Inhaled Pollutants: The Molecular Scene behind Respiratory and Systemic Diseases Associated with Ultrafine Particulate Matter

The complexity of the translation ability of circRNAs

(2016) Javier T. Granados-Riveron et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero

(2016) Daniel M. Rotroff et al.   BMC GENOMICS

Associations of oxidative stress and inflammatory biomarkers with chemically-characterized air pollutant exposures in an elderly cohort

(2016) Xian Zhang et al.   ENVIRONMENTAL RESEARCH

Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood

(2016) Christine Ladd-Acosta et al.   ENVIRONMENTAL RESEARCH

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

Health Outcomes of Exposure to Biological and Chemical Components of Inhalable and Respirable Particulate Matter

(2016) Oyewale Morakinyo et al.   International Journal of Environmental Research and Public Health

Autophagy is essential for ultrafine particle-induced inflammation and mucus hyperproduction in airway epithelium

(2015) Zhi-Hua Chen et al.   Autophagy

Angiopoietin-1 inhibits toll-like receptor 4 signalling in cultured endothelial cells: role of miR-146b-5p

(2015) Raquel Echavarria et al.   CARDIOVASCULAR RESEARCH

In vitro cytotoxicity of gold nanorods in A549 cells

(2015) Ying Tang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1

(2015) Miles Sarill et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alterations in DNA methylation and airway hyperreactivity in response toin uteroexposure to environmental tobacco smoke

(2015) Joong Won Lee et al.   INHALATION TOXICOLOGY

Incomplete lung recovery following sub-acute inhalation of combustion-derived ultrafine particles in mice

(2015) A. Noël et al.   Particle and Fibre Toxicology

Comparison of cellular toxicity caused by ambient ultrafine particles and engineered metal oxide nanoparticles

(2015) Senlin Lu et al.   Particle and Fibre Toxicology

A conserved charged single α-helix with a putative steric role in paraspeckle formation

(2015) László Dobson et al.   RNA

Oxidative and pro-inflammatory effects of cobalt and titanium oxide nanoparticles on aortic and venous endothelial cells

(2015) Rossella Alinovi et al.   TOXICOLOGY IN VITRO

Effects of silver and gold nanoparticles of different sizes in human pulmonary fibroblasts

(2015) Alicia Ávalos et al.   TOXICOLOGY MECHANISMS AND METHODS

Effects of silver and gold nanoparticles of different sizes in human pulmonary fibroblasts

(2015) Alicia Ávalos et al.   TOXICOLOGY MECHANISMS AND METHODS

Ceria Nanoparticles Stabilized by Organic Surface Coatings Activate the Lysosome-Autophagy System and Enhance Autophagic Clearance

(2014) Wensi Song et al.   ACS Nano

Effects of Titanium Dioxide Nanoparticles Isolated from Confectionery Products on the Metabolic Stress Pathway in Human Lung Fibroblast Cells

(2014) Vaiyapuri Subbarayan Periasamy et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Vehicle Engines Produce Exhaust Nanoparticles Even When Not Fueled

(2014) Topi Rönkkö et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Silicon dioxide nanoparticles increase macrophage atherogenicity: Stimulation of cellular cytotoxicity, oxidative stress, and triglycerides accumulation

(2014) Lauren Petrick et al.   ENVIRONMENTAL TOXICOLOGY

Silica nanoparticles induce autophagy and endothelial dysfunction via the PI3K/Akt/mTOR signaling pathway

(2014) Duan et al.   International Journal of Nanomedicine

Physicochemical characteristics of nanomaterials that affect pulmonary inflammation

(2014) Hedwig M Braakhuis et al.   Particle and Fibre Toxicology

Necroptosis, in vivo detection in experimental disease models

(2014) Sandrine Jouan-Lanhouet et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Aryl Hydrocarbon Receptor (AhR) Attenuation of Subchronic Cigarette Smoke-induced Pulmonary Neutrophilia Is Associated with Retention of Nuclear RelB and Suppression of Intercellular Adhesion Molecule-1 (ICAM-1)

(2014) Angela Rico de Souza et al.   TOXICOLOGICAL SCIENCES

Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation

(2014) Emelia Hecht et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The NF-κB family member RelB regulates microRNA miR-146a to suppress cigarette smoke-induced COX-2 protein expression in lung fibroblasts

(2014) Michela Zago et al.   TOXICOLOGY LETTERS

Zinc oxide nanoparticles induce apoptosis by enhancement of autophagy via PI3K/Akt/mTOR inhibition

(2014) Ruchi Roy et al.   TOXICOLOGY LETTERS

Effect of cigarette smoke condensate on gene promoter methylation in human lung cells

