Quantifying enzyme activity in living cells

Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dots

(2016) Carsten Marr et al.   CURRENT OPINION IN BIOTECHNOLOGY

Deciphering single cell metabolism by coherent Raman scattering microscopy

(2016) Shuhua Yue et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Characterization of proteins by in-cell NMR spectroscopy in cultured mammalian cells

(2016) Letizia Barbieri et al.   Nature Protocols

In-cell thermodynamics and a new role for protein surfaces

(2016) Austin E. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitrokcatmeasurements

(2016) Dan Davidi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitivity-Enhanced NMR Reveals Alterations in Protein Structure by Cellular Milieus

(2015) Kendra K. Frederick et al.   CELL

Thermodynamics of protein destabilization in live cells

(2015) Jens Danielsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the size dependence of macromolecular crowding shows that smaller is better

(2015) Kim A. Sharp   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What Macromolecular Crowding Can Do to a Protein

(2014) Irina Kuznetsova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Bacterial Cytoplasm Has Glass-like Properties and Is Fluidized by Metabolic Activity

(2013) Bradley R. Parry et al.   CELL

Commemorating the 1913 Michaelis-Menten paperDie Kinetik der Invertinwirkung: three perspectives

(2013) Ute Deichmann et al.   FEBS Journal

Formation of protein complexes in crowded environments - From in vitro to in vivo

(2013) Yael Phillip et al.   FEBS LETTERS

Contrasting Factors on the Kinetic Path to Protein Complex Formation Diminish the Effects of Crowding Agents

(2012) Yael Phillip et al.   BIOPHYSICAL JOURNAL

Whyin vivomay not equalin vitro- new effectors revealed by measurement of enzymatic activities under the samein vivo-like assay conditions

(2012) Rodolfo García-Contreras et al.   FEBS Journal

Protein-binding dynamics imaged in a living cell

(2012) Y. Phillip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What is the true enzyme kinetics in the biological system? An investigation of macromolecular crowding effect upon enzyme kinetics of glucose-6-phosphate dehydrogenase

(2011) Matthew G.S. Norris et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of β-Lactamase Enzyme Activity in Bacterial Lysates using MALDI-Mass Spectrometry

(2011) Gero P. Hooff et al.   JOURNAL OF PROTEOME RESEARCH

Stochastic Receptor Expression Determines Cell Fate upon Interferon Treatment

(2011) D. Levin et al.   MOLECULAR AND CELLULAR BIOLOGY

Measuring enzyme activity in single cells

(2011) Michelle L. Kovarik et al.   TRENDS IN BIOTECHNOLOGY

Measuring enzyme activities under standardized in vivo-like conditions for systems biology

(2010) Karen van Eunen et al.   FEBS Journal

BioNumbers—the database of key numbers in molecular and cell biology

(2009) Ron Milo et al.   NUCLEIC ACIDS RESEARCH