Apolipoprotein E Isoforms Differentially Regulate Alzheimer’s Disease and Amyloid-β-Induced Inflammatory Response in vivo and in vitro

Negative Regulation of AβPP Gene Expression by Pur-alpha

(2017) Nune Darbinian et al.   JOURNAL OF ALZHEIMERS DISEASE

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1)

(2015) Hyesoon Kim et al.   Oncotarget

Interleukin-1β Promotes Ovarian Tumorigenesis through a p53/NF-κB-Mediated Inflammatory Response in Stromal Fibroblasts

(2015) Isaiah Gregory Schauer et al.   NEOPLASIA

APOEgenotype-dependent modulation of astrocyte chemokine CCL3 production

(2014) Eiron Cudaback et al.   GLIA

Amyloid-β Pathology andAPOEGenotype Modulate Retinoid X Receptor Agonist Activityin Vivo

(2014) Leon M. Tai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease

(2014) Evan Dorey et al.   Neuroscience Bulletin

Metabolic Stress Modulates Alzheimer’s β-Secretase Gene Transcription via SIRT1-PPARγ-PGC-1 in Neurons

(2013) Ruishan Wang et al.   Cell Metabolism

Vitamin D Enhances Glucocorticoid Action in Human Monocytes

(2013) Yong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

1,25-Dihydroxyvitamin D Promotes Negative Feedback Regulation of TLR Signaling via Targeting MicroRNA-155-SOCS1 in Macrophages

(2013) Y. Chen et al.   JOURNAL OF IMMUNOLOGY

Regulation of prostaglandin F2α against β amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia

(2013) Jingjing Zhuang et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Retinoid X receptors in macrophage biology

(2013) Tamás Rőszer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Effectiveness of the Combination of Memantine Plus Vitamin D on Cognition in Patients With Alzheimer Disease

(2012) Cédric Annweiler et al.   Cognitive and Behavioral Neurology

Vitamin D Inhibits Monocyte/Macrophage Proinflammatory Cytokine Production by Targeting MAPK Phosphatase-1

(2012) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg-SwDI transgenic mice

(2012) Yu Zeng et al.   JOURNAL OF NEUROCHEMISTRY

Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent A  Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice

(2012) N. Bien-Ly et al.   JOURNAL OF NEUROSCIENCE

Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor- -Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease

(2012) S. Mandrekar-Colucci et al.   JOURNAL OF NEUROSCIENCE

Transforming growth factor-β stimulates β amyloid uptake by microglia through Smad3-dependent mechanisms

(2012) Juan E. Tichauer et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Vitamin D receptor and Alzheimer's disease: a genetic and functional study

(2012) Liyong Wang et al.   NEUROBIOLOGY OF AGING

Vitamin D Receptor Gene Haplotype Is Associated with Late-Onset Alzheimer's Disease

(2012) Duygu Gezen-Ak et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Impact and Therapeutic Potential of PPARs in Alzheimers Disease

(2011) Michael T. Heneka et al.   Current Neuropharmacology

Effects of sex hormones on Alzheimer's disease-associated β-amyloid oligomer formation in vitro

(2011) Akiyoshi Morinaga et al.   EXPERIMENTAL NEUROLOGY

APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans

(2011) Patricia Huebbe et al.   FASEB JOURNAL

The ER stress factor XBP1s prevents amyloid-β neurotoxicity

(2011) Sergio Casas-Tinto et al.   HUMAN MOLECULAR GENETICS

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

(2011) E Genin et al.   MOLECULAR PSYCHIATRY

The vitamin D receptor gene is associated with Alzheimer's disease

(2011) Donald J. Lehmann et al.   NEUROSCIENCE LETTERS

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease

(2011) Huaqi Xiong et al.   Neuroscience Bulletin

Apolipoprotein A-I Deficiency Increases Cerebral Amyloid Angiopathy and Cognitive Deficits in APP/PS1ΔE9 Mice

(2010) Iliya Lefterov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyk2/STAT3 Signaling Mediates  -Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease

(2010) J. Wan et al.   JOURNAL OF NEUROSCIENCE

Uncovering Molecular Biomarkers That Correlate Cognitive Decline with the Changes of Hippocampus' Gene Expression Profiles in Alzheimer's Disease

(2010) Martín Gómez Ravetti et al.   PLoS One

A Common Biological Mechanism in Cancer and Alzheimers Disease?

(2009) M. Behrens et al.   Current Alzheimer Research

Protective actions of sex steroid hormones in Alzheimer’s disease

(2009) Christian J. Pike et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Human APOE Isoform-Dependent Effects on Brain  -Amyloid Levels in PDAPP Transgenic Mice

(2009) K. R. Bales et al.   JOURNAL OF NEUROSCIENCE

ApoE isoform-dependent changes in hippocampal synaptic function

(2009) Kimberly M Korwek et al.   Molecular Neurodegeneration

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy

(2009) Guojun Bu   NATURE REVIEWS NEUROSCIENCE

Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway

(2009) Vanja Vukic et al.   NEUROBIOLOGY OF DISEASE

Vitamin D, a neuro-immunomodulator: Implications for neurodegenerative and autoimmune diseases

(2009) D.A. Fernandes de Abreu et al.   PSYCHONEUROENDOCRINOLOGY

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Impact of Apolipoprotein E (ApoE) Polymorphism on Brain ApoE Levels

(2008) D. R. Riddell et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons

(2008) T Chiba et al.   MOLECULAR PSYCHIATRY

ApoE Promotes the Proteolytic Degradation of Aβ

(2008) Qingguang Jiang et al.   NEURON

Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

(2008) Mark R Haussler et al.   NUTRITION REVIEWS

The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol

(2007) Candice M. Brown et al.   NEUROBIOLOGY OF AGING

APOE genotype-specific differences in the innate immune response

(2007) Michael P. Vitek et al.   NEUROBIOLOGY OF AGING