Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs)

Molecular pathogenesis and therapeutic implications in pediatric high-grade gliomas

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Pediatric Gliomas: Current Concepts on Diagnosis, Biology, and Clinical Management

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Pediatric high-grade glioma: current molecular landscape and therapeutic approaches

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β-Arrestin1/miR-326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest

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Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas

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MicroRNAs-Proteomic Networks Characterizing Human Medulloblastoma-SLCs

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Inhibition of the NOTCH pathway using γ-secretase inhibitor RO4929097 has limited antitumor activity in established glial tumors

(2015) Carmela Dantas-Barbosa et al.   ANTI-CANCER DRUGS

Genome-wide small noncoding RNA profiling of pediatric high-grade gliomas reveals deregulation of several miRNAs, identifies downregulation of snoRNA cluster HBII-52 and delineates H3F3A and TP53 mutant-specific miRNAs and snoRNAs

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Tumor suppressor miR-181c attenuates proliferation, invasion, and self-renewal abilities in glioblastoma

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Decreased expression of microRNA-107 predicts poorer prognosis in glioma

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Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy

(2014) Juntao Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reductions in the expression of miR-124-3p, miR-128-1, and miR-221-3p in pediatric astrocytomas are related to high-grade supratentorial, and recurrent tumors in Mexican children

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Heat shock protein 47 regulated by miR-29a to enhance glioma tumor growth and invasion

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Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo

(2014) XUEZHEN LI et al.   Molecular Medicine Reports

Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase

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MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression

(2013) Lei Chen et al.   JOURNAL OF NEURO-ONCOLOGY

MiR-92b inhibitor promoted glioma cell apoptosis via targeting DKK3 and blocking the Wnt/beta-catenin signaling pathway

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High-throughput microRNA profiling of pediatric high-grade gliomas

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The Different Role of Notch1 and Notch2 in Astrocytic Gliomas

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Phase I Trial of MK-0752 in Children With Refractory CNS Malignancies: A Pediatric Brain Tumor Consortium Study

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Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis

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Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

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The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

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The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo

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Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development

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Notch Signaling in Leukemia

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