In vitro and in vivo efficacies of novel carbazole aminoalcohols in the treatment of cystic echinococcosis

Carbazole Aminoalcohols Induce Antiproliferation and Apoptosis of Human Tumor Cells by Inhibiting Topoisomerase I

(2016) Weisi Wang et al.   ChemMedChem

Biological potential of carbazole derivatives

(2015) Agata Głuszyńska   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Topoisomerase II from Human Malaria Parasites

(2015) Devaraja G. Mudeppa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo activity of albendazole in combination with thymol against Echinococcus multilocularis

(2015) Clara María Albani et al.   VETERINARY PARASITOLOGY

In vitro effect of 5-fluorouracil and paclitaxel on Echinococcus granulosus larvae and cells

(2014) P.E. Pensel et al.   ACTA TROPICA

In VitroandIn VivoEffects of Tamoxifen against Larval Stage Echinococcus granulosus

(2014) María Celeste Nicolao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activities of fenbendazole in comparison with albendazole against Echinococcus multilocularis metacestodes in vitro and in a murine infection model

(2014) Tatiana Küster et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Nanocurcumin: a novel antifilarial agent with DNA topoisomerase II inhibitory activity

(2014) Mohammad Ali et al.   JOURNAL OF DRUG TARGETING

1,4-Disubstituted Thiosemicarbazide Derivatives are Potent Inhibitors of Toxoplasma gondii Proliferation

(2014) Katarzyna Dzitko et al.   MOLECULES

Theoretical and Experimental Studies of New Modified Isoflavonoids as Potential Inhibitors of Topoisomerase I from Plasmodium falciparum

(2014) Wilian A. Cortopassi et al.   PLoS One

Profound Activity of the Anti-cancer Drug Bortezomib against Echinococcus multilocularis Metacestodes Identifies the Proteasome as a Novel Drug Target for Cestodes

(2014) Britta Stadelmann et al.   PLoS Neglected Tropical Diseases

New Mechanistic and Functional Insights into DNA Topoisomerases

(2013) Stefanie Hartman Chen et al.   Annual Review of Biochemistry

Gimatecan and other camptothecin derivatives poison Leishmania DNA-topoisomerase IB leading to a strong leishmanicidal effect

(2013) Christopher F. Prada et al.   BIOCHEMICAL PHARMACOLOGY

The lignan glycosides lyoniside and saracoside poison the unusual type IB topoisomerase of Leishmania donovani and kill the parasite both in vitro and in vivo

(2013) Sourav Saha et al.   BIOCHEMICAL PHARMACOLOGY

The genome of the hydatid tapeworm Echinococcus granulosus

(2013) Huajun Zheng et al.   NATURE GENETICS

Drugging Topoisomerases: Lessons and Challenges

(2012) Yves Pommier   ACS Chemical Biology

Occurrence, Biogenesis, and Synthesis of Biologically Active Carbazole Alkaloids

(2012) Arndt W. Schmidt et al.   CHEMICAL REVIEWS

In vitro efficacy of the anticancer drug imatinib on Echinococcus multilocularis larvae

(2012) Sarah Hemer et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A New Promising Application for Highly Cytotoxic Metal Compounds: η6-Areneruthenium(II) Phosphite Complexes for the Treatment of Alveolar Echinococcosis

(2012) Tatiana Küster et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diagnosis, treatment, and management of echinococcosis

(2012) D. P. McManus et al.   BMJ-British Medical Journal

Clinical features and treatment of alveolar echinococcosis

(2010) Peter Kern   CURRENT OPINION IN INFECTIOUS DISEASES

Newly Identified Antibacterial Compounds Are Topoisomerase Poisons in African Trypanosomes

(2009) S. C. Tang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of anti-sleeping-sickness drugs and topoisomerase inhibitors in combination on Trypanosoma brucei

(2009) D. Steverding et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: Antiparasitic activities of p38 MAPK inhibitors

(2008) Verena Gelmedin et al.   BIOCHEMICAL PHARMACOLOGY

In vitro and in vivo effects of 2-methoxyestradiol, either alone or combined with albendazole, against Echinococcus metacestodes

(2008) Martin Spicher et al.   EXPERIMENTAL PARASITOLOGY