Muscle-specific and age-related changes in protein synthesis and protein degradation in response to hindlimb unloading in rats

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis

(2016) Leslie M. Baehr et al.   Aging-US

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

(2016) Catherine E. Winbanks et al.   Science Translational Medicine

Regrowth after skeletal muscle atrophy is impaired in aged rats, despite similar responses in signaling pathways

(2015) Jena R. White et al.   EXPERIMENTAL GERONTOLOGY

Therapeutic Approaches in Mitochondrial Dysfunction, Proteolysis, and Structural Alterations of Diaphragm and Gastrocnemius in Rats With Chronic Heart Failure

(2015) Esther Barreiro et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Skeletal muscle atrophy: disease-induced mechanisms may mask disuse atrophy

(2015) C. J. Malavaki et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle

(2015) Daniel W. D. West et al.   JOURNAL OF PHYSIOLOGY-LONDON

Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy

(2015) Giulia Milan et al.   Nature Communications

Rebuttal from Michael B. Reid, Andrew R. Judge and Sue C. Bodine

(2014) Michael B. Reid et al.   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk opposing view: The dominant mechanism causing disuse muscle atrophy is proteolysis

(2014) Michael B. Reid et al.   JOURNAL OF PHYSIOLOGY-LONDON

CrossTalk proposal: The dominant mechanism causing disuse muscle atrophy is decreased protein synthesis

(2014) Stuart M. Phillips et al.   JOURNAL OF PHYSIOLOGY-LONDON

Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression

(2014) Leslie M. Baehr et al.   Frontiers in Physiology

Neuromuscular electrical stimulation prevents muscle disuse atrophy during leg immobilization in humans

(2013) M. L. Dirks et al.   Acta Physiologica

Skeletal muscle atrophy during short-term disuse: Implications for age-related sarcopenia

(2013) Benjamin T. Wall et al.   AGEING RESEARCH REVIEWS

Skeletal muscle denervation causes skeletal muscle atrophy through a pathway that involves both Gadd45a and HDAC4

(2013) Kale S. Bongers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

MicroRNA in myogenesis and muscle atrophy

(2013) Xiaonan H. Wang   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Disuse-induced muscle wasting

(2013) Sue C. Bodine   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Chronic hypobaric hypoxia mediated skeletal muscle atrophy: role of ubiquitin–proteasome pathway and calpains

(2012) Pooja Chaudhary et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Longitudinal characterization of functional, morphologic, and biochemical adaptations in mouse skeletal muscle with hindlimb suspension

(2012) Andrea M. Hanson et al.   MUSCLE & NERVE

Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

(2012) Sharon L. Rowan et al.   PLoS One

Translational Suppression of Atrophic Regulators by MicroRNA-23a Integrates Resistance to Skeletal Muscle Atrophy

(2011) Shogo Wada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids

(2011) Leslie M. Baehr et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sarcopenia Accelerates at Advanced Ages in Fisher 344xBrown Norway Rats

(2011) E. B. Lushaj et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3

(2011) Chia-Ling Wu et al.   PLoS One

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

(2010) Viviana Moresi et al.   CELL

Effects of 3 days unloading on molecular regulators of muscle size in humans

(2010) T. Gustafsson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy

(2010) M. J. Rennie et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Proteolysis activation and proteome alterations in murine skeletal muscle submitted to 1 week of hindlimb suspension

(2009) Rita Ferreira et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Differential atrophy of the lower-limb musculature during prolonged bed-rest

(2009) Daniel L. Belavý et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Artificial gravity maintains skeletal muscle protein synthesis during 21 days of simulated microgravity

(2009) T. B. Symons et al.   JOURNAL OF APPLIED PHYSIOLOGY

Effects of aging on human skeletal muscle after immobilization and retraining

(2009) C. Suetta et al.   JOURNAL OF APPLIED PHYSIOLOGY

Age-Related Deficit in Load-Induced Skeletal Muscle Growth

(2009) D. T. Hwee et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy

(2008) Emilie Vazeille et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The glucocorticoid receptor and FOXO1 synergistically activate the skeletal muscle atrophy-associated MuRF1 gene

(2008) David S. Waddell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle

(2008) Thomas C. Vary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Targeting Proteins for Destruction by the Ubiquitin System: Implications for Human Pathobiology

(2008) Alan L. Schwartz et al.   Annual Review of Pharmacology and Toxicology

Skeletal muscle proteolysis in response to short-term unloading in humans

(2008) Per A. Tesch et al.   JOURNAL OF APPLIED PHYSIOLOGY

Effect of unloading followed by reloading on expression of collagen and related growth factors in rat tendon and muscle

(2008) K. M. Heinemeier et al.   JOURNAL OF APPLIED PHYSIOLOGY