Neuroprotective Mechanisms of the ACE2–Angiotensin-(1-7)–Mas Axis in Stroke
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuroprotective Mechanisms of the ACE2–Angiotensin-(1-7)–Mas Axis in Stroke
Authors
Keywords
Angiotensin converting enzyme 2, Angiotensin-(1-7), Mas, Angiotensin type 1 receptor, Angiotensin type 2 receptor, Renin-angiotensin system, Stroke, Neuroprotection, Neuron, Microglia, Ischemia, Intracerebral hemorrhage, Inflammation
Journal
CURRENT HYPERTENSION REPORTS
Volume 17, Issue 2, Pages -
Publisher
Springer Nature
Online
2015-01-26
DOI
10.1007/s11906-014-0512-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Direct evidence of intracrine angiotensin II signaling in neurons
- (2014) Elena Deliu et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Promising neuroprotective effects of the angiotensin-(1-7)-angiotensin-converting enzyme 2-Mas axis in stroke
- (2014) Ricardo A. Peña Silva et al. EXPERIMENTAL PHYSIOLOGY
- Diminazene aceturate (Berenil), a new use for an old compound?
- (2014) Shiby Kuriakose et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke
- (2014) Jason P. Joseph et al. NEUROPHARMACOLOGY
- Neuronal over-expression of ACE2 protects brain from ischemia-induced damage
- (2014) Ji Chen et al. NEUROPHARMACOLOGY
- Activation of the ACE2/Ang-(1–7)/Mas pathway reduces oxygen–glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction
- (2014) J. Zheng et al. NEUROSCIENCE
- Direct Angiotensin AT2 Receptor Stimulation Using a Novel AT2 Receptor Agonist, Compound 21, Evokes Neuroprotection in Conscious Hypertensive Rats
- (2014) Claudia A. McCarthy et al. PLoS One
- ACE2/Ang-(1–7) signaling and vascular remodeling
- (2014) ZhenZhou Zhang et al. Science China-Life Sciences
- Cerebroprotective action of angiotensin peptides in stroke
- (2013) Robert W. Regenhardt et al. CLINICAL SCIENCE
- ACE2-Ang-(1-7)-Mas Axis in Brain: A Potential Target for Prevention and Treatment of Ischemic Stroke
- (2013) Teng Jiang et al. Current Neuropharmacology
- Angiotensin-(1–7) prevents radiation-induced inflammation in rat primary astrocytes through regulation of MAP kinase signaling
- (2013) Elizabeth D. Moore et al. FREE RADICAL BIOLOGY AND MEDICINE
- Angiotensin-Converting Enzyme 2 Activation Improves Endothelial Function
- (2013) Rodrigo A. Fraga-Silva et al. HYPERTENSION
- Possible Role of Angiotensin-Converting Enzyme 2 and Activation of Angiotensin II Type 2 Receptor by Angiotensin-(1–7) in Improvement of Vascular Remodeling by Angiotensin II Type 1 Receptor Blockade
- (2013) Kousei Ohshima et al. HYPERTENSION
- Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS
- (2013) Vaibhav B. Patel et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Complete blockade of the vasorelaxant effects of angiotensin-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas
- (2013) Concepción Peiró et al. JOURNAL OF PHYSIOLOGY-LONDON
- ACE2 Activation Confers Endothelial Protection and Attenuates Neointimal Lesions in Prevention of Severe Pulmonary Arterial Hypertension in Rats
- (2013) Gang Li et al. LUNG
- Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke
- (2013) Robert W. Regenhardt et al. NEUROPHARMACOLOGY
- Oral Angiotensin-(1–7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-κB in rats fed with high-fat diet
- (2013) Sérgio Henrique Sousa Santos et al. PEPTIDES
- Angiotensin-(1-7) inhibits vascular calcification in rats
- (2013) Yu-Bin Sui et al. PEPTIDES
- Preclinical Stroke Research: Gains and Gaps
- (2013) D. A. Greenberg STROKE
- Guidelines for the Early Management of Patients With Acute Ischemic Stroke
- (2013) Edward C. Jauch et al. STROKE
- Angiotensin converting enzyme 2 and atherosclerosis
- (2012) Yutang Wang et al. ATHEROSCLEROSIS
- Angiotensin-(1–7) regulates Angiotensin II-induced VCAM-1 expression on vascular endothelial cells
- (2012) Feng Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways
- (2012) Ahmed Z El-Hashim et al. BRITISH JOURNAL OF PHARMACOLOGY
- Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia
- (2012) Teng Jiang et al. BRITISH JOURNAL OF PHARMACOLOGY
- Angiotensin-(1–7): beyond the cardio-renal actions
- (2012) Danielle G. Passos-Silva et al. CLINICAL SCIENCE
- Angiotensin II Type 2 Receptor Stimulation Initiated After Stroke Causes Neuroprotection in Conscious Rats
- (2012) Claudia A. McCarthy et al. HYPERTENSION
- Angiotensin-Converting Enzyme 2 Priming Enhances the Function of Endothelial Progenitor Cells and Their Therapeutic Efficacy
- (2012) Ji Chen et al. HYPERTENSION
- Hemodynamic effects of vasorelaxant compounds in mice lacking one, two or all three angiotensin II receptors
- (2012) Florian Gembardt et al. HYPERTENSION RESEARCH
- Angiotensin-(1-7) modulates renin–angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats
- (2012) Teng Jiang et al. PHARMACOLOGICAL RESEARCH
- Reducing the Global Burden of Ischemic Heart Disease and Stroke
- (2011) Sidney C. Smith CIRCULATION
- Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist
- (2011) Roelie M Wösten-van Asperen et al. JOURNAL OF PATHOLOGY
- Differential Mechanisms of Ang (1-7)-Mediated Vasodepressor Effect in Adult and Aged Candesartan-Treated Rats
- (2011) S. Bosnyak et al. International Journal of Hypertension
- Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries
- (2010) Matthew J. Durand et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Angiotensin-(1–7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats
- (2010) María A. Costa et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- ACE2/ANG-(1–7)/Mas pathway in the brain: the axis of good
- (2010) Ping Xu et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Vasoprotective and Atheroprotective Effects of Angiotensin (1-7) in Apolipoprotein E–Deficient Mice
- (2010) Sonja Tesanovic et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Angiotensin type 1 receptor antagonist inhibits lipopolysaccharide-induced stimulation of rat microglial cells by suppressing nuclear factor κB and activator protein-1 activation
- (2010) Michio Miyoshi et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Angiotensin II sustains brain inflammation in mice via TGF-β
- (2010) Tobias V. Lanz et al. JOURNAL OF CLINICAL INVESTIGATION
- Anti-Inflammatory Effects of the Activation of the Angiotensin-(1-7) Receptor, Mas, in Experimental Models of Arthritis
- (2010) K. D. da Silveira et al. JOURNAL OF IMMUNOLOGY
- Evidence for Angiotensin-converting Enzyme 2 as a Therapeutic Target for the Prevention of Pulmonary Hypertension
- (2009) Anderson J. Ferreira et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Phase I and Pharmacokinetic Study of Angiotensin-(1-7), an Endogenous Antiangiogenic Hormone
- (2009) W. J. Petty et al. CLINICAL CANCER RESEARCH
- Candesartan pretreatment is cerebroprotective in a rat model of endothelin-1-induced middle cerebral artery occlusion
- (2009) Adam P. Mecca et al. EXPERIMENTAL PHYSIOLOGY
- Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage
- (2009) Paolo Gelosa et al. JOURNAL OF HYPERTENSION
- Angiotensin II Up-Regulates Angiotensin I-Converting Enzyme (ACE), but Down-Regulates ACE2 via the AT1-ERK/p38 MAP Kinase Pathway
- (2008) Vijay Koka et al. AMERICAN JOURNAL OF PATHOLOGY
- MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides
- (2008) Patricia E. Gallagher et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Effects of intracerebroventricular infusion of angiotensin-(1–7) on bradykinin formation and the kinin receptor expression after focal cerebral ischemia–reperfusion in rats
- (2008) Jie Lu et al. BRAIN RESEARCH
- Transgenic Angiotensin-Converting Enzyme 2 Overexpression in Vessels of SHRSP Rats Reduces Blood Pressure and Improves Endothelial Function
- (2008) Brit Rentzsch et al. HYPERTENSION
- Central administration of angiotensin-(1–7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats
- (2008) Yingdong Zhang et al. NEUROPEPTIDES
- Neuroprotection for ischemic stroke: Past, present and future
- (2008) Myron D. Ginsberg NEUROPHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation