Inhibition of PKR ameliorates lipopolysaccharide-induced acute lung injury by suppressing NF-κB pathway in mice

Lipopolysaccharide Induces Autophagic Cell Death through the PERK-Dependent Branch of the Unfolded Protein Response in Human Alveolar Epithelial A549 Cells

(2015) Shaoying Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response

(2015) Alexandre Dalet et al.   FEBS LETTERS

Ginsenoside Rg1 improves lipopolysaccharide-induced acute lung injury by inhibiting inflammatory responses and modulating infiltration of M2 macrophages

(2015) Suhong Bao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The protective effect of CDDO-Me on lipopolysaccharide-induced acute lung injury in mice

(2015) Tong Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Altered Activation of Protein Kinase PKR and Enhanced Apoptosis in Dystonia Cells Carrying a Mutation in PKR Activator Protein PACT

(2015) Lauren S Vaughn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of acteoside on lipopolysaccharide-induced inflammation in acute lung injury via regulation of NF-κB pathway in vivo and in vitro

(2015) Wang Jing et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis

(2015) Wei-Chieh Lin et al.   Scientific Reports

Human Resistin Promotes Neutrophil Proinflammatory Activation and Neutrophil Extracellular Trap Formation and Increases Severity of Acute Lung Injury

(2014) S. Jiang et al.   JOURNAL OF IMMUNOLOGY

Antithrombin Attenuates Vascular Leakage via Inhibiting Neutrophil Activation in Acute Lung Injury

(2013) Sebastian Rehberg et al.   CRITICAL CARE MEDICINE

The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component

(2013) C. Tronel et al.   NEUROCHEMISTRY INTERNATIONAL

Human Mesenchymal Stem Cell Microvesicles for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice

(2013) Ying-gang Zhu et al.   STEM CELLS

Pharmacological Inhibition of PKR in APPswePS1dE9 Mice Transiently Prevents Inflammation at 12 Months of Age but Increases Aβ42 Levels in the Late Stages of the Alzheimer’s Disease

(2012) Julien Couturier et al.   Current Alzheimer Research

The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material

(2012) Niall D. Ferguson et al.   INTENSIVE CARE MEDICINE

NF-κB Directly Regulates Fas Transcription to Modulate Fas-mediated Apoptosis and Tumor Suppression

(2012) Feiyan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel role of PKR in inflammasome activation and HMGB1 release

(2012) Ben Lu et al.   NATURE

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures

(2011) J Couturier et al.   Journal of Neuroinflammation

Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro

(2010) Junpei Teramachi et al.   EXPERIMENTAL CELL RESEARCH

The role of apoptosis in the pathophysiology of Acute Respiratory Distress Syndrome (ARDS): An up-to-date cell-specific review

(2010) Vasiliki Galani et al.   PATHOLOGY RESEARCH AND PRACTICE

Interaction of Double-stranded RNA-dependent Protein Kinase (PKR) with the Death Receptor Signaling Pathway in Amyloid β (Aβ)-treated Cells and in APPSLPS1 Knock-in Mice

(2009) Julien Couturier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease

(2009) Milena Morel et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Double-Stranded RNA-Activated Protein Kinase Regulates Early Innate Immune Responses During Respiratory Syncytial Virus Infection

(2009) Radiah A. Corn Minor et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

PKR Regulates TLR2/TLR4-Dependent Signaling in Murine Alveolar Macrophages

(2007) Maciej Cabanski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY