Long-chain fatty acids inhibit human members of the aldo-keto reductase 1C subfamily

Inhibition of aldo-keto reductase family 1 member B10 by unsaturated fatty acids

(2016) Akira Hara et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Carbonyl reduction of warfarin: Identification and characterization of human warfarin reductases

(2016) Petra Malátková et al.   BIOCHEMICAL PHARMACOLOGY

In vitro metabolism of fenofibric acid by carbonyl reducing enzymes

(2016) Petra Malátková et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of n-3 and n-6 Polyunsaturated Fatty Acids on Microsomal P450 Steroidogenic Enzyme Activities and In Vitro Cortisol Production in Adrenal Tissue From Yorkshire Boars

(2016) Xuemei Xie et al.   ENDOCRINOLOGY

The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease

(2016) Natalie Jumper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Impact of nonsynonymous single nucleotide polymorphisms on in-vitro metabolism of exemestane by hepatic cytosolic reductases

(2016) Amity Platt et al.   Pharmacogenetics and Genomics

Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment

(2016) Li Huang et al.   Recent Patents on Anti-Cancer Drug Discovery

Potential Benefits of Omega-3 Fatty Acids in Non-Melanoma Skin Cancer

(2016) Homer Black et al.   Journal of Clinical Medicine

Omega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer Therapy

(2016) Donatella D’Eliseo et al.   Journal of Clinical Medicine

Aldo-keto reductase 1C1 induced by interleukin-1β mediates the invasive potential and drug resistance of metastatic bladder cancer cells

(2016) Ryuji Matsumoto et al.   Scientific Reports

Omega-3 polyunsaturated fatty acids and cancer: lessons learned from clinical trials

(2015) Seyed Fazel Nabavi et al.   CANCER AND METASTASIS REVIEWS

A new target for squamous cell skin cancer?

(2015) Dongwon Kim et al.   EXPERIMENTAL DERMATOLOGY

Do long-chain omega-3 fatty acids protect from atopic dermatitis?

(2015) Imke Reese et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism

(2014) Alon Mantel et al.   EXPERIMENTAL DERMATOLOGY

In vitrometabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism

(2014) Christian Atsriku et al.   XENOBIOTICA

Carbonyl reduction pathways in drug metabolism

(2013) Petra Malátková et al.   DRUG METABOLISM REVIEWS

Sepiapterin Reductase Mediates Chemical Redox Cycling in Lung Epithelial Cells

(2013) Shaojun Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of aldo–keto reductase family 1 (AKR1) enzymes in human steroid metabolism

(2013) Tea Lanišnik Rižner et al.   STEROIDS

Pathophysiological roles of aldo–keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers

(2012) Toshiyuki Matsunaga et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Development of Potent and Selective Inhibitors of Aldo–Keto Reductase 1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase) Based on N-Phenyl-Aminobenzoates and Their Structure–Activity Relationships

(2012) Adegoke O. Adeniji et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective Inhibition of Human Type-5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) by Baccharin, a Component of Brazilian Propolis

(2012) Satoshi Endo et al.   JOURNAL OF NATURAL PRODUCTS

Dual effects of N-acetyl-l-cysteine dependent on NQO1 activity: Suppressive or promotive of 9,10-phenanthrenequinone-induced toxicity

(2012) Tatsushi Toyooka et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Status of Fatty Acids as Skin Penetration Enhancers-A Review

(2012) Ashu Mittal et al.   Current Drug Delivery

Probing the inhibitor selectivity pocket of human 20α-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis

(2011) Ossama El-Kabbani et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aldo-Keto Reductase 1C3 Is Expressed in Differentiated Human Epidermis, Affects Keratinocyte Differentiation, and Is Upregulated in Atopic Dermatitis

(2011) Alon Mantel et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Fatty Acid (FFA) Transport in Cardiomyocytes Revealed by Imaging Unbound FFA Is Mediated by an FFA Pump Modulated by the CD36 Protein

(2010) Andrew N. Carley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipidomics reveals a remarkable diversity of lipids in human plasma,

(2010) Oswald Quehenberger et al.   JOURNAL OF LIPID RESEARCH

Inhibitors of human 20α-hydroxysteroid dehydrogenase (AKR1C1)

(2010) Ossama El-Kabbani et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): Overview and structural insights

(2010) Michael C. Byrns et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells

(2009) Toshiyuki Matsunaga et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase

(2008) Satoshi Endo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS

L-Xylulose reductase is involved in 9,10-phenanthrenequinone-induced apoptosis in human T lymphoma cells

(2008) Toshiyuki Matsunaga et al.   FREE RADICAL BIOLOGY AND MEDICINE

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies

(2007) Michael C. Byrns et al.   BIOCHEMICAL PHARMACOLOGY