Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of Cholangiocarcinoma

Epigenetics: The third pillar of nitric oxide signaling

(2017) Samantha Socco et al.   PHARMACOLOGICAL RESEARCH

Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome

(2016) Noël J.-M. Raynal et al.   MOLECULAR CANCER THERAPEUTICS

Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response

(2016) Yoshimasa Saito et al.   Scientific Reports

Reducing DNA methylation suppresses colon carcinogenesis by inducing tumor cell differentiation

(2015) Yuichiro Hatano et al.   CARCINOGENESIS

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

(2015) David Roulois et al.   CELL

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

Activation of the innate immune response by endogenous retroviruses

(2015) Tara P. Hurst et al.   JOURNAL OF GENERAL VIROLOGY

Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma

(2015) Jinghan Wang et al.   Oncotarget

DNA Methyltransferase Inhibitor Zebularine Induces Human Cholangiocarcinoma Cell Death through Alteration of DNA Methylation Status

(2015) Kazuaki Nakamura et al.   PLoS One

Alterations of immune response of non-small cell lung cancer with Azacytidine

(2015) John Wrangle et al.   Oncotarget

Outcomes of HER2-positive early breast cancer patients in the pre-trastuzumab and trastuzumab eras: a real-world multicenter observational analysis. The RETROHER study

(2014) Patrizia Vici et al.   BREAST CANCER RESEARCH AND TREATMENT

Silencing ofmicroRNA-122is an early event during hepatocarcinogenesis from non-alcoholic steatohepatitis

(2014) Yoko Takaki et al.   CANCER SCIENCE

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

The novel colorectal cancer biomarkersCDO1, ZSCAN18andZNF331are frequently methylated across gastrointestinal cancers

(2014) Hege Marie Vedeld et al.   INTERNATIONAL JOURNAL OF CANCER

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

Inhibitors of enhancer of zeste homolog 2 (EZH2) activate tumor-suppressor microRNAs in human cancer cells

(2014) S Hibino et al.   Oncogenesis

Aberrant DNA Methylation at Genes Associated with a Stem Cell-like Phenotype in Cholangiocarcinoma Tumors

(2013) R. Sriraksa et al.   Cancer Prevention Research

Epigenetic Alterations and MicroRNA Misexpression in Cancer and Autoimmune Diseases: a Critical Review

(2013) Yoshimasa Saito et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Alterations of epigenetics and microRNA in hepatocellular carcinoma

(2013) Yoshimasa Saito et al.   HEPATOLOGY RESEARCH

Targeted Drug Regulation on Methylation of p53—BAX Mitochondrial Apoptosis Pathway Affects the Growth of Cholangiocarcinoma Cells

(2013) X-F Liu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

MiR-376c Down-Regulation Accelerates EGF-Dependent Migration by Targeting GRB2 in the HuCCT1 Human Intrahepatic Cholangiocarcinoma Cell Line

(2013) Jun Iwaki et al.   PLoS One

si-DNMT1 restore tumor suppressor genes expression through the reversal of DNA hypermethylation in cholangiocarcinoma

(2013) Jifeng Xiang et al.   Clinics and Research in Hepatology and Gastroenterology

Bile-Based Detection of Extrahepatic Cholangiocarcinoma with Quantitative DNA Methylation Markers and Its High Sensitivity

(2012) So-Hyun Shin et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Correlation between promoter methylation of p14ARF, TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinoma

(2012) Liu Xiaofang et al.   World Journal of Surgical Oncology

Clinical diagnosis and staging of cholangiocarcinoma

(2011) Boris Blechacz et al.   Nature Reviews Gastroenterology & Hepatology

hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing

(2010) Chung-Fan Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes

(2009) Chiara Braconi et al.   HEPATOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Aberrant Promoter CpG Islands Methylation of Tumor Suppressor Genes in Cholangiocarcinoma

(2008) Kyung-Ok Uhm et al.   ONCOLOGY RESEARCH

Cancer Epigenetics: Modifications, Screening, and Therapy

(2007) Gal-Yam Einav Nili et al.   Annual Review of Medicine