Do Multiwell Plate High Throughput Assays Measure Loss of Cell Viability Following Exposure to Genotoxic Agents?

Impact of Premature Senescence on Radiosensitivity Measured by High Throughput Cell-Based Assays

(2017) Razmik Mirzayans et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multinucleated Giant Cancer Cells Produced in Response to Ionizing Radiation Retain Viability and Replicate Their Genome

(2017) Razmik Mirzayans et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Guidelines for the selection of functional assays to evaluate the hallmarks of cancer

(2016) Otília Menyhárt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Morphological and Functional Characteristic of Senescent Cancer Cells

(2016) Ewa Sikora et al.   CURRENT DRUG TARGETS

Improving anticancer drug development begins with cell culture: misinformation perpetrated by the misuse of cytotoxicity assays

(2016) Alan Eastman   Oncotarget

Tumor Budding, Micropapillary Pattern, and Polyploidy Giant Cancer Cells in Colorectal Cancer: Current Status and Future Prospects

(2016) Shiwu Zhang et al.   Stem Cells International

Linking genomic reorganization to tumor initiation via the giant cell cycle

(2016) N Niu et al.   Oncogenesis

The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells

(2015) Luis Jaime Castro-Vega et al.   CARCINOGENESIS

Radiation-induced homotypic cell fusions of innately resistant glioblastoma cells mediate their sustained survival and recurrence

(2015) E. Kaur et al.   CARCINOGENESIS

Pitfalls of the MTT assay: Direct and off-target effects of inhibitors can result in over/underestimation of cell viability

(2015) A.A. Stepanenko et al.   GENE

The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer

(2015) Fei Fei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cyclic Pifithrin-α Sensitizes Wild Type p53 Tumor Cells to Antimicrotubule Agent–Induced Apoptosis

(2015) Valentina Zuco et al.   NEOPLASIA

Polyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor

(2014) Hongcheng Lv et al.   BMC CANCER

Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer

(2014) Jermaine Coward et al.   Frontiers in Oncology

Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal

(2013) Jekaterina Erenpreisa et al.   Cancer Cell International

Vital dyes and virtual deaths

(2013) M Husmann   CELL DEATH AND DIFFERENTIATION

Generation of cancer stem-like cells through the formation of polyploid giant cancer cells

(2013) S Zhang et al.   ONCOGENE

iTRAQ-Based Proteomic Analysis of Polyploid Giant Cancer Cells and Budding Progeny Cells Reveals Several Distinct Pathways for Ovarian Cancer Development

(2013) Shiwu Zhang et al.   PLoS One

Mechanisms of Metastatic Tumor Dormancy

(2013) Mary Osisami et al.   Journal of Clinical Medicine

Radiation-Induced Reprogramming of Breast Cancer Cells

(2012) Chann Lagadec et al.   STEM CELLS

Formation of solid tumors by a single multinucleated cancer cell

(2011) Zhang Weihua et al.   CANCER

Polyploid tumour cells elicit paradiploid progeny through depolyploidizing divisions and regulated autophagic degradation

(2011) Jekaterina Erenpreisa et al.   CELL BIOLOGY INTERNATIONAL

Synergistic Antitumor Effects of Novel HDAC Inhibitors and Paclitaxel In Vitro and In Vivo

(2011) Valentina Zuco et al.   PLoS One

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Senescent cells as a source of inflammatory factors for tumor progression

(2010) Albert R. Davalos et al.   CANCER AND METASTASIS REVIEWS

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

(2010) Ilio Vitale et al.   EMBO JOURNAL

MOS, aneuploidy and the ploidy cycle of cancer cells

(2010) J Erenpreisa et al.   ONCOGENE

Limitations of MTT and MTS-Based Assays for Measurement of Antiproliferative Activity of Green Tea Polyphenols

(2010) Piwen Wang et al.   PLoS One

Interference of magnesium corrosion with tetrazolium-based cytotoxicity assays☆

(2009) Janine Fischer et al.   Acta Biomaterialia

Autophagy, senescence and tumor dormancy in cancer therapy

(2009) David A. Gewirtz   Autophagy

Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy

(2008) Pierre-Emmanuel Puig et al.   CELL BIOLOGY INTERNATIONAL

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Pharmacological Modulation of p53 Function in Cancer Therapy

(2008) Razmik Mirzayans et al.   Current Signal Transduction Therapy

Stress-induced Premature Senescence (SIPS)

(2008) Masatoshi SUZUKI et al.   JOURNAL OF RADIATION RESEARCH