The coccidian parasites Toxoplasma and Neospora dysregulate mammalian lipid droplet biogenesis

Lipid droplet mobilization: The different ways to loosen the purse strings

(2016) Sabine D'Andrea   BIOCHIMIE

Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression

(2016) Philipp Olias et al.   Cell Host & Microbe

Toxoplasma gondiiTgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

(2016) Gabrielle Gay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Novel Secreted Protein, MYR1, Is Central to Toxoplasma ’s Manipulation of Host Cells

(2016) Magdalena Franco et al.   mBio

Lipid droplets form complexes with viroplasms and are crucial for rotavirus replication

(2016) Sue E Crawford et al.   Current Opinion in Virology

Host Lipid Bodies as Platforms for Intracellular Survival of Protozoan Parasites

(2016) Daniel A. M. Toledo et al.   Frontiers in Immunology

The cancer-promoting gene fatty acid-binding protein 5 (FABP5) is epigenetically regulated during human prostate carcinogenesis

(2015) K. Kawaguchi et al.   BIOCHEMICAL JOURNAL

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Lipid droplet–organelle interactions: emerging roles in lipid metabolism

(2015) Antonio Daniel Barbosa et al.   CURRENT OPINION IN CELL BIOLOGY

The life cycle of lipid droplets

(2015) Hayaa F Hashemi et al.   CURRENT OPINION IN CELL BIOLOGY

Epidermal Fatty Acid Binding Protein Promotes Skin Inflammation Induced by High-Fat Diet

(2015) Yuwen Zhang et al.   IMMUNITY

Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

(2015) Bethany R. Cartwright et al.   MOLECULAR BIOLOGY OF THE CELL

Infection by Toxoplasma gondii Specifically Induces Host c-Myc and the Genes This Pivotal Transcription Factor Regulates

(2014) Magdalena Franco et al.   EUKARYOTIC CELL

Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii

(2014) Laura Azeredo Miranda Mota et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

MAPK–PPARα/γ signal transduction pathways are involved in Chlamydia pneumoniae-induced macrophage-derived foam cell formation

(2014) Bei Cheng et al.   MICROBIAL PATHOGENESIS

Toxoplasma gondii-skeletal muscle cells interaction increases lipid droplet biogenesis and positively modulates the production of IL-12, IFN-g and PGE2

(2014) Alessandra F Gomes et al.   Parasites & Vectors

Rab18 is required for viral assembly of hepatitis C virus through trafficking of the core protein to lipid droplets

(2014) Hiromichi Dansako et al.   VIROLOGY

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

(2014) Daniel F. Markgraf et al.   Cell Reports

Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation

(2014) Karim Bensaad et al.   Cell Reports

Toxoplasma Effector MAF1 Mediates Recruitment of Host Mitochondria and Impacts the Host Response

(2014) Lena Pernas et al.   PLOS BIOLOGY

Forward Genetic Screening Identifies a Small Molecule That Blocks Toxoplasma gondii Growth by Inhibiting Both Host- and Parasite-Encoded Kinases

(2014) Kevin M. Brown et al.   PLoS Pathogens

Genetic Ablation of the Fatty Acid-Binding Protein FABP5 Suppresses HER2-Induced Mammary Tumorigenesis

(2013) L. Levi et al.   CANCER RESEARCH

Balancing the fat: lipid droplets and human disease

(2013) Natalie Krahmer et al.   EMBO Molecular Medicine

AToxoplasmadense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

(2013) Laurence Braun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole

(2013) Julia D. Romano et al.   MOLECULAR BIOLOGY OF THE CELL

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells

(2013) H. Zirath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reprogramming Neutral Lipid Metabolism in Mouse Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes

(2013) Hervé Lecoeur et al.   PLoS Neglected Tropical Diseases

Have It Your Way: How Polymorphic, Injected Kinases and Pseudokinases Enable Toxoplasma to Subvert Host Defenses

(2013) John C. Boothroyd   PLoS Pathogens

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

(2013) Luis Muniz-Feliciano et al.   PLoS Pathogens

Regulation of lipid stores and metabolism by lipophagy

(2012) K Liu et al.   CELL DEATH AND DIFFERENTIATION

Discovery of Potent and Selective Covalent Inhibitors of JNK

(2012) Tinghu Zhang et al.   CHEMISTRY & BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Modulation of innate immunity by Toxoplasma gondii virulence effectors

(2012) Christopher A. Hunter et al.   NATURE REVIEWS MICROBIOLOGY

A novel role for lipid droplets in the organismal antibacterial response

(2012) Preetha Anand et al.   eLife

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Toxoplasma gondii Induces B7-2 Expression through Activation of JNK Signal Transduction

(2011) Pedro Morgado et al.   INFECTION AND IMMUNITY

Hepatitis C Virus Core Protein Decreases Lipid Droplet Turnover

(2011) Charles Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages

(2011) Elma Aflaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets

(2011) Oludotun Adeyo et al.   JOURNAL OF CELL BIOLOGY

Strain-specific activation of the NF-κB pathway by GRA15, a novelToxoplasma gondiidense granule protein

(2011) Emily E. Rosowski et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TLR6-Driven Lipid Droplets in Mycobacterium leprae-Infected Schwann Cells: Immunoinflammatory Platforms Associated with Bacterial Persistence

(2011) K. A. Mattos et al.   JOURNAL OF IMMUNOLOGY

Not Just Fat: The Structure and Function of the Lipid Droplet

(2011) T. Fujimoto et al.   Cold Spring Harbor Perspectives in Biology

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

(2010) Prakash G. Chandak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty Acid-binding Protein 5 and PPARβ/δ Are Critical Mediators of Epidermal Growth Factor Receptor-induced Carcinoma Cell Growth

(2010) Padmamalini Kannan-Thulasiraman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxoplasma gondiiActivates Hypoxia-inducible Factor (HIF) by Stabilizing the HIF-1α Subunit via Type I Activin-like Receptor Kinase Receptor Signaling

(2010) Mandi Wiley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lutzomyia longipalpis Saliva Triggers Lipid Body Formation and Prostaglandin E2 Production in Murine Macrophages

(2010) Théo Araújo-Santos et al.   PLoS Neglected Tropical Diseases

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Thematic Review Series: Glycerolipids.DGAT enzymes and triacylglycerol biosynthesis

(2008) Chi-Liang Eric Yen et al.   JOURNAL OF LIPID RESEARCH

Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole

(2008) J. L. Cocchiaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA