A new target for squamous cell skin cancer?

Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism

(2014) Alon Mantel et al.   EXPERIMENTAL DERMATOLOGY

Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis through the Receptor, Gpr44

(2012) Amanda M. Nelson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Prostaglandin 15d-PGJ2Inhibits Androgen Receptor Signaling in Prostate Cancer Cells

(2012) Sanna Kaikkonen et al.   MOLECULAR ENDOCRINOLOGY

Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

(2012) L. A. Garza et al.   Science Translational Medicine

Aldo-Keto Reductase 1C3 Is Expressed in Differentiated Human Epidermis, Affects Keratinocyte Differentiation, and Is Upregulated in Atopic Dermatitis

(2011) Alon Mantel et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Histone Deacetylase Inhibitors and 15-Deoxy- 12,14-Prostaglandin J2 Synergistically Induce Apoptosis

(2010) M. Koyama et al.   CLINICAL CANCER RESEARCH

15-Deoxy-Δ 12,14 -prostaglandin J 2 upregulates the expression of heme oxygenase-1 and subsequently matrix metalloproteinase-1 in human breast cancer cells: possible roles of iron and ROS

(2009) Do-Hee Kim et al.   CARCINOGENESIS

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival

(2009) Yarí E. Marín et al.   EXPERIMENTAL DERMATOLOGY

Cyclo-oxygenase-2 Plays a Critical Role in UV-induced Skin Carcinogenesis

(2008) Joyce E. Rundhaug et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY