Oxidative Stress: Promoter of Allergic Sensitization to Protease Allergens?

Recent developments in the role of reactive oxygen species in allergic asthma

(2017) Jingjing Qu et al.   Journal of Thoracic Disease

House dust mite–induced asthma causes oxidative damage and DNA double-strand breaks in the lungs

(2016) Tze Khee Chan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway epithelial dual oxidase 1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses

(2016) Milena Hristova et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 promotes the induction of immunoglobulin production after inhalation of house dust mite extract in mice

(2015) D. Canbaz et al.   ALLERGY

Allergic sensitization is associated with inadequate antioxidant responses in mice and men

(2015) L. Utsch et al.   ALLERGY

Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function

(2015) Thomas E. Sussan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mitochondrial-Targeted Antioxidant Therapy Decreases Transforming Growth Factor-β–Mediated Collagen Production in a Murine Asthma Model

(2015) Omar A. Jaffer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma

(2015) Ahmed Nadeem et al.   IMMUNOLOGY

Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

(2015) Christina A. Christianson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway Epithelium Interactions with Aeroallergens: Role of Secreted Cytokines and Chemokines in Innate Immunity

(2015) Vivek D. Gandhi et al.   Frontiers in Immunology

Pathophysiology of circulating xanthine oxidoreductase: New emerging roles for a multi-tasking enzyme

(2014) Maria Giulia Battelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Acute glutathione depletion leads to enhancement of airway reactivity and inflammation via p38MAPK-iNOS pathway in allergic mice

(2014) A. Nadeem et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Alternaria-derived serine protease activity drives IL-33–mediated asthma exacerbations

(2014) Robert J. Snelgrove et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter

(2014) M. A. Williams et al.   JOURNAL OF IMMUNOLOGY

Evaluation on Potential Contributions of Protease Activated Receptors Related Mediators in Allergic Inflammation

(2014) Huiyun Zhang et al.   MEDIATORS OF INFLAMMATION

Protease-Activated Receptor-2 Activation Contributes to House Dust Mite-Induced IgE Responses in Mice

(2014) Sijranke Post et al.   PLoS One

Proteinase-activated receptor-2 activation participates in allergic sensitization to house dust mite allergens in a murine model

(2013) C. E. Davidson et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Mitochondria-derived Hydrogen Peroxide Selectively Enhances T Cell Receptor-initiated Signal Transduction

(2013) Tejpal Gill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Factor-erythroid 2 (NF-E2) p45-related Factor-2 (Nrf2) Modulates Dendritic Cell Immune Function through Regulation of p38 MAPK-cAMP-responsive Element Binding Protein/Activating Transcription Factor 1 Signaling

(2013) Laith M. A. Al-Huseini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 Deficiency in Dendritic Cells Enhances the Adjuvant Effect of Ambient Ultrafine Particles on Allergic Sensitization

(2013) Ning Li et al.   Journal of Innate Immunity

Regulation of NF-B-Induced Inflammatory Signaling by Lipid Peroxidation-Derived Aldehydes

(2013) Umesh C. S. Yadav et al.   Oxidative Medicine and Cellular Longevity

Expression and secretion of Aspergillus fumigatus proteases are regulated in response to different protein substrates

(2012) Edward Farnell et al.   Fungal Biology

Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides

(2011) R. Vinhas et al.   ALLERGY

Epithelial, dendritic, and CD4+ T cell regulation of and by reactive oxygen and nitrogen species in allergic sensitization

(2011) Karina Ckless et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Serine protease Per a 10 from Periplaneta americana bias dendritic cells towards type 2 by upregulating CD86 and low IL-12 secretions

(2011) C. Goel et al.   CLINICAL AND EXPERIMENTAL ALLERGY

An Unexpected Role for Uric Acid as an Inducer of T Helper 2 Cell Immunity to Inhaled Antigens and Inflammatory Mediator of Allergic Asthma

(2011) Mirjam Kool et al.   IMMUNITY

Protease-Mediated House Dust Mite Allergen-Induced Reactive Oxygen Species Production by Neutrophils

(2011) Makiko Fukunaga et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Reactive Carbonyls Are a Major Th2-Inducing Damage-Associated Molecular Pattern Generated by Oxidative Stress

(2011) A. E. Moghaddam et al.   JOURNAL OF IMMUNOLOGY

The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation

(2011) S Post et al.   THORAX

Therapeutic Targeting of Mitochondrial Superoxide in Hypertension

(2010) Anna E. Dikalova et al.   CIRCULATION RESEARCH

Pollen-Induced Oxidative Stress Influences Both Innate and Adaptive Immune Responses via Altering Dendritic Cell Functions

(2010) Aniko Csillag et al.   JOURNAL OF IMMUNOLOGY

Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

(2010) Nita Radhakrishnan et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

The T helper type 2 response to cysteine proteases requires dendritic cell–basophil cooperation via ROS-mediated signaling

(2010) Hua Tang et al.   NATURE IMMUNOLOGY

Toll/IL-1 Signaling Is Critical for House Dust Mite–specific Th1 and Th2 Responses

(2009) Simon Phipps et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dual Inhibition of Cathepsin G and Chymase Is Effective in Animal Models of Pulmonary Inflammation

(2009) Bruce E. Maryanoff et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Suppression by CD4+CD25+ Regulatory T Cells Is Dependent on Expression of Heme Oxygenase-1 in Antigen-Presenting Cells

(2008) James F. George et al.   AMERICAN JOURNAL OF PATHOLOGY

Autoimmunity and oxidatively modified autoantigens

(2008) Biji T. Kurien et al.   AUTOIMMUNITY REVIEWS

Characterization of Proteases, Proteins, and Eicosanoid-Like Substances in Soluble Extracts from Allergenic Pollen Grains

(2008) Hendra Gunawan et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Lung dendritic cells are stimulated by ultrafine particles and play a key role in particle adjuvant activity

(2008) Colin de Haar et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mite and Cockroach Allergens Activate Protease-Activated Receptor 2 and Delay Epidermal Permeability Barrier Recovery

(2008) Se Kyoo Jeong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY