Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma
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Title
Noncanonical GLI1 signaling promotes stemness features and in vivo growth in lung adenocarcinoma
Authors
Keywords
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Journal
ONCOGENE
Volume 36, Issue 32, Pages 4641-4652
Publisher
Springer Nature
Online
2017-04-04
DOI
10.1038/onc.2017.91
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Note: Only part of the references are listed.- Vismodegib or cixutumumab in combination with standard chemotherapy for patients with extensive-stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E1508)
- (2016) Chandra P. Belani et al. CANCER
- Hedgehog signalling
- (2016) Raymond Teck Ho Lee et al. DEVELOPMENT
- Prognostic role of Gli1 expression in solid malignancies: a meta-analysis
- (2016) Ji Cheng et al. Scientific Reports
- Intra-tumoral heterogeneity in the expression of programmed-death (PD) ligands in isogeneic primary and metastatic lung cancer: Implications for immunotherapy
- (2016) David J. Pinato et al. OncoImmunology
- Molecular Pathways: Novel Approaches for Improved Therapeutic Targeting of Hedgehog Signaling in Cancer Stem Cells
- (2015) Verline Justilien et al. CLINICAL CANCER RESEARCH
- Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth
- (2015) Davide D’Amico et al. DEVELOPMENTAL CELL
- Proteomic analysis of human sonic hedgehog (SHH) medulloblastoma stem-like cells
- (2015) Maurizio Ronci et al. Molecular BioSystems
- Refining the treatment of NSCLC according to histological and molecular subtypes
- (2015) Anish Thomas et al. Nature Reviews Clinical Oncology
- Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer
- (2015) G Sette et al. Cell Death & Disease
- Targeting the Hedgehog signaling pathway in cancer: beyond Smoothened
- (2015) Annelies Gonnissen et al. Oncotarget
- Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding
- (2015) Akwasi Agyeman et al. Oncotarget
- The PRKCI and SOX2 Oncogenes Are Coamplified and Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell Carcinoma
- (2014) Verline Justilien et al. CANCER CELL
- Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer
- (2014) L. Huang et al. CLINICAL CANCER RESEARCH
- Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
- (2014) P. Infante et al. EMBO JOURNAL
- Setting the Bar for Therapeutic Trials in Non–Small-Cell Lung Cancer: How Low Can We Go?
- (2014) David H. Johnson JOURNAL OF CLINICAL ONCOLOGY
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Differential in vivo tumorigenicity of diverse KRAS mutations in vertebrate pancreas: A comprehensive survey
- (2014) J T Park et al. ONCOGENE
- Concise Reviews: Cancer Stem Cells: From Concept to Cure
- (2014) K. B. Matchett et al. STEM CELLS
- The effects of sonic hedgehog signaling pathway components on non-small-cell lung cancer progression and clinical outcome
- (2014) Jinwook Hwang et al. World Journal of Surgical Oncology
- ABC transporters in CSCs membranes as a novel target for treating tumor relapse
- (2014) Laura Zinzi et al. Frontiers in Pharmacology
- Neuropilin-2 Is Upregulated in Lung Cancer Cells during TGF- 1-Induced Epithelial-Mesenchymal Transition
- (2013) P. Nasarre et al. CANCER RESEARCH
- GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation
- (2013) Hira Lal Goel et al. EMBO Molecular Medicine
- Loss of the Transcription Factor GLI1 Identifies a Signaling Network in the Tumor Microenvironment Mediating KRAS Oncogene-induced Transformation
- (2013) Lisa D. Mills et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas
- (2013) Scott X. Atwood et al. NATURE
- Unraveling the therapeutic potential of the Hedgehog pathway in cancer
- (2013) Dereck Amakye et al. NATURE MEDICINE
- Gli1 Mediates Lung Cancer Cell Proliferation and Sonic Hedgehog-Dependent Mesenchymal Cell Activation
- (2013) Olga Bermudez et al. PLoS One
- Neuropilin-1 is expressed by breast cancer stem-like cells and is linked to NF-κB activation and tumor sphere formation
- (2012) Yelena Glinka et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Crosstalk of mTOR/S6K1 and Hedgehog Pathways
- (2012) Yan Wang et al. CANCER CELL
- Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
- (2012) Petra Hamerlik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Hedgehog processing pathway is required for NSCLC growth and survival
- (2012) J Rodriguez-Blanco et al. ONCOGENE
- Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity
- (2011) S. Singh et al. CANCER RESEARCH
- Hedgehog signaling pathway molecules and ALDH1A1 expression in early-stage non-small cell lung cancer
- (2011) Guy Raz et al. LUNG CANCER
- Methyl-CpG binding column-based identification of nine genes hypermethylated in colorectal cancer
- (2011) Paulina Kober et al. MOLECULAR CARCINOGENESIS
- A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours
- (2011) Benjamin Beck et al. NATURE
- A crucial requirement for Hedgehog signaling in small cell lung cancer
- (2011) Kwon-Sik Park et al. NATURE MEDICINE
- Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells
- (2011) X Cao et al. ONCOGENE
- ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
- (2011) R R Singh et al. ONCOGENE
- Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling
- (2010) J. P. Sullivan et al. CANCER RESEARCH
- Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation
- (2010) S.-H. Chiou et al. CANCER RESEARCH
- Hedgehog controls neural stem cells through p53-independent regulation of Nanog
- (2010) Agnese Po et al. EMBO JOURNAL
- NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53
- (2010) Marie Zbinden et al. EMBO JOURNAL
- Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas
- (2010) Frédéric Varnat et al. EMBO Molecular Medicine
- Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway
- (2010) Elspeth M. Beauchamp et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer stem cells: a new framework for the design of tumor therapies
- (2010) Boyan K. Garvalov et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
- (2010) Gianluca Canettieri et al. NATURE CELL BIOLOGY
- A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival
- (2009) Anurag Singh et al. CANCER CELL
- Paracrine Hedgehog Signaling in Cancer
- (2009) J.-W. Theunissen et al. CANCER RESEARCH
- Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation
- (2009) Y. Katoh et al. CURRENT MOLECULAR MEDICINE
- GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation
- (2009) O. Nolan-Stevaux et al. GENES & DEVELOPMENT
- Aldehyde Dehydrogenase 1 Is a Tumor Stem Cell-Associated Marker in Lung Cancer
- (2009) F. Jiang et al. MOLECULAR CANCER RESEARCH
- Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer
- (2009) Motoko Seto et al. MOLECULAR CARCINOGENESIS
- Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis
- (2008) Maresa Caunt et al. CANCER CELL
- Hedgehog: functions and mechanisms
- (2008) M. Varjosalo et al. GENES & DEVELOPMENT
- Somatic mutations affect key pathways in lung adenocarcinoma
- (2008) Li Ding et al. NATURE
- Zfp143 RegulatesNanogThrough Modulation of Oct4 Binding
- (2008) Xi Chen et al. STEM CELLS
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