Mechanisms of Metastatic Tumor Dormancy

Cell cycle arrest is not senescence

(2016) Mikhail V. Blagosklonny   Aging-US

GAS6/AXL Axis Regulates Prostate Cancer Invasion, Proliferation, and Survival in the Bone Marrow Niche

(2015) Yusuke Shiozawa et al.   NEOPLASIA

The Iron-Regulated Metastasis Suppressor NDRG1 Targets NEDD4L, PTEN, and SMAD4 and Inhibits the PI3K and Ras Signaling Pathways

(2012) Zaklina Kovacevic et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression of tumour-specific antigens underlies cancer immunoediting

(2012) Michel DuPage et al.   NATURE

Dormancy Signatures and Metastasis in Estrogen Receptor Positive and Negative Breast Cancer

(2012) Ryung S. Kim et al.   PLoS One

Prospective Identification of Glioblastoma Cells Generating Dormant Tumors

(2012) Ronit Satchi-Fainaro et al.   PLoS One

Consensus Micro RNAs Governing the Switch of Dormant Tumors to the Fast-Growing Angiogenic Phenotype

(2012) Nava Almog et al.   PLoS One

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

(2012) O. Straume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Hematopoietic Stem Cell Aging, Life Span, and Transplantation

(2012) Gary Van Zant et al.   Stem Cells Translational Medicine

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Cancer-Associated Adipocytes Exhibit an Activated Phenotype and Contribute to Breast Cancer Invasion

(2011) B. Dirat et al.   CANCER RESEARCH

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells

(2011) Linda S. Steelman et al.   CELL CYCLE

 1-Integrin: A Potential Therapeutic Target in the Battle against Cancer Recurrence

(2011) D. Barkan et al.   CLINICAL CANCER RESEARCH

Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication

(2011) Sergio A. Quezada et al.   IMMUNOLOGICAL REVIEWS

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

(2011) Dipak Panigrahy et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone morphogenetic protein 7 in dormancy and metastasis of prostate cancer stem-like cells in bone

(2011) Aya Kobayashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

The tumor-suppressor gene ARHI (DIRAS3) suppresses ovarian cancer cell migration through inhibition of the Stat3 and FAK/Rho signaling pathways

(2011) D B Badgwell et al.   ONCOGENE

Controversies in clinical cancer dormancy

(2011) J. W. Uhr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Slow-Cycling Therapy-Resistant Cancer Cells

(2011) Nathan Moore et al.   STEM CELLS AND DEVELOPMENT

The Incidence of Cancer in a Population-Based Cohort of Canadian Heart Transplant Recipients

(2010) Y. Jiang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Cellular quiescence caused by the Mdm2 inhibitor Nutlin-3A

(2010) Lioubov G. Korotchkina et al.   CELL CYCLE

Review Article: Epoxyeicosatrienoic Acids: Novel Mediators of Cardioprotection

(2010) Kasem Nithipatikom et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Stem cells in cancer: instigators and propagators?

(2010) M. R. Alison et al.   JOURNAL OF CELL SCIENCE

Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma

(2010) Jo Eyles et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of Obesity on Prognosis After Early-Stage Breast Cancer

(2010) Marianne Ewertz et al.   JOURNAL OF CLINICAL ONCOLOGY

Circulating tumour cells in clinical practice: Methods of detection and possible characterization

(2010) Marianna Alunni-Fabbroni et al.   METHODS

Site-specific metastasis formation

(2010) Adit Ben-Baruch   Cell Adhesion & Migration

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Incidence of and Risk Factors for Skin Cancer After Heart Transplant

(2009) Jerry D. Brewer et al.   ARCHIVES OF DERMATOLOGY

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

EpCAM, a human tumor-associated antigen promotes Th2 development and tumor immune evasion

(2009) A. Ziegler et al.   BLOOD

Transcriptional Switch of Dormant Tumors to Fast-Growing Angiogenic Phenotype

(2009) N. Almog et al.   CANCER RESEARCH

Cancer Stem Cells and Aneuploid Populations within Developing Tumors Are the Major Determinants of Tumor Dormancy

(2009) A. P. Kusumbe et al.   CANCER RESEARCH

Computational Identification of a p38SAPK-Regulated Transcription Factor Network Required for Tumor Cell Quiescence

(2009) A. P. Adam et al.   CANCER RESEARCH

Comparison of de novo tumours after liver transplantation with incidence rates from Italian cancer registries

(2009) U. Baccarani et al.   DIGESTIVE AND LIVER DISEASE

Obesity and Breast Cancer: The Estrogen Connection

(2009) Margot P. Cleary et al.   ENDOCRINOLOGY

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Organ Recipients Suffering From Undifferentiated Neuroendocrine Small-Cell Carcinoma of Donor Origin: A Case Report

(2009) D. Foltys et al.   TRANSPLANTATION PROCEEDINGS

Tumor dormancy and immunoescape 

(2008) BRUNO QUESNEL   APMIS

The role of metastasis suppressor genes in metastatic dormancy 

(2008) CHRISTINE E. HORAK et al.   APMIS

TNFR1 Signaling and IFN-γ Signaling Determine whether T Cells Induce Tumor Dormancy or Promote Multistage Carcinogenesis

(2008) Nele Müller-Hermelink et al.   CANCER CELL

Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

(2008) D. Barkan et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Extracellular matrix regulation of autophagy

(2008) Rebecca Lock et al.   CURRENT OPINION IN CELL BIOLOGY

IFN-γ– and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers

(2008) Bin Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Attributes of adult stem cells

(2008) MR Alison et al.   JOURNAL OF PATHOLOGY

ATF6 -Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo

(2008) D. M. Schewe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL