Binding of a biosynthetic intermediate to AtrA modulates the production of lidamycin byStreptomyces globisporus

SsaA, a Member of a Novel Class of Transcriptional Regulators, Controls Sansanmycin Production in Streptomyces sp. Strain SS through a Feedback Mechanism

(2013) Q. Li et al.   JOURNAL OF BACTERIOLOGY

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

(2013) Haruo Ikeda et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Draft Genome Sequence of Streptomyces globisporus C-1027, Which Produces an Antitumor Antibiotic Consisting of a Nine-Membered Enediyne with a Chromoprotein

(2012) L. Wang et al.   JOURNAL OF BACTERIOLOGY

Genome Context as a Predictive Tool for Identifying Regulatory Targets of the TetR Family Transcriptional Regulators

(2012) Sang Kyun Ahn et al.   PLoS One

Improvement of the Enediyne Antitumor Antibiotic C-1027 Production by Manipulating Its Biosynthetic Pathway Regulation inStreptomyces globisporus

(2011) Yihua Chen et al.   JOURNAL OF NATURAL PRODUCTS

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

(2011) Gilles P. van Wezel et al.   NATURAL PRODUCT REPORTS

Identification of a Nonaketide Product for the Iterative Polyketide Synthase in Biosynthesis of the Nine-Membered Enediyne C-1027

(2010) Xiaolei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027

(2010) Yihua Chen et al.   JOURNAL OF ANTIBIOTICS

“Pseudo” γ-Butyrolactone Receptors Respond to Antibiotic Signals to Coordinate Antibiotic Biosynthesis

(2010) Gangming Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The permease genenagE2is the key toN-acetylglucosamine sensing and utilization inStreptomyces coelicolorand is subject to multi-level control

(2010) Harald Nothaft et al.   MOLECULAR MICROBIOLOGY

Comparison of EMSA and SPR for the Characterization of RNA–RNase II Complexes

(2010) Rute G. Matos et al.   PROTEIN JOURNAL

Characterization and analysis of the regulatory network involved in control of lipomycin biosynthesis in Streptomyces aureofaciens Tü117

(2009) Liliya Horbal et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027

(2009) Lifei Wang et al.   BMC MICROBIOLOGY

Disruption ofcagA, the apoprotein gene of chromoprotein antibiotic C-1027, eliminates holo-antibiotic production, but not the cytotoxic chromophore

(2009) Zhihui Cui et al.   FEMS MICROBIOLOGY LETTERS

Transcriptomics analyses reveal global roles of the regulator AveI inStreptomyces avermitilis

(2009) Lei Chen et al.   FEMS MICROBIOLOGY LETTERS

Characterization of the SgcF Epoxide Hydrolase Supporting an (R)-Vicinal Diol Intermediate for Enediyne Antitumor Antibiotic C-1027 Biosynthesis

(2009) Shuangjun Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hierarchical control of virginiamycin production in Streptomyces virginiae by three pathway-specific regulators: VmsS, VmsT and VmsR

(2009) N. Pulsawat et al.   MICROBIOLOGY-SGM

Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator

(2009) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enediyne Anticancer Antibiotic Lidamycin: Chemistry, Biology and Pharmacology

(2008) Rong-guang Shao et al.   Anti-Cancer Agents in Medicinal Chemistry

Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165

(2008) Lei Chen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces

(2008) Sébastien Rigali et al.   EMBO REPORTS

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

(2008) Y. Ohnishi et al.   JOURNAL OF BACTERIOLOGY

Conditionally positive effect of the TetR-family transcriptional regulator AtrA on streptomycin production by Streptomyces griseus

(2008) S. Hirano et al.   MICROBIOLOGY-SGM

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

(2008) J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA