Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
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Title
Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice
Authors
Keywords
Phytocannabinoids, cannabigerol, Huntington’s disease, inflammation, neuroprotection
Journal
Neurotherapeutics
Volume 12, Issue 1, Pages 185-199
Publisher
Springer Nature
Online
2014-09-25
DOI
10.1007/s13311-014-0304-z
References
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- (2013) Jing Jin et al. JOURNAL OF NEUROCHEMISTRY
- MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington’s Disease-Related Mechanisms
- (2013) Ana Jovicic et al. PLoS One
- Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB1 and CB2 Receptors
- (2012) Sara Valdeolivas et al. ACS Chemical Neuroscience
- Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
- (2012) Javier Fernández-Ruiz et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis
- (2012) Aitor G. Granja et al. Journal of Neuroimmune Pharmacology
- Role of Cannabinoids in Multiple Sclerosis
- (2011) John P. Zajicek et al. CNS DRUGS
- THC and CBD oromucosal spray (Sativex®) in the management of spasticity associated with multiple sclerosis
- (2011) Jaume Sastre-Garriga et al. Expert Review of Neurotherapeutics
- Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease
- (2011) Ashu Johri et al. HUMAN MOLECULAR GENETICS
- Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease
- (2011) Onintza Sagredo et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Phytocannabinoids as novel therapeutic agents in CNS disorders
- (2011) Andrew J. Hill et al. PHARMACOLOGY & THERAPEUTICS
- SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
- (2011) Michal Mielcarek et al. PLoS One
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour
- (2011) Serena Deiana et al. PSYCHOPHARMACOLOGY
- Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease
- (2010) Cristina Blázquez et al. BRAIN
- The endocannabinoid system as a target for the treatment of neuronal damage
- (2010) Javier Fernández-Ruiz et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Huntington's disease: progress toward effective disease-modifying treatments and a cure
- (2010) C. D. Johnson et al. HUMAN MOLECULAR GENETICS
- Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression
- (2010) M. A. Pouladi et al. HUMAN MOLECULAR GENETICS
- Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
- (2010) Chiara Zuccato et al. PHYSIOLOGICAL REVIEWS
- Increased numbers of motor activity peaks during light cycle are associated with reductions in adrenergic α2-receptor levels in a transgenic Huntington's disease rat model
- (2009) Felix J. Bode et al. BEHAVIOURAL BRAIN RESEARCH
- Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity
- (2009) Javier Palazuelos et al. BRAIN
- Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist
- (2009) MG Cascio et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease
- (2009) Onintza Sagredo et al. GLIA
- Diminished hippocalcin expression in Huntington’s disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons
- (2009) Nikita Rudinskiy et al. JOURNAL OF NEUROCHEMISTRY
- A pilot study using nabilone for symptomatic treatment in Huntington's disease
- (2009) Adrienne Curtis et al. MOVEMENT DISORDERS
- Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters
- (2009) Ana María Estrada-Sánchez et al. NEUROBIOLOGY OF DISEASE
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
- (2009) Angelo A. Izzo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The Endocannabinoid System in Huntingtons Disease
- (2008) M. Pazos et al. CURRENT PHARMACEUTICAL DESIGN
- Rosiglitazone Treatment Prevents Mitochondrial Dysfunction in Mutant Huntingtin-expressing Cells
- (2008) Rodrigo A. Quintanilla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice
- (2008) M. Gray et al. JOURNAL OF NEUROSCIENCE
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- (2008) Barbara L. Apostol et al. MOLECULAR AND CELLULAR NEUROSCIENCE
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