interaction

(2009) Bingbing X. Li et al.   CHEMBIOCHEM

Generation of a conditional CREB Ser133Ala knockin mouse

(2009) Andrew D. Wingate et al.   GENESIS

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

MSK activation and physiological roles

(2008) J. Simon et al.   Frontiers in Bioscience-Landmark

Strategies for use of IL-10 or its antagonists in human disease

(2008) Anne O'Garra et al.   IMMUNOLOGICAL REVIEWS

The kinase p38α serves cell type–specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expression

(2008) Chun Kim et al.   NATURE IMMUNOLOGY

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling

(2008) Olga Ananieva et al.   NATURE IMMUNOLOGY