(2014) Lascelles Lyn-Cook et al.   Tobacco Induced Diseases

Combustion derived ultrafine particles induce cytochrome P-450 expression in specific lung compartments in the developing neonatal and adult rat

(2013) Jackie K. W. Chan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Age-Specific Effects on Rat Lung Glutathione and Antioxidant Enzymes after Inhaling Ultrafine Soot

(2013) Jackie K. W. Chan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of a Novel Long Noncoding RNA, SCAL1, Induced by Cigarette Smoke and Elevated in Lung Cancer Cell Lines

(2013) Philip Thai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Postnatal stability, tissue, and time specific effects ofAHRRmethylation change in response to maternal smoking in pregnancy

(2013) Boris Novakovic et al.   Epigenetics

TFEB regulates lysosomal proteostasis

(2013) Wensi Song et al.   HUMAN MOLECULAR GENETICS

Induction of miR-21-PDCD4 Signaling by Tungsten Carbide-Cobalt Nanoparticles in JB6 Cells Involves ROS-Mediated MAPK Pathways

(2013) Lichao Hou et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Nrf2 Deficiency in Dendritic Cells Enhances the Adjuvant Effect of Ambient Ultrafine Particles on Allergic Sensitization

(2013) Ning Li et al.   Journal of Innate Immunity

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

(2013) Takashi Nagano et al.   NANOTECHNOLOGY

Toxicity and bio-accumulation of inhaled cerium oxide nanoparticles in CD1 mice

(2013) Srinivas Aalapati et al.   Nanotoxicology

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts

(2013) Sarah Geisler et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Placental DNA hypomethylation in association with particulate air pollution in early life

(2013) Bram G Janssen et al.   Particle and Fibre Toxicology

Maternal exposure to combustion generated PM inhibits pulmonary Th1 maturation and concomitantly enhances postnatal asthma development in offspring

(2013) Pingli Wang et al.   Particle and Fibre Toxicology

Resolution of inflammation: Mechanisms and opportunity for drug development

(2013) Ana L. Alessandri et al.   PHARMACOLOGY & THERAPEUTICS

Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

(2013) Sonja Zeilinger et al.   PLoS One

Apoptotic and proinflammatory effect of combustion-generated organic nanoparticles in endothelial cells

(2013) Paola Pedata et al.   TOXICOLOGY LETTERS

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of theIn VivoandIn VitroStudies

(2013) Abderrahim Nemmar et al.   Biomed Research International

Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers

(2012) Martha M. Monick et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Short- and long-term changes in blood miRNA levels after nanogold injection in rats—potential biomarkers of nanoparticle exposure

(2012) Wee-Siong Chew et al.   BIOMARKERS

TiO2 Nanoparticles Induce Dysfunction and Activation of Human Endothelial Cells

(2012) Angélica Montiel-Dávalos et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung

(2012) Julie A. Bourdon et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy

(2012) Bonnie R. Joubert et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Demethylation of the aryl hydrocarbon receptor repressor as a biomarker for nascent smokers

(2012) Robert A. Philibert et al.   Epigenetics

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

(2012) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2Sensing and Signaling

(2012) Kathryn M. Oliver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative damage of lung and its protective mechanism in mice caused by long-term exposure to titanium dioxide nanoparticles

(2012) Qingqing Sun et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells

(2012) Anne Brüstle et al.   JOURNAL OF CLINICAL INVESTIGATION

Long Noncoding RNAs with snoRNA Ends

(2012) Qing-Fei Yin et al.   MOLECULAR CELL

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

(2012) Hiromi Nabeshi et al.   NANOTECHNOLOGY

Epigenetic effects of nano-sized materials

(2012) Andrea Stoccoro et al.   TOXICOLOGY

Methylation of PARP-1 promoter involved in the regulation of nano-SiO2-induced decrease of PARP-1 mRNA expression

(2012) Chunmei Gong et al.   TOXICOLOGY LETTERS

Lung-Targeted Overexpression of the NF-κB Member RelB Inhibits Cigarette Smoke–Induced Inflammation

(2011) David H. McMillan et al.   AMERICAN JOURNAL OF PATHOLOGY

Nanoparticles in cigarette smoke; real-time undiluted measurements by a scanning mobility particle sizer

(2011) Wouter D. van Dijk et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study

(2011) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Role of size and composition of traffic and agricultural aerosols in the molecular responses triggered in airway epithelial cells

(2011) Val Stéphanie et al.   INHALATION TOXICOLOGY

TNF -induced noncanonical NF- B activation is attenuated by RIP1 through stabilization of TRAF2

