Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome

Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

(2016) Shiwu Zhang et al.   Stem Cells International

Linking genomic reorganization to tumor initiation via the giant cell cycle

(2016) N Niu et al.   Oncogenesis

Radiation-induced homotypic cell fusions of innately resistant glioblastoma cells mediate their sustained survival and recurrence

(2015) E. Kaur et al.   CARCINOGENESIS

OCT4A and the DNA damage response

(2015) David Murray et al.   CELL CYCLE

Pitfalls of the MTT assay: Direct and off-target effects of inhibitors can result in over/underestimation of cell viability

(2015) A.A. Stepanenko et al.   GENE

Beyond genomics: Critical evaluation of cell line utility for ovarian cancer research

(2015) Kevin M. Elias et al.   GYNECOLOGIC ONCOLOGY

Spontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression

(2015) Razmik Mirzayans et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer

(2015) Fei Fei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

A fast Resazurin-based live viability assay is equivalent to the MTT-test in the KeratinoSens assay

(2015) Roger Emter et al.   TOXICOLOGY IN VITRO

Use of the viability reagent PrestoBlue in comparison with alamarBlue and MTT to assess the viability of human corneal epithelial cells

(2015) Manlong Xu et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Polyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor

(2014) Hongcheng Lv et al.   BMC CANCER

Genome wide expression analysis of radiation-induced DNA damage responses in isogenic HCT116 p53+/+ and HCT116 p53−/− colorectal carcinoma cell lines

(2014) Theres Lindgren et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal

(2013) Jekaterina Erenpreisa et al.   Cancer Cell International

Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status

(2013) Razmik Mirzayans et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation of cancer stem-like cells through the formation of polyploid giant cancer cells

(2013) S Zhang et al.   ONCOGENE

iTRAQ-Based Proteomic Analysis of Polyploid Giant Cancer Cells and Budding Progeny Cells Reveals Several Distinct Pathways for Ovarian Cancer Development

(2013) Shiwu Zhang et al.   PLoS One

Comparison of PrestoBlue and MTT assays of cellular viability in the assessment of anti-proliferative effects of plant extracts on human endothelial cells

(2013) Magdalena Boncler et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Mechanisms of Metastatic Tumor Dormancy

(2013) Mary Osisami et al.   Journal of Clinical Medicine

p21WAF1 and tumourigenesis

(2012) Noel A. Warfel et al.   CURRENT OPINION IN ONCOLOGY

New Insights into p53 Signaling and Cancer Cell Response to DNA Damage: Implications for Cancer Therapy

(2012) Razmik Mirzayans et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Radiation-Induced Reprogramming of Breast Cancer Cells

(2012) Chann Lagadec et al.   STEM CELLS

Formation of solid tumors by a single multinucleated cancer cell

(2011) Zhang Weihua et al.   CANCER

EGF Receptor Inhibition Radiosensitizes NSCLC Cells by Inducing Senescence in Cells Sustaining DNA Double-Strand Breaks

(2011) M. Wang et al.   CANCER RESEARCH

Polyploid tumour cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagic degradation

(2011) Jekaterina Erenpreisa et al.   CELL BIOLOGY INTERNATIONAL

Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

(2011) Valentina Zuco et al.   PLoS One

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

(2010) Ilio Vitale et al.   EMBO JOURNAL

MOS, aneuploidy and the ploidy cycle of cancer cells

(2010) J Erenpreisa et al.   ONCOGENE

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

(2008) Pierre-Emmanuel Puig et al.   CELL BIOLOGY INTERNATIONAL

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

In vitro assays for the evaluation of drug resistance in tumor cells

(2008) Jozef Hatok et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Dichloroacetate induces apoptosis in endometrial cancer cells

(2008) Jason Y.Y. Wong et al.   GYNECOLOGIC ONCOLOGY

Ultraviolet light exposure triggers nuclear accumulation of p21WAF1and accelerated senescence in human normal and nucleotide excision repair-deficient fibroblast strains

(2007) Razmik Mirzayans et al.   JOURNAL OF CELLULAR PHYSIOLOGY