(2011) J.-Y. Kim et al.   JOURNAL OF CELL SCIENCE

Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in Macrophages

(2011) C.-Y. Tsai et al.   JOURNAL OF IMMUNOLOGY

Specific peripheral miRNA profiles for distinguishing lung cancer from COPD

(2011) Petra Leidinger et al.   LUNG CANCER

Genotoxic effects of silver nanoparticles stimulated by oxidative stress in human normal bronchial epithelial (BEAS-2B) cells

(2011) Ha Ryong Kim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Contribution of nano-copper particles toin vivoliver dysfunction and cellular damage: Role of IκBα/NF-κB, MAPKs and mitochondrial signal

(2011) Prasenjit Manna et al.   Nanotoxicology

Mechanisms of cellular adaptation to quantum dots – the role of glutathione and transcription factor EB

(2011) Kevin D. Neibert et al.   Nanotoxicology

Inflammatory responses of RAW 264.7 macrophages upon exposure to nanoparticles: Role of ROS-NFκB signaling pathway

(2011) Reddy P. Nishanth et al.   Nanotoxicology

In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential - the RAPTES project

(2011) Maaike Steenhof et al.   Particle and Fibre Toxicology

TFEB Links Autophagy to Lysosomal Biogenesis

(2011) C. Settembre et al.   SCIENCE

Combination effects of cigarette smoke extract and ambient ultrafine particles on endothelial cells

(2011) Yiqun Mo et al.   TOXICOLOGY IN VITRO

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

(2011) H-L Liu et al.   Cell Death & Disease

MicroRNA Expression in Induced Sputum of Smokers and Patients with Chronic Obstructive Pulmonary Disease

(2010) Geert R. Van Pottelberge et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SiO2 nanoparticles induce global genomic hypomethylation in HaCaT cells

(2010) Chunmei Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy and oxidative stress associated with gold nanoparticles

(2010) Jasmine J. Li et al.   BIOMATERIALS

Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-κB pathways

(2010) Xin Liu et al.   BIOMATERIALS

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

(2010) Nobuyoshi Kosaka et al.   CANCER SCIENCE

Phosphorylation of p65 Is Required for Zinc Oxide Nanoparticle–Induced Interleukin 8 Expression in Human Bronchial Epithelial Cells

(2010) Weidong Wu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Environmental epigenetics

(2010) V Bollati et al.   HEREDITY

Oxidative Injury in The Lungs of Neonatal Rats Following Short-Term Exposure to Ultrafine Iron and Soot Particles

(2010) Cai-Yun Zhong et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

MicroRNA control of signal transduction

(2010) Masafumi Inui et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evidence for natural antisense transcript-mediated inhibition of microRNA function

(2010) Mohammad Ali Faghihi et al.   GENOME BIOLOGY

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer

(2009) Elena Gallardo et al.   CARCINOGENESIS

Disruption of MicroRNA Expression in Human Airway Cells by Diesel Exhaust Particles Is Linked to Tumorigenesis-Associated Pathways

(2009) Melanie J. Jardim et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage

(2009) Yu Pan et al.   Small

Oxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2B

(2009) Hyun-Jeong Eom et al.   TOXICOLOGY IN VITRO

Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2B

(2009) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

PVP-coated silver nanoparticles and silver ions induce reactive oxygen species, apoptosis and necrosis in THP-1 monocytes

(2009) Rasmus Foldbjerg et al.   TOXICOLOGY LETTERS

Ambient Particulate Pollutants in the Ultrafine Range Promote Early Atherosclerosis and Systemic Oxidative Stress

(2008) Jesus A. Araujo et al.   CIRCULATION RESEARCH

Effects of Particulate Matter on Genomic DNA Methylation Content and iNOS Promoter Methylation

(2008) Letizia Tarantini et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

(2008) Alberto Izzotti et al.   FASEB JOURNAL

The Aryl Hydrocarbon Receptor Attenuates Tobacco Smoke-induced Cyclooxygenase-2 and Prostaglandin Production in Lung Fibroblasts through Regulation of the NF-κB Family Member RelB

(2008) Carolyn J. Baglole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers

(2008) Enrique Zudaire et al.   JOURNAL OF CLINICAL INVESTIGATION

Airborne Particulate Matter and Human Health: Toxicological Assessment and Importance of Size and Composition of Particles for Oxidative Damage and Carcinogenic Mechanisms

(2008) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

The next innovation cycle in toxicogenomics: Environmental epigenetics

(2008) S REAMONBUETTNER et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice

(2007) Tomonori Hosoya